-
1
-
-
0346279807
-
Evaluation of fluorescent compound interference in 4 fluorescence polarization assays: 2 kinases, 1 protease, and 1 phosphatase
-
Turek-Etienne, T. C.; Small, E. C.; Soh, S. C.; Xin, T. A.; Gaitonde, P. V.; Barrabee, E. B.; Hart, R. F.; Bryant, R. W. Evaluation of fluorescent compound interference in 4 fluorescence polarization assays: 2 kinases, 1 protease, and 1 phosphatase J. Biomol. Screening 2003, 8 (2) 176-184
-
(2003)
J. Biomol. Screening
, vol.8
, Issue.2
, pp. 176-184
-
-
Turek-Etienne, T.C.1
Small, E.C.2
Soh, S.C.3
Xin, T.A.4
Gaitonde, P.V.5
Barrabee, E.B.6
Hart, R.F.7
Bryant, R.W.8
-
3
-
-
84873748470
-
Fluorescence assay for protein post-translational tyrosine sulfation
-
Chen, B.-H.; Wang, C.-C.; Lu, L.-Y.; Hung, K.-S.; Yang, Y.-S. Fluorescence assay for protein post-translational tyrosine sulfation Anal. Bioanal. Chem. 2013, 405 (4) 1425-1429
-
(2013)
Anal. Bioanal. Chem.
, vol.405
, Issue.4
, pp. 1425-1429
-
-
Chen, B.-H.1
Wang, C.-C.2
Lu, L.-Y.3
Hung, K.-S.4
Yang, Y.-S.5
-
4
-
-
0033773937
-
Fluorescence polarization and anisotropy in high throughput screening: Perspectives and primer
-
Owicki, J. C. Fluorescence polarization and anisotropy in high throughput screening: perspectives and primer J. Biomol. Screening 2000, 5 (5) 297-306
-
(2000)
J. Biomol. Screening
, vol.5
, Issue.5
, pp. 297-306
-
-
Owicki, J.C.1
-
5
-
-
0030798464
-
Time-resolved fluorometry: An overview of the labels and core technologies for drug screening applications
-
Hemmila, I.; Webb, S. Time-resolved fluorometry: an overview of the labels and core technologies for drug screening applications Drug Discovery Today 1997, 2 (9) 373-381
-
(1997)
Drug Discovery Today
, vol.2
, Issue.9
, pp. 373-381
-
-
Hemmila, I.1
Webb, S.2
-
6
-
-
0033823060
-
The renaissance of fluorescence resonance energy transfer
-
Selvin, P. R. The renaissance of fluorescence resonance energy transfer Nat. Struct. Biol. 2000, 7 (9) 730-734
-
(2000)
Nat. Struct. Biol.
, vol.7
, Issue.9
, pp. 730-734
-
-
Selvin, P.R.1
-
7
-
-
78951472296
-
A fluorescence lifetime-based assay for Abelson kinase
-
Pritz, S.; Meder, G.; Doering, K.; Drueckes, P.; Woelcke, J.; Mayr, L. M.; Hassiepen, U. A fluorescence lifetime-based assay for Abelson kinase J. Biomol. Screening 2011, 16 (1) 65-72
-
(2011)
J. Biomol. Screening
, vol.16
, Issue.1
, pp. 65-72
-
-
Pritz, S.1
Meder, G.2
Doering, K.3
Drueckes, P.4
Woelcke, J.5
Mayr, L.M.6
Hassiepen, U.7
-
8
-
-
0031727047
-
Fluorescence correlation spectroscopy: Lead discovery by miniaturized HTS
-
Auer, M.; Moore, K. J.; Meyer-Almes, F. J.; Guenther, R.; Pope, A. J.; Stoeckli, K. A. Fluorescence correlation spectroscopy: lead discovery by miniaturized HTS Drug Discovery Today 1998, 3 (10) 457-465
-
(1998)
Drug Discovery Today
, vol.3
, Issue.10
, pp. 457-465
-
-
Auer, M.1
Moore, K.J.2
Meyer-Almes, F.J.3
Guenther, R.4
Pope, A.J.5
Stoeckli, K.A.6
-
9
-
-
0035111353
-
Single-molecule detection technologies in miniaturized high throughput screening: Binding assays for g protein-coupled receptors using fluorescence intensity distribution analysis and fluorescence anisotropy
-
Rudiger, M.; Haupts, U.; Moore, K. J.; Pope, A. J. Single-molecule detection technologies in miniaturized high throughput screening: binding assays for g protein-coupled receptors using fluorescence intensity distribution analysis and fluorescence anisotropy J. Biomol. Screening 2001, 6 (1) 29-37
-
(2001)
J. Biomol. Screening
, vol.6
, Issue.1
, pp. 29-37
-
-
Rudiger, M.1
Haupts, U.2
Moore, K.J.3
Pope, A.J.4
-
10
-
-
45949106612
-
The challenge of selecting protein kinase assays for lead discovery optimization
-
Ma, H.; Deacon, S.; Horiuchi, K. The challenge of selecting protein kinase assays for lead discovery optimization Expert Opin. Drug Discovery 2008, 3 (6) 607-621
-
(2008)
Expert Opin. Drug Discovery
, vol.3
, Issue.6
, pp. 607-621
-
-
Ma, H.1
Deacon, S.2
Horiuchi, K.3
-
11
-
-
77952545106
-
Apparent Activity in High-Throughput Screening: Origins of Compound-Dependent Assay Interference
-
Natasha, T.; Douglas, S. A.; James, I. Apparent Activity in High-Throughput Screening: Origins of Compound-Dependent Assay Interference Curr. Opin. Chem. Biol. 2010, 14 (3) 315-324
-
(2010)
Curr. Opin. Chem. Biol.
