Optogenetic stimulation of the cochlear nucleus using channelrhodopsin-2 evokes activity in the central auditory pathways

Brain Research

Volumn 1599, Issue , 2015, Pages 44-56

  Darrow, Keith N ^a,b   Slama, Michaël C C ^b,c   Kozin, Elliott D ^b,c   Owoc, Maryanna ^a   Hancock, Kenneth ^c   Kempfle, Judith ^b,c   Edge, Albert ^b,c   Lacour, Stephanie ^d   Boyden, Edward ^e   Polley, Daniel ^b,c   Brown, M Christian ^b,c   Lee, Daniel J ^b,c  

^a WORCESTER STATE UNIVERSITY   (United States)

^b MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d EPFL   (Switzerland)

^e MIT MEDIA LAB   (United States)

Author keywords

Auditory cortex Synchronization index; ChR2; Inferior colliculus; Neural prosthesis

Indexed keywords

CHANNELRHODOPSIN 2; GLASS FIBER; GREEN FLUORESCENT PROTEIN; RHODOPSIN; UNCLASSIFIED DRUG; CHANNELRHODOPSIN 2, MOUSE;

ACOUSTIC NERVE FIBER; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUDITORY CORTEX; AUDITORY NERVOUS SYSTEM; AUDITORY STIMULATION; BLUE LIGHT; CELL BODY; CLICK; COCHLEAR NUCLEUS; CONTROLLED STUDY; EVOKED AUDITORY RESPONSE; EVOKED BRAIN STEM RESPONSE; GENE TRANSFER; INFERIOR COLLICULUS; MOUSE; NERVE FIBER; NEUROPROSTHESIS; NONHUMAN; OPTOGENETICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULSE RATE; TONOTOPY; WAVEFORM; ACTION POTENTIAL; ANIMAL; CBA MOUSE; CYTOLOGY; ELECTROSTIMULATION; EVOKED BRAIN STEM AUDITORY RESPONSE; FEASIBILITY STUDY; GENETICS; METABOLISM; NERVE CELL; PHOTOSTIMULATION; PHYSIOLOGY; PROCEDURES;

ACOUSTIC STIMULATION; ACTION POTENTIALS; ANIMALS; AUDITORY CORTEX; AUDITORY PATHWAYS; COCHLEAR NUCLEUS; ELECTRIC STIMULATION; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; FEASIBILITY STUDIES; GREEN FLUORESCENT PROTEINS; INFERIOR COLLICULI; MICE, INBRED CBA; NEURONS; OPTOGENETICS; PHOTIC STIMULATION; RHODOPSIN;

EID: 84923347483     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2014.11.044     Document Type: Article

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