메뉴 건너뛰기




Volumn 5, Issue , 2014, Pages

Comparative analysis of KRAS codon 12, 13, 18, 61, and 117 mutations using human MCF10A isogenic cell lines

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE; RAS PROTEIN;

EID: 84923348272     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep08535     Document Type: Article
Times cited : (105)

References (33)
  • 1
    • 45449092590 scopus 로고    scopus 로고
    • Snap shot: Ras signaling
    • Cully, M. & Downward, J. Snap Shot: Ras Signaling. Cell 133, 1292-1292.e1 (2008).
    • (2008) Cell , vol.133 , pp. e1
    • Cully, M.1    Downward, J.2
  • 3
    • 34248591612 scopus 로고    scopus 로고
    • Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
    • Roberts, P. J. & Der, C. J. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 26, 3291-3310 (2007).
    • (2007) Oncogene , vol.26 , pp. 3291-3310
    • Roberts, P.J.1    Der, C.J.2
  • 4
    • 0037805547 scopus 로고    scopus 로고
    • RAS oncogenes: The first 30 years
    • Malumbres, M. & Barbacid, M. RAS oncogenes: the first 30 years. Nat Rev Cancer 3, 459-465 (2003).
    • (2003) Nat Rev Cancer , vol.3 , pp. 459-465
    • Malumbres, M.1    Barbacid, M.2
  • 5
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • Downward, J. Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 3, 11-22 (2003).
    • (2003) Nat Rev Cancer , vol.3 , pp. 11-22
    • Downward, J.1
  • 6
    • 84878401236 scopus 로고    scopus 로고
    • Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling
    • Zimmermann, G. et al. Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling. Nature 497, 638-642 (2013).
    • (2013) Nature , vol.497 , pp. 638-642
    • Zimmermann, G.1
  • 7
    • 84888639050 scopus 로고    scopus 로고
    • K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
    • Ostrem, J. M., Peters, U., Sos, M. L., Wells, J. A. & Shokat, K. M. K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature 503, 548-551 (2013).
    • (2013) Nature , vol.503 , pp. 548-551
    • Ostrem, J.M.1    Peters, U.2    Sos, M.L.3    Wells, J.A.4    Shokat, K.M.5
  • 8
    • 78149249388 scopus 로고    scopus 로고
    • Personalized medicine in non-small-cell lung cancer: Is KRAS a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy?
    • Roberts, P. J., Stinchcombe, T. E., Der, C. J. & Socinski, M. A. Personalized medicine in non-small-cell lung cancer: is KRAS a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy? J Clin Oncol 28, 4769-4777 (2010).
    • (2010) J Clin Oncol , vol.28 , pp. 4769-4777
    • Roberts, P.J.1    Stinchcombe, T.E.2    Der, C.J.3    Socinski, M.A.4
  • 9
    • 77949435827 scopus 로고    scopus 로고
    • Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer
    • Bardelli, A. & Siena, S. Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer. J Clin Oncol 28, 1254-1261 (2010).
    • (2010) J Clin Oncol , vol.28 , pp. 1254-1261
    • Bardelli, A.1    Siena, S.2
  • 10
    • 3843084078 scopus 로고    scopus 로고
    • The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website
    • Bamford, S. et al. The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website. Br J Cancer 91, 355-358 (2004).
    • (2004) Br J Cancer , vol.91 , pp. 355-358
    • Bamford, S.1
  • 11
    • 0034548712 scopus 로고    scopus 로고
    • K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorage-independent growth than codon 13 mutation or proto-oncogene overexpression
    • Guerrero, S. et al. K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorage-independent growth than codon 13 mutation or proto-oncogene overexpression. Cancer Res 60, 6750-6756 (2000).
    • (2000) Cancer Res , vol.60 , pp. 6750-6756
    • Guerrero, S.1
  • 12
    • 77955046517 scopus 로고    scopus 로고