, vol.14
, Issue.3
, pp. 315-324
-
-
Natasha, T.1
Douglas, S.A.2
James, I.3
-
12
-
-
78650674952
-
False Positives in the Early Stages of Drug Discovery
-
Sink, R.; Gobec, S.; Pecar, S.; Zega, A. False Positives in the Early Stages of Drug Discovery Curr. Med. Chem. 2010, 17 (34) 4231-4255
-
(2010)
Curr. Med. Chem.
, vol.17
, Issue.34
, pp. 4231-4255
-
-
Sink, R.1
Gobec, S.2
Pecar, S.3
Zega, A.4
-
13
-
-
84904469522
-
A fluorescence lifetime-based binding assay for acetylpolyamine amidohydrolases from Pseudomonas aeruginosa using a [1,3]dioxolo[4,5-f][1,3]benzodioxole (DBD) ligand probe
-
Meyners, C.; Wawrzinek, R.; Kramer, A.; Hinz, S.; Wessig, P.; Meyer-Almes, F. J. A fluorescence lifetime-based binding assay for acetylpolyamine amidohydrolases from Pseudomonas aeruginosa using a [1,3]dioxolo[4,5-f][1,3]benzodioxole (DBD) ligand probe Anal. Bioanal. Chem. 2014, 406 (20) 4889-4897
-
(2014)
Anal. Bioanal. Chem.
, vol.406
, Issue.20
, pp. 4889-4897
-
-
Meyners, C.1
Wawrzinek, R.2
Kramer, A.3
Hinz, S.4
Wessig, P.5
Meyer-Almes, F.J.6
-
14
-
-
77950571108
-
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
-
Baell, J. B.; Holloway, G. A. New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays J. Med. Chem. 2010, 53 (7) 2719-2740
-
(2010)
J. Med. Chem.
, vol.53
, Issue.7
, pp. 2719-2740
-
-
Baell, J.B.1
Holloway, G.A.2
-
15
-
-
43049109870
-
Fluorescence Spectroscopic Profiling of Compound Libraries
-
Simeonov, A.; Jadhav, A.; Thomas, C. J.; Wang, Y.; Huang, R.; Southall, N. T.; Shinn, P.; Smith, J.; Austin, C. P.; Auld, D. S.; Inglese, J. Fluorescence Spectroscopic Profiling of Compound Libraries J. Med. Chem. 2008, 51 (8) 2363-2371
-
(2008)
J. Med. Chem.
, vol.51
, Issue.8
, pp. 2363-2371
-
-
Simeonov, A.1
Jadhav, A.2
Thomas, C.J.3
Wang, Y.4
Huang, R.5
Southall, N.T.6
Shinn, P.7
Smith, J.8
Austin, C.P.9
Auld, D.S.10
Inglese, J.11
-
16
-
-
84874277731
-
Native fluorescence detection of biomolecular and pharmaceutical compounds in capillary electrophoresis: Detector designs, performance and applications: A review
-
de Kort, B. J.; de Jong, G. J.; Somsen, G. W. Native fluorescence detection of biomolecular and pharmaceutical compounds in capillary electrophoresis: detector designs, performance and applications: a review Anal. Chim. Acta 2013, 766, 13-33
-
(2013)
Anal. Chim. Acta
, vol.766
, pp. 13-33
-
-
De Kort, B.J.1
De Jong, G.J.2
Somsen, G.W.3
-
17
-
-
77949353218
-
Characteristics of fluorescence emission
-
In; Wiley-VCH Verlag GmbH: Weinheim, Germany
-
Valeur, B., Characteristics of fluorescence emission. In Molecular Fluorescence: Principles and Applications; Wiley-VCH Verlag GmbH: Weinheim, Germany, 2002; pp 34-71.
-
(2002)
Molecular Fluorescence: Principles and Applications
, pp. 34-71
-
-
Valeur, B.1
-
18
-
-
0003475878
-
Introduction
-
In; Wiley-VCH Verlag GmbH
-
Valeur, B. Introduction. In Molecular Fluorescence; Wiley-VCH Verlag GmbH, 2001; pp 3-19.
