Plasma soluble lectin-like oxidized low-density lipoprotein receptor-1 as a novel prognostic biomarker in patients with ST-segment elevation acute myocardial infarction

Circulation Journal

Volumn 79, Issue 3, 2015, Pages 641-648

  Higuma, Takumi ^a   Abe, Naoki ^a   Tateyama, Syunta ^a   Endo, Tomohide ^a   Shibutani, Shuji ^a   Yokoyama, Hiroaki ^a   Hanada, Kenji ^a   Yamada, Masahiro ^a   Tomita, Hirofumi ^a   Hanada, Hiroyuki ^a   Osanai, Tomohiro ^a   Kume, Noriaki ^b   Okumura, Ken ^a  

^a HIROSAKI UNIVERSITY   (Japan)

^b KOBE GAKUIN UNIVERSITY   (Japan)

Author keywords

Acute coronary syndrome; Biomarkers; Soluble lectin like oxidized low density lipoprotein receptor 1 (sLOX 1); ST segment elevation acute myocardial infarction (STEMI)

Indexed keywords

BIOLOGICAL MARKER; CREATINE KINASE; CREATINE KINASE MB; GLUCOSE; HEMOGLOBIN A1C; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; TROPONIN T; OLR1 PROTEIN, HUMAN;

AGED; ANGIOCARDIOGRAPHY; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; CHEMILUMINESCENCE IMMUNOASSAY; CORONARY ARTERY OCCLUSION; CORONARY REPERFUSION; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE SEVERITY; ELECTROCARDIOGRAPHY; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART RUPTURE; HEART VENTRICULOGRAPHY; HUMAN; KAPLAN MEIER METHOD; LIMIT OF DETECTION; LIPID ANALYSIS; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; MULTIVARIATE ANALYSIS; OBSERVATIONAL STUDY; PERCUTANEOUS CORONARY INTERVENTION; PROGNOSIS; PROSPECTIVE STUDY; RECURRENT DISEASE; SENSITIVITY AND SPECIFICITY; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; TELEPHONE INTERVIEW; THORAX PAIN; TRANSTHORACIC ECHOCARDIOGRAPHY; UNIVARIATE ANALYSIS; BLOOD; MIDDLE AGED; MORTALITY; MYOCARDIAL INFARCTION; VERY ELDERLY;

AGED; AGED, 80 AND OVER; BIOMARKERS; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PERCUTANEOUS CORONARY INTERVENTION; PROSPECTIVE STUDIES; SCAVENGER RECEPTORS, CLASS E;

EID: 84923438691     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-14-0904     Document Type: Article

References (28)

