Efficient bone formation in a swine socket lift model using escherichia coli-derived recombinant human bone morphogenetic protein-2 adsorbed in β-tricalcium phosphate

Cells Tissues Organs

Volumn 199, Issue 4, 2014, Pages 249-255

  Ono, Mitsuaki ^a   Sonoyama, Wataru ^a   Yamamoto, Katushi ^b   Oida, Yasutaka ^a   Akiyama, Kentaro ^a   Shinkawa, Shigehiko ^a   Nakajima, Ryu ^a   Pham, Hai T ^a   Hara, Emilio S ^a   Kuboki, Takuo ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b GC Corporation   (Japan)

Author keywords

Biomaterials; Bone density; Bone regeneration; Bone to implant contact; Escherichia coli derived recombinant human bone morphogenetic protein 2; Implant; Sinus lift; Surgery; Tricalcium phosphate

Indexed keywords

BETA CALCIUM PHOSPHATE; CALCIUM PHOSPHATE; ESCHERICHIA COLI RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; UNCLASSIFIED DRUG; BETA-TRICALCIUM PHOSPHATE; BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2; RECOMBINANT PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEFECT; BONE DENSITY; BONE REGENERATION; BONE TO IMPLANT CONTACT; CLINICAL EFFECTIVENESS; CLINICAL EVALUATION; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ADSORPTION; DRUG DETERMINATION; ESCHERICHIA COLI; HISTOPATHOLOGY; MALE; MAXILLARY SINUS; MOLECULAR STABILITY; MUSCULOSKELETAL SYSTEM PARAMETERS; NONHUMAN; NOSE MUCOSA; OSSIFICATION; PRIORITY JOURNAL; SWINE; TOOTH IMPLANT; TOOTH SOCKET; ANIMAL; BONE DEVELOPMENT; DRUG EFFECTS; HUMAN; METABOLISM; PATHOGENICITY; PIG;

ANIMALIA; ESCHERICHIA; ESCHERICHIA COLI; MAMMALIA; SUIDAE;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; BONE REGENERATION; CALCIUM PHOSPHATES; ESCHERICHIA COLI; HUMANS; MALE; OSTEOGENESIS; RECOMBINANT PROTEINS; SWINE; TRANSFORMING GROWTH FACTOR BETA;

EID: 84923530614     PISSN: 14226405     EISSN: 14226421     Source Type: Journal    
DOI: 10.1159/000369061     Document Type: Article

References (20)

