The association between the rs6495309 polymorphism in CHRNA3 gene and lung cancer risk in Chinese: A meta-analysis

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Xiao, Min ^a,b   Chen, Lei ^a,b   Wu, Xiaoling ^a,b   Wen, Fuqiang ^a,b  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINIC RECEPTOR; NICOTINIC RECEPTOR SUBUNIT ALPHA3;

GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HUMAN; LUNG TUMOR; META ANALYSIS; PATHOLOGY; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LUNG NEOPLASMS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, NICOTINIC; RISK FACTORS;

EID: 84923385141     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep06372     Document Type: Article

References (28)

1. Chen, W. J. et al. Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling. Nat Commun. 5, 3472 (2014).
2. Chen, Z. et al. Role of the stem cell-associated intermediate filament nestin in malignant proliferation of non-small cell lung cancer. PLoS One. 9, e85584 (2014).
3. Zhu, X., Fan, W. & Li, D. Intronic boundary mutation rs430397 cannot affect alternate splicing and is an indecisive risk factor for non-small cell lung cancer. Chest. 142, 1691-1692 (2012).
4. Uzunoglu, F. G. et al. The T393C polymorphism of GNAS1 is a predictor for relapse and survival in resectable non-small cell lung cancer. Lung Cancer. 79, 151-155 (2013).
5. Coskunpinar, E. et al. The significance of HSP90AA1, HSP90AB1 and HSP90B1 gene polymorphisms in a Turkish population with non-small cell lung cancer. Anticancer Res. 34, 753-757 (2014).
6. Yoo, S. S. et al. Replication of results of a genome-wide association study on lung cancer survival in a Korean population. Cancer Genet. 207, 35-39 e32 (2014).
7. Li, W., Li, K., Zhao, L. & Zou, H. DNA repair pathway genes and lung cancer susceptibility: A meta-analysis. Gene. 538, 361-365 (2014).
8. Timofeeva, M. N. et al. Genetic polymorphisms in 15q25 and 19q13 loci, cotinine levels, and risk of lung cancer in EPIC. Cancer Epidemiol Biomarkers Prev. 20, 2250-2261 (2011).
9. Wassenaar, C. A. et al. Relationship between CYP2A6 and CHRNA5-CHRNA3- CHRNB4 variation and smoking behaviors and lung cancer risk. J Natl Cancer Inst. 103, 1342-1346 (2011).
10. Saccone, N. L. et al. Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet. 6 (2010).
11. Hung, R. J. et al. A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature. 452, 633-637 (2008).
12. Amos, C. I. et al. Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet. 40, 616-622 (2008).
13. Shen, B. et al. Association between CHRNA3 gene polymorphisms and lung cancer risk. Zhong Hua Zhong Liu Fang Zhi Za Zhi. 21, 252-255 (2014).
14. Yang, L. et al. Association between the genetic variant in CHRNA3 promoter and lung cancer risk in passive smoking population. Zhong Hua Zhong Liu Fang Zhi Za Zhi 17, 972-975 (2010).
15. Niu, X. M. Polymorphism of nicotinic acetylcholine receptor subunit CHRNA3- CHRNA4-CHRNA5 gene cluster on 15q25 in lung cancer of Chinese Han population, (2009). Available at: http://d.wanfangdata.com.cn/Thesis-D070401. aspx. (Date of access: 30/05/2014).
16. Wu,W. et al.GSTM1 and GSTT1 null polymorphisms and male infertility risk: an updated meta-analysis encompassing 6934 subjects. Sci Rep. 3, 2258 (2013).
17. Zhou, H. et al. Genetic polymorphism of matrix metalloproteinase family and chronic obstructive pulmonary disease susceptibility: a meta-analysis. Sci Rep. 3, 2818 (2013).
18. Li, Y. Y. et al. CDKAL1 gene rs7756992 A/G polymorphism and type 2 diabetes mellitus: a meta-analysis of 62,567 subjects. Sci Rep. 3, 3131 (2013).
19. Wu, C. et al. Genetic variants on chromosome 15q25 associated with lung cancer risk in Chinese populations. Cancer Res. 69, 5065-5072 (2009).
20. Yang, L. et al. Functional polymorphisms of CHRNA3 predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese. PLoS One. 7, e46071 (2012).
21. Du, M. CHRNA3 gene promoter polymorphism with COPD and lung cancer susceptibility in smokers, (2011). Available at: http://d.wanfangdata.com.cn/ Thesis-Y2238253.aspx. (Date of access: 30/05/2014).
22. Wu, G. D., Lai, E. J., Huang, N. &Wen, X. Oct-1 and CCAAT/enhancer-binding protein (C/EBP) bind to overlapping elements within the interleukin-8 promoter. The role of Oct-1 as a transcriptional repressor. J Biol Chem. 272, 2396-2403 (1997).
23. Wang, W. et al. MDM2 SNP309 polymorphism is associated with colorectal cancer risk. Sci Rep. 4, 4851 (2014).
24. Liu, M., Bian, C., Zhang, J. &Wen, F. Apolipoprotein E gene polymorphism and Alzheimer's disease in Chinese population: a meta-analysis. Sci Rep. 4, 4383 (2014).
25. Hu, Y. et al.MicroRNA sequence polymorphisms and the risk of different types of cancer. Sci Rep. 4, 3648 (2014).
26. Tang, C. et al. CCND1 G870A polymorphism and risk for head and neck cancer: a meta-analysis. Med Oncol. 28, 1319-1324 (2011).
27. Zheng, Z., Li, X., Li, Z. &Ma, X. C. IL-4 -590C/T polymorphism and susceptibility to liver disease: a meta-analysis and meta-regression. DNA Cell Biol. 32, 443-450 (2013).
28. Gu,M. et al. Strong association between two polymorphisms on 15q25.1 and lung cancer risk: a meta-analysis. PLoS One. 7, e37970 (2012).