Genetic and antigenic structural characterization for resistance of echovirus 11 to pleconaril in an immunocompromised patient

Journal of General Virology

Volumn 96, Issue 3, 2015, Pages 571-579

  Benschop, K S M ^a,d   Wildenbeest, J G ^a,b   Koen, G ^a   Minnaar, R P ^a   Van Hemert, F J ^a   Westerhuis, B M ^a   Pajkrt, D ^b   Van Den Broek, P J ^c   Vossen, A C T M ^c   Wolthers, K C ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b EMMA CHILDREN S HOSPITAL   (Netherlands)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN; METHIONINE; PLECONARIL; SULFATE; ANTIVIRUS AGENT; OXADIAZOLE DERIVATIVE; VIRUS ANTIGEN;

AMINO ACID SUBSTITUTION; ANTIGEN STRUCTURE; ANTIVIRAL RESISTANCE; ARTICLE; CASE REPORT; CONFORMATIONAL TRANSITION; ECHOVIRUS 11; GENE MUTATION; HEREDITY; HUMAN; HYDROPHOBICITY; IMMUNOCOMPROMISED PATIENT; IN VITRO STUDY; MENINGOENCEPHALITIS; MOLECULAR DOCKING; NONHUMAN; PRIORITY JOURNAL; SUBSTITUTION REACTION; TREATMENT FAILURE; VIRAL GENETICS; VIRUS CAPSID; VIRUS ISOLATION; VIRUS MORPHOLOGY; VIRUS STRAIN; ECHOVIRUS INFECTION; ENTEROVIRUS B; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS; VIROLOGY;

ENTEROVIRUS; HUMAN ECHOVIRUS 11; MIRIDAE;

ANTIGENS, VIRAL; ANTIVIRAL AGENTS; DRUG RESISTANCE, VIRAL; ECHOVIRUS INFECTIONS; ENTEROVIRUS B, HUMAN; GENE EXPRESSION REGULATION, VIRAL; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OXADIAZOLES;

EID: 84923673926     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.069773-0     Document Type: Article

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