    • Genomic and biological characterization of exon 4 KRAS mutations in human cancer
    • Janakiraman, M. et al. Genomic and biological characterization of exon 4 KRAS mutations in human cancer. Cancer Res 70, 5901-5911 (2010).
    • (2010) Cancer Res , vol.70 , pp. 5901-5911
    • Janakiraman, M.1
  • 13
    • 78049341541 scopus 로고    scopus 로고
    • Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab
    • De Roock, W. et al. Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab. JAMA 304, 1812-1820 (2010).
    • (2010) JAMA , vol.304 , pp. 1812-1820
    • De Roock, W.1
  • 14
    • 84885755854 scopus 로고    scopus 로고
    • Association KRAS G13D tumor mutated outcome in patients with chemotherapy refractory metastatic colorectal cancer treated with cetuximab
    • Tural, D. et al. Association KRAS G13D tumor mutated outcome in patients with chemotherapy refractory metastatic colorectal cancer treated with cetuximab. Hepatogastroenterology 60, 1035-1040 (2013).
    • (2013) Hepatogastroenterology , vol.60 , pp. 1035-1040
    • Tural, D.1
  • 15
    • 0037115610 scopus 로고    scopus 로고
    • Amplification of wild-type Kras promotes growth of head and neck squamous cell carcinoma
    • Hoa, M., Davis, S. L., Ames, S. J. & Spanjaard, R. A. Amplification of wild-type Kras promotes growth of head and neck squamous cell carcinoma. Cancer Res 62, 7154-7156 (2002).
    • (2002) Cancer Res , vol.62 , pp. 7154-7156
    • Hoa, M.1    Davis, S.L.2    Ames, S.J.3    Spanjaard, R.A.4
  • 16
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • Debnath, J., Muthuswamy, S. K. & Brugge, J. S. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 30, 256-268 (2003).
    • (2003) Methods , vol.30 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3
  • 17
    • 84901979739 scopus 로고    scopus 로고
    • Oncogene-like induction of cellular invasion from centrosome amplification
    • Godinho, S. A. et al. Oncogene-like induction of cellular invasion from centrosome amplification. Nature 510, 167-171 (2014).
    • (2014) Nature , vol.510 , pp. 167-171
    • Godinho, S.A.1
  • 18
    • 34548710863 scopus 로고    scopus 로고
    • Knock-in of Mutant K-ras in Nontumorigenic Human Epithelial Cells as a New Model for Studying K-ras Mediated Transformation
    • Konishi, H. et al. Knock-in of Mutant K-ras in Nontumorigenic Human Epithelial Cells as a New Model for Studying K-ras Mediated Transformation. Cancer Res 67, 8460-8467 (2007).
    • (2007) Cancer Res , vol.67 , pp. 8460-8467
    • Konishi, H.1
  • 19
    • 34347242470 scopus 로고    scopus 로고
    • RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation
    • Roux, P. P. et al. RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. J Biol Chem 282, 14056-14064 (2007).
    • (2007) J Biol Chem , vol.282 , pp. 14056-14064
    • Roux, P.P.1
  • 20
    • 79952155325 scopus 로고    scopus 로고
    • New insights into oncogenic stress
    • Haigis, K. M. & Sweet-Cordero, A. New insights into oncogenic stress. Nat Genet 43, 177-178 (2011).
    • (2011) Nat Genet , vol.43 , pp. 177-178
    • Haigis, K.M.1    Sweet-Cordero, A.2
  • 21
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelialmesenchymal transitions
    • Thiery, J. P. & Sleeman, J. P. Complex networks orchestrate epithelialmesenchymal transitions. Nat Rev Mol Cell Biol 7, 131-142 (2006).
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 22
    • 0025129726 scopus 로고
    • Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10
    • Soule, H. D. et al. Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res 50, 6075-6086 (1990).
    • (1990) Cancer Res , vol.50 , pp. 6075-6086
    • Soule, H.D.1
  • 23
    • 31044441241 scopus 로고    scopus 로고
    • Gene expression profiling of breast cell lines identifies potential new basal markers