-
(2001)
Molecular Fluorescence
, pp. 3-19
-
-
Valeur, B.1
-
21
-
-
84923354740
-
-
Southern Research Molecular Libraries Screening Center (SRMLSC)
-
Southern Research Molecular Libraries Screening Center (SRMLSC). PubChem Assays AID 709; 2007.
-
(2007)
PubChem Assays AID 709
-
-
-
22
-
-
67549135484
-
Theoretical prediction of the native fluorescence of pharmaceuticals
-
Albert-Garcia, J. R.; Anton-Fos, G. M.; Duart, M. J.; Lahuerta Zamora, L.; Martinez Calatayud, J. Theoretical prediction of the native fluorescence of pharmaceuticals Talanta 2009, 79 (2) 412-418
-
(2009)
Talanta
, vol.79
, Issue.2
, pp. 412-418
-
-
Albert-Garcia, J.R.1
Anton-Fos, G.M.2
Duart, M.J.3
Lahuerta Zamora, L.4
Martinez Calatayud, J.5
-
23
-
-
84876551083
-
Oversampling to Overcome Overfitting: Exploring the Relationship between Data Set Composition, Molecular Descriptors, and Predictive Modeling Methods
-
Chang, C.-Y.; Hsu, M.-T.; Esposito, E. X.; Tseng, Y. J. Oversampling to Overcome Overfitting: Exploring the Relationship between Data Set Composition, Molecular Descriptors, and Predictive Modeling Methods J. Chem. Inf. Model. 2013, 53 (4) 958-971
-
(2013)
J. Chem. Inf. Model.
, vol.53
, Issue.4
, pp. 958-971
-
-
Chang, C.-Y.1
Hsu, M.-T.2
Esposito, E.X.3
Tseng, Y.J.4
-
24
-
-
84923350251
-
-
C50: C5.0 Decision Trees and Rule-Based Models. (accessed March 4, 2014)
-
Kuhn, M.; Weston, S.; Coulter, N.; Quinlan, R. C50: C5.0 Decision Trees and Rule-Based Models. http://CRAN.R-project.org/package=C50 (accessed March 4, 2014).
-
-
-
Kuhn, M.1
Weston, S.2
Coulter, N.3
Quinlan, R.4
-
25
-
-
84869508839
-
Integrated in silico approaches for the prediction of Ames test mutagenicity
-
Modi, S.; Li, J.; Malcomber, S.; Moore, C.; Scott, A.; White, A.; Carmichael, P. Integrated in silico approaches for the prediction of Ames test mutagenicity J. Comput.-Aided Mol. Des. 2012, 26 (9) 1017-1033
-
(2012)
J. Comput.-Aided Mol. Des.
, vol.26
, Issue.9
, pp. 1017-1033
-
-
Modi, S.1
Li, J.2
Malcomber, S.3
Moore, C.4
Scott, A.5
White, A.6
Carmichael, P.7
-
27
-
-
0036434346
-
Two-photon fluorescence absorption and emission spectra of dyes relevant for cell imaging
-
Bestvater, F.; Spiess, E.; Stobrawa, G.; Hacker, M.; Feurer, T.; Porwol, T.; Berchner-Pfannschmidt, U.; Wotzlaw, C.; Acker, H. Two-photon fluorescence absorption and emission spectra of dyes relevant for cell imaging J. Microsc. 2002, 208 (2) 108-115
-
(2002)
J. Microsc.
, vol.208
, Issue.2
, pp. 108-115
-
-
Bestvater, F.1
Spiess, E.2
Stobrawa, G.3
Hacker, M.4
Feurer, T.5
Porwol, T.6
Berchner-Pfannschmidt, U.7
Wotzlaw, C.8
Acker, H.9
-
28
-
-
84055192230
-
Preparation and in Vivo Imaging of Lucifer Yellow Tagged Hydrogels
-
Moller, L.; Krause, A.; Bartsch, I.; Kirschning, A.; Witte, F.; Drager, G. Preparation and In Vivo Imaging of Lucifer Yellow Tagged Hydrogels Macromol. Symp. 2011, 309-310 (1) 222-228
-
(2011)
Macromol. Symp.
, vol.309-310
, Issue.1
, pp. 222-228
-
-
Moller, L.1
Krause, A.2
Bartsch, I.3
Kirschning, A.4
Witte, F.5
Drager, G.6
-
30
-
-
79959469908
-
A Comprehensive Support Vector Machine Binary hERG Classification Model Based on Extensive but Biased End Point hERG Data Sets
-
Shen, M.-Y.; Su, B.-H.; Esposito, E. X.; Hopfinger, A. J.; Tseng, Y. J. A Comprehensive Support Vector Machine Binary hERG Classification Model Based on Extensive but Biased End Point hERG Data Sets Chem. Res. Toxicol. 2011, 24 (6) 934-949
-
(2011)
Chem. Res. Toxicol