1. Libby P. Current concepts of the pathogenesis of the acute coronary syndromes. Circulation 2001; 104: 365–372.
2. Falk E, Shah PK, Fuster V. Coronary plaque disruption. Circulation 1995; 92: 657–671.
3. Ross R. Atherosclerosis: An inflammatory disease. N Engl J Med 1999; 340: 115–126.
4. Steinberg D. Lewis A: Conner Memorial Lecture: Oxidative modification of LDL and atherogenesis. Circulation 1997; 95: 1062–1071.
5. Norata GD, Tonti L, Roma P, Catapano AL. Apoptosis and proliferation of endothelial cells in early atherosclerotic lesions: Possible role of oxidized LDL. Nutr Metab Cardiovasc Dis 2002; 12: 297–305.
6. Sawamura T, Kume N, Aoyama T, Moriwaki H, Hoshikawa H, Aiba Y, et al. An endothelial receptor for oxidized low-density lipoprotein. Nature 1997; 386: 73–77.
7. Kataoka H, Kume N, Miyamoto S, Minami M, Morimoto M, Hayashida K, et al. Oxidized LDL modulates Bax/Bcl-2 through the lectin like Ox-LDL receptor-1 in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 2001; 21: 955–960.
8. Kume N, Kita T. Apoptosis of vascular cells by oxidized LDL: Involvement of caspases and LOX-1, and its implication in atherosclerotic plaque rupture. Circ Res 2004; 94: 269–270.
9. Li D, Liu L, Chen H, Sawamura T, Ranganathan S, Mehta JL. LOX-1 mediates oxidized low-density lipoprotein-induced expression of matrix metalloproteinases in human coronary artery endothelial cells. Circulation 2003; 107: 612–617.
10. Kume N, Murase T, Moriwaki H, Aoyama T, Sawamura T, Masaki T, et al. Inducible expression of lectin-like oxidized LDL receptor-1 in vascular endothelial cells. Circ Res 1998; 83: 322–327.
11. Kataoka H, Kume N, Miyamoto S, Minami M, Moriwaki H, Murase T, et al. Expression of lectin like oxidized low-density lipoprotein receptor-1 in human atherosclerotic lesions. Circulation 1999; 99: 3110–3117.
12. Murase T, Kume N, Kataoka H, Minami M, Sawamura T, Masaki T, et al. Identification of soluble forms of lectin-like oxidized LDL receptor-1. Arterioscler Thromb Vasc Biol 2000; 20: 715–720.
13. Hayashida K, Kume N, Murase T, Minami M, Nakagawa D, Inada T, et al. Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels are elevated in acute coronary syndrome: A novel marker for early diagnosis. Circulation 2005; 112: 812–818.
14. Kume N, Mitsuoka H, Hayashida K, Tanaka M, Kita T. Soluble lectin-like oxidized low-density lipoprotein receptor-1 predicts prognosis after acute coronary syndrome: A pilot study. Circ J 2010; 74: 1399–1404.
15. Nakamura M, Ohta H, Kume N, Hayashida K, Tanaka M, Mitsuoka H, et al. Generation of monoclonal antibodies against a soluble form of lectin-like oxidized low-density lipoprotein receptor-1 and development of a sensitive chemiluminescent enzyme immunoassay. J Pharm Biomed Anal 2010; 51: 158–163.
16. Kojima S, Matsui K, Ogawa H, Kumamoto Acute Coronary Events (KACE) Study Group. Temporal trends in hospitalization for acute myocardial infarction between 2004 and 2011 in Kumamoto, Japan. Circ J 2013; 77: 2841–2843.
17. Hao K, Yasuda S, Takii T, Ito Y, Takahashi J, Ito K, et al. Urbanization, life style changes and the incidence/in-hospital mortality of acute myocardial infarction in Japan: Report from the MIYAGI-AMI Registry Study. Circ J 2012; 76: 1136–1144.
18. Nakatani D, Sakata Y, Suna S, Usami M, Matsumoto S, Shimizu M, et al. Incidence, predictors, and subsequent mortality risk of recurrent myocardial infarction in patients following discharge for acute myocardial infarction. Circ J 2013; 77: 439–446.
19. Daida H, Miyauchi K, Ogawa H, Yokoi H, Matsumoto M, Kitakaze M, et al. Management and two-year long-term clinical outcome of acute coronary syndrome in Japan: Prevention of atherothrombotic incidents following ischemic coronary attack (PACIFIC) registry. Circ J 2013; 77: 934–943.
20. Kobayashi N, Takano M, Hata N, Kume N, Yamamoto M, Yokoyama S, et al. Soluble lectin-like oxidized LDL receptor-1 (sLOX-1) as a valuable diagnostic marker for rupture of thin-cap fibroatheroma: Verification by optical coherence tomography. Int J Cardiol 2013; 168: 3217–3223.
21. Kobayashi N, Hata N, Kume N, Shinada T, Tomita K, Shirakabe A, et al. Soluble lectin-like oxidized LDL receptor-1 and high-sensitivity troponin T as diagnostic biomarkers for acute coronary syndrome: Improved values with combination usage in emergency rooms. Circ J 2011; 75: 2862–2871.
22. Takaya T, Wada H, Morimoto T, Sunagawa Y, Kawamura T, Takanabe-Mori R, et al. Left ventricular expression of lectin-like oxidized low-density lipoprotein receptor-1 in failing rat hearts. Circ J 2010; 74: 723–729.
23. Iwai-Kanai E, Hasegawa K, Sawamura T, Fujita M, Yanazuma T, Toyokuni S, et al. Activation of lectin-like oxidized low-density lipoprotein receptor-1 induces apoptosis in cultured neonatal rat cardiac myocytes. Circulation 2001; 104: 2948–2954.
24. Kataoka K, Hasegawa K, Sawamura T, Fujita M, Yanazume T, Toyokuni S, et al. LOX-1 pathway affects the extent of myocardial ischemia-reperfusion injury. Biochem Biophys Res Commun 2003; 300: 656–660.
25. Li L, Sawamura T, Renier G. Glucose enhances endothelial LOX-1 expression: Role for LOX-1 in glucose-induced human monocyte adhesion to endothelium. Diabetes 2003; 52: 1843–1850.
26. Draude G, Hrboticky N, Lorenz RL. The expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1) on human vascular smooth muscle cells and monocytes and its down-regulation by lovastatin. Biochem Pharmacol 1999; 57: 383–386.
27. Hofnagel O, Luechtenborg B, Eschert H, Weissen-Plenz G, Severs NJ, Robenek H. Pravastatin inhibits expression of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in Watanabe heritable hyperlipidemic rabbits: A new pleiotropic effect of statins. Arterioscler Thromb Vasc Biol 2006; 26: 604–610.
28. Li DY, Zhang YC, Philips MI, Sawamura T, Mehta JL. Upregulation of endothelial receptor for oxidized low-density lipoprotein (LOX-1) in cultured human coronary artery endothelial cells by angiotensin II type 1 receptor activation. Circ Res 1999; 84: 1043–1049.