    • Charafe-Jauffret, E. et al. Gene expression profiling of breast cell lines identifies potential new basal markers. Oncogene 25, 2273-2284 (2005).
    • (2005) Oncogene , vol.25 , pp. 2273-2284
    • Charafe-Jauffret, E.1
  • 24
    • 44849114353 scopus 로고    scopus 로고
    • Subtypes of breast cancer show preferential site of relapse
    • Smid, M. et al. Subtypes of Breast Cancer Show Preferential Site of Relapse. Cancer Res 68, 3108-3114 (2008).
    • (2008) Cancer Res , vol.68 , pp. 3108-3114
    • Smid, M.1
  • 25
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sorlie, T. et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 98, 10869-10874 (2001).
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10869-10874
    • Sorlie, T.1
  • 26
    • 35248889408 scopus 로고    scopus 로고
    • EGFR associated expression profiles vary with breast tumor subtype
    • Hoadley, K. A. et al. EGFR associated expression profiles vary with breast tumor subtype. BMC Genomics 8, 258 (2007).
    • (2007) BMC Genomics , vol.8 , pp. 258
    • Hoadley, K.A.1
  • 27
    • 40849114627 scopus 로고    scopus 로고
    • Oncogenic ras-induced expression of cytokines: A new target of anti-cancer therapeutics
    • Ancrile, B. B., O'Hayer, K. M. & Counter, C. M. Oncogenic ras-induced expression of cytokines: a new target of anti-cancer therapeutics. Mol Interv 8, 22-27 (2008).
    • (2008) Mol Interv , vol.8 , pp. 22-27
    • Ancrile, B.B.1    O'Hayer, K.M.2    Counter, C.M.3
  • 28
    • 33750798741 scopus 로고    scopus 로고
    • The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis
    • Yang, G. et al. The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis. Proc Natl Acad Sci USA 103, 16472-16477 (2006).
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 16472-16477
    • Yang, G.1
  • 29
    • 33646255924 scopus 로고    scopus 로고
    • High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras
    • Wislez, M. et al. High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras. Cancer Res 66, 4198-4207 (2006).
    • (2006) Cancer Res , vol.66 , pp. 4198-4207
    • Wislez, M.1
  • 30
    • 84901844623 scopus 로고    scopus 로고
    • Clinicopathological and prognostic significance of interleukin-8 expression and its relationship to KRAS mutation in lung adenocarcinoma
    • Sunaga, N. et al. Clinicopathological and prognostic significance of interleukin-8 expression and its relationship to KRAS mutation in lung adenocarcinoma. Br J Cancer 110, 2047-2053 (2014).
    • (2014) Br J Cancer , vol.110 , pp. 2047-2053
    • Sunaga, N.1
  • 31
    • 84897142154 scopus 로고    scopus 로고
    • BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling
    • ra30
    • Sanchez-Laorden, B. et al. BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling. Sci Signal 7, ra30 (2014).
    • (2014) Sci Signal , vol.7
    • Sanchez-Laorden, B.1
  • 32
    • 65849111219 scopus 로고    scopus 로고
    • Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells
    • Scholl, C. et al. Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells. Cell 137, 821-834 (2009).
    • (2009) Cell , vol.137 , pp. 821-834
    • Scholl, C.1
  • 33
    • 0141924536 scopus 로고    scopus 로고
    • Development of a real-time RT-PCR assay for the quantification of the most frequent MLL/AF9 fusion types resulting from translocation t(9;11)(p22;q23) in acute myeloid leukemia
    • Scholl, C. et al. Development of a real-time RT-PCR assay for the quantification of the most frequent MLL/AF9 fusion types resulting from translocation t(9;11)(p22;q23) in acute myeloid leukemia. Genes Chromosomes Cancer 38, 274-280 (2003).
    • (2003) Genes Chromosomes Cancer , vol.38 , pp. 274-280
    • Scholl, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.