Effects of histone deacetylase inhibitor trichostatin A combined with cisplatin on apoptosis of A549 cell line

Thoracic Cancer

Volumn 6, Issue 2, 2015, Pages 202-208

  Zhang, Xuan ^a   Jiang, Shu Juan ^a   Shang, Bin ^a   Jiang, Hong Juan ^a  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

Author keywords

Caspase 8; Cellular Fas associated death domain like interleulin 1 converting enzyme inhibitory protein (cFLIP); Cisplatin; Trichostatin A (TSA)

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CASPASE 8; CISPLATIN; FLICE INHIBITORY PROTEIN; TRICHOSTATIN A;

A549 CELL LINE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER THERAPY; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG POTENTIATION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; METHYL THIAZOLYL TETRAZOLIUM ASSAY; MICROSCOPY; MTT ASSAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAINING; WESTERN BLOTTING;

EID: 84923640670     PISSN: 17597706     EISSN: 17597714     Source Type: Journal    
DOI: 10.1111/1759-7714.12167     Document Type: Article

References (22)

1. Sun S, Schiller JH, Gazdar AF. Lung cancer in never smokers-a different disease. Nat Rev Cancer 2007; 7: 778-790.
2. Long N, Moore MA, Chen W etal. Cancer epidemiology and control in north-East Asia - past, present and future. Asian Pac J Cancer Prev 2010; 11 (Suppl 2): 107-148.
3. Jemal A, Siegel R, Ward E etal. Cancer statistics, 2008. CA Cancer J Clin 2008; 58: 71-96.
4. Egger G, Liang G, Aparicio A, Jones PA. Epigenetics in human disease and prospects for epigenetic therapy. Nature 2004; 429: 457-463.
5. Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat Rev Genet 2002; 3: 415-428.
6. Esteller M. CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future. Oncogene 2002; 21: 5427-5440.
7. Dowdy SC, Jiang S, Zhou XC etal. Histone deacetylase inhibitors and paclitaxel cause synergistic effects on apoptosis and microtubule stabilization in papillary serous endometrial cancer cells. Mol Cancer Ther 2006; 5: 2767-2776.
8. Kim SH, Kang HJ, Na H, Li MO. Trichostatin A enhances acetylation as well as protein stability of ERalpha through induction of p300 protein. Breast Cancer Res 2010; 12: R22.
9. Sharma P, Kumar S, Kundu GC. Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells. Mol Cancer 2010; 9: 178-179.
10. Cheng DD, Yang QC, Zhang ZC, Yang CX, Liu YW. Antitumor activity of histone deacetylase inhibitor trichostatin A in osteosarcoma cells. Asian Pac J Cancer Prev 2012; 13: 1395-1399.
11. Ranganathan P, Rangnekar VM. Exploiting the TSA connections to overcome apoptosis-resistance. Cancer Biol Ther 2005; 4: 391-392.
12. Hajji N, Wallenborg K, Vlachos P, Nyman U, Hermanson O, Joseph B. Combinatorial action of the HDAC inhibitor trichostatin A and etoposide induces caspase -mediated AIF-dependent apoptotic cell death in non-small cell lung carcinoma cells. Oncogene 2008; 27: 3134-3144.
13. Wu J, Hu CP, Gu QH, Li YP, Song M. Trichostatin A sensitizes cisplatin-resistant A549 cells to apoptosis by up-regulating death-associated protein kinase. Acta Pharmacol Sin 2010; 31: 93-101.
14. Kanzaki M, Kakinuma H, Kumazawa T etal. Low concentrations of the histone deacetylase inhibitor, depsipeptide, enhance the effects of gemcitabine and docetaxel in hormone refractory prostate cancer cells. Oncol Rep 2007; 17: 761-767.
15. Zhang X, Yashiro M, Ren J, Hirakawa K. Histone deacetylase inhibitor, trichostatin A, increases the chemosensitivity of anticancer drugs in gastric cancer cell lines. Oncol Rep 2006; 16: 563-568.
16. Chang H, Jeung HC, Jung JJ, Kim TS, Rha SY, Chung HC. Identification of genes associated with chemo- sensitivity to SAHA/taxane combination treatment in taxane-resistant breast cancer cells. Breast Cancer Res Treat 2011; 125: 55-63.
17. Zhang QC, Jiang SJ, Zhang S, Ma XB. Histone deacetylase inhibitor trichostatin A enhances anti-tumor effects of docetaxel or erlotinib in A549 cell line. Asian Pac J Cancer Prev 2012; 13: 3471-3476.
18. Wu J, Hu C. [Trichostatin A induced Bcl-2 protein level decrease mediated A549/CDDP cells apoptosis by mitochondria pathway.] Zhongguo Fei Ai Za Zhi 2009; 12: 1143-1149. (In Chinese.)
19. Choi YH. Induction of apoptosis by trichostatin A, a histone deacetylase inhibitor, is associated with inhibition of cyclooxygenase-2 activity in human non-small cell lung cancer cells. Int J Oncol 2005; 27: 473-479.
20. Liu T, Zhang M, Zhang H etal. Combined antitumor activity of cucurbitacin B and docetaxel in laryngeal cancer. Eur J Pharmacol 2008; 587: 78-84.
21. Sharp DA, Lawrence DA, Ashkenazi A. Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis. J Biol Chem 2005; 280: 19401-19409.
22. Ghavami S, Hashemi M, Ande SR etal. Apoptosis and cancer: mutations within caspase genes. J Med Genet 2009; 46: 497-510.