QSAR model as a random event: A case of rat toxicity

Bioorganic and Medicinal Chemistry

Volumn 23, Issue 6, 2015, Pages 1223-1230

  Toropova, Alla P ^a   Toropov, Andrey A ^a   Benfenati, Emilio ^a   Leszczynska, Danuta ^b   Leszczynski, Jerzy ^c  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b Jackson State University   (United States)

^c JACKSON STATE UNIVERSITY   (United States)

Author keywords

CORAL software; Domain of applicability; Oral rat toxicity; QSAR; Validation

Indexed keywords

AROMATIC COMPOUND; CARBON; HYDROGEN; NITROGEN; OXYGEN; PHOSPHORUS; SULFUR; ORGANIC COMPOUND;

ARTICLE; COMPUTER PREDICTION; COMPUTER PROGRAM; MATHEMATICAL MODEL; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; RELIABILITY; REPRODUCIBILITY; TOXICITY TESTING; VALIDATION STUDY; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; LD50;

RATTUS;

ANIMALS; LETHAL DOSE 50; MODELS, MOLECULAR; ORGANIC CHEMICALS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS; REPRODUCIBILITY OF RESULTS; SOFTWARE;

EID: 84923540970     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2015.01.055     Document Type: Article

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