Identification of PSEN1 mutations p.M233L and p.R352C in Han Chinese families with early-onset familial Alzheimer's disease

Neurobiology of Aging

Volumn 36, Issue 3, 2015, Pages 1602.e3-1602.e6

  Jiang, Hong Yan ^a,b   Li, Guo Dong ^c,d   Dai, Shao Xing ^c,d   Bi, Rui ^c,d   Zhang, Deng Feng ^c,d   Li, Zong Fang ^b   Xu, Xiu Feng ^b   Zhou, Tai Cheng ^a,c   Yu, Li ^a   Yao, Yong Gang ^c,d,e  

^a YUNNAN UNIVERSITY   (China)

^b KUNMING MEDICAL UNIVERSITY   (China)

^c KUNMING INSTITUTE OF ZOOLOGY   (China)

^d UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^e INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Chinese; Early onset familial Alzheimer's disease; Mutation; PSEN1

Indexed keywords

AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; PRESENILIN 1; PRESENILIN 2; PSEN1 PROTEIN, HUMAN; PSEN2 PROTEIN, HUMAN;

ADULT; AGED; ALZHEIMER DISEASE; APOE GENE; ARTICLE; CHILD; CHRONIC DISEASE; CLINICAL ASSESSMENT; DEMENTIA; DISEASE ASSOCIATION; DISEASE COURSE; EARLY ONSET FAMILIAL ALZHEIMER DISEASE; EXON; FAMILIAL DISEASE; FEMALE; GENE; GENE IDENTIFICATION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC SCREENING; HAN CHINESE; HUMAN; MALE; MENTAL DISEASE; NEUROLOGIC DISEASE; ONSET AGE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PSEN1 GENE; VERY ELDERLY; ASIAN CONTINENTAL ANCESTRY GROUP; DOMINANT GENE; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; MUTATION; PEDIGREE;

ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ASIAN CONTINENTAL ANCESTRY GROUP; CHILD; DEMENTIA; DISEASE PROGRESSION; FEMALE; GENES, DOMINANT; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; HUMANS; MALE; MIDDLE AGED; MUTATION; PEDIGREE; PHENOTYPE; PRESENILIN-1; PRESENILIN-2;

EID: 84923543053     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.11.009     Document Type: Article

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