Ligand-directed targeting of lymphatic vessels uncovers mechanistic insights in melanoma metastasis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 8, 2015, Pages 2521-2526

  Christianson, Dawn R ^a,h   Dobroff, Andrey S ^b,c   Proneth, Bettina ^a,i   Zurita, Amado J ^a   Salameh, Ahmad ^a,j   Dondossola, Eleonora ^a   Makino, Jun ^d   Bologa, Cristian G ^c   Smith, Tracey L ^b,c   Yao, Virginia J ^b,c   Calderone, Tiffany L ^a   Connell, David J O' ^e   Oprea, Tudor I ^c   Kataoka, Kazunori ^f   Cahill, Dolores J ^e   Gershenwald, Jeffrey E ^a   Sidman, Richard L ^g   Arap, Wadih ^b,c   Pasqualini, Renata ^b,c  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

^c UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TOKYO   (Japan)

^e UNIVERSITY COLLEGE DUBLIN   (Ireland)

^f UNIVERSITY OF TOKYO   (Japan)

^g BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^h Arrowhead Research Corporation   (United States)

ⁱ INSTITUTE OF EPIDEMIOLOGY   (Germany)

^j UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

more..

Author keywords

Cell surface peptide; Cell cell interaction; Lymphatic targeting; Phage display

Indexed keywords

CELL SURFACE PROTEIN; HOMODIMER; LIGAND; PHOSPHATASE 2 REGULATORY SUBUNIT A ALPHA ISOFORM; PHOSPHOPROTEIN PHOSPHATASE 2A; RECEPTOR; UNCLASSIFIED DRUG; PEPTIDE; PHOSPHOPROTEIN PHOSPHATASE 2; PPP2R1A PROTEIN, HUMAN;

ALPHA CHAIN; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INTERACTION; CELL SURFACE; COMBINATORIAL LIBRARY; CONTROLLED STUDY; ENDOTHELIUM CELL; EX VIVO STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LYMPH VESSEL; LYMPH VESSEL ENDOTHELIUM; MELANOMA CELL; MELANOMA METASTASIS; MOLECULAR MIMICRY; MOUSE; NONHUMAN; PEPTIDE LIBRARY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR CELL; ANIMAL; BIOPSY; CELL COMMUNICATION; CELL MEMBRANE; CHEMISTRY; IMMUNOLOGY; LYMPH NODE METASTASIS; MELANOMA; METABOLISM; MOLECULAR GENETICS; NUDE MOUSE; PATHOLOGY; REPRODUCIBILITY; TREATMENT OUTCOME;

AMINO ACID SEQUENCE; ANIMALS; BIOPSY; CELL COMMUNICATION; CELL MEMBRANE; ENDOTHELIAL CELLS; ENDOTHELIUM, LYMPHATIC; HUMANS; LIGANDS; LYMPHATIC METASTASIS; LYMPHATIC VESSELS; MELANOMA; MICE, NUDE; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN PHOSPHATASE 2; REPRODUCIBILITY OF RESULTS; TREATMENT OUTCOME;

EID: 84923683160     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1424994112     Document Type: Article

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