1. Choi, Y., J.H. Yun, C.S. Kim, S.H. Choi, J.K. Chai, U.W. Jung (2012) Sinus augmentation using absorbable collagen sponge loaded with Escherichia coli-expressed recombinant human bone morphogenetic protein 2 in a standardized rabbit sinus model: a radiographic and histologic analysis. Clin Oral Implants Res 23: 682-689
2. Delloye, C., O. Cornu, V. Druez, O. Barbier (2007) Bone allografts: what they can offer and what they cannot. J Bone Joint Surg Br 89: 574-579
3. Deppe, H., T. Mucke, S. Wagenpfeil, F. Holzle (2012) Sinus augmentation with intra-versus extraorally harvested bone grafts for the provision of dental implants: clinical long-term results. Quintessence Int 43: 469-481
4. Gutwald, R., J. Haberstroh, A. Stricker, E. Ruther, F. Otto, S.P. Xavier, T. Oshima, E. Marukawa, I. Seto, S. Enomoto, C.F. Hoogendijk, R. Schmelzeisen, S. Sauerbier (2010) Influence of rhBMP-2 on bone formation and osseointegration in different implant systems after sinus-floor elevation: an in vivo study on sheep. J Craniomaxillofac Surg 38: 571-579
5. Han, J., M. Lulic, N.P. Lang (2010) Factors influencing resonance frequency analysis assessed by Osstell mentor during implant tissue integration. 2. Implant surface modifications and implant diameter. Clin Oral Implants Res 21: 605-611
6. Hanisch, O., D.N. Tatakis, M.D. Rohrer, P.S. Wohrle, J.M. Wozney, U.M. Wikesjo (1997) Bone formation and osseointegration stimulated by rhBMP-2 following subantral augmentation procedures in nonhuman primates. Int J Oral Maxillofac Implants 12: 785-792
7. Huh, J.B., S.E. Kim, H.E. Kim, S.S. Kang, K.H. Choi, C.M. Jeong, J.Y. Lee, S.W. Shin (2012) Effects of anodized implants coated with Escherichia coli-derived rhBMP-2 in beagle dogs. Int J Oral Maxillofac Surg 41: 1577-1584
8. Huh, J.B., C.K. Park, S.E. Kim, K.M. Shim, K.H. Choi, S.J. Kim, J.S. Shim, S.W. Shin (2011) Alveolar ridge augmentation using anodized implants coated with Escherichia coli-derived recombinant human bone morphogenetic protein 2. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 112: 42-49
9. Jensen, O.T., L.B. Shulman, M.S. Block, V.J. Iacono (1998) Report of the Sinus Consensus Conference of 1996. Int J Oral Maxillofac Implants 13: 11-45
10. Khan, S.N., J.M. Lane (2004) The use of recombinant human bone morphogenetic protein-2 (rhBMP-2) in orthopaedic applications. Expert Opin Biol Ther 4: 741-748
11. Kubler, N.R., J.F. Reuther, G. Faller, T. Kirchner, R. Ruppert, W. Sebald (1998) Inductive properties of recombinant human BMP-2 produced in a bacterial expression system. Int J Oral Maxillofac Surg 27: 305-309
12. Lee, J.K., L.R. Cho, H.S. Um, B.S. Chang, K.S. Cho (2013) Bone formation and remodeling of three different dental implant surfaces with Escherichia coli-derived recombinant human bone morphogenetic protein 2 in a rabbit model. Int J Oral Maxillofac Implants 28: 424-430
13. Ng, V.Y. (2012) Risk of disease transmission with bone allograft. Orthopedics 35: 679-681
14. Ono, M., W. Sonoyama, K. Nema, E.S. Hara, Y. Oida, P.T. Hai, K. Yamamoto, K. Hirota, K. Sugama, W. Sebald, T. Kuboki (2013) Regeneration of calvarial defects with Escherichia coli-derived rhBMP-2 adsorbed in PLGA membrane. Cells Tissues Organs 198: 367-376
15. Schliephake, H. (2013) Clinical efficacy of growth factors to enhance tissue repair in oral and maxillofacial reconstruction: a systematic review. Clin Implant Dent Relat Res DOI: 10.1111/cid.12114
16. Uckan, S., K. Deniz, E. Dayangac, K. Araz, B.H. Ozdemir (2010) Early implant survival in posterior maxilla with or without beta-tricalcium phosphate sinus floor graft. J Oral Maxillofac Surg 68: 1642-1645
17. Wang, Z., Z. Guo, H. Bai, J. Li, X. Li, G. Chen, J. Lu (2013) Clinical evaluation of beta-TCP in the treatment of lacunar bone defects: a prospective, randomized controlled study. Mater Sci Eng C Mater Biol Appl 33: 1894-1899
18. Yamada, M., M. Shiota, Y. Yamashita, S. Kasugai (2007) Histological and histomorphometrical comparative study of the degradation and osteoconductive characteristics of alpha-and beta-tricalcium phosphate in block grafts. J Biomed Mater Res B Appl Biomater 82: 139-148
19. Yano, K., M. Hoshino, Y. Ohta, T. Manaka, Y. Naka, Y. Imai, W. Sebald, K. Takaoka (2009) Osteoinductive capacity and heat stability of recombinant human bone morphogenetic protein-2 produced by Escherichia coli and dimerized by biochemical processing. J Bone Miner Metab 27: 355-363
20. Zhang, D., F. Chu, Y. Yang, L. Xia, D. Zeng, H. Uludag, X. Zhang, Y. Qian, X. Jiang (2011) Orthodontic tooth movement in alveolar cleft repaired with a tissue engineering bone: an experimental study in dogs. Tissue Eng Part A 17: 1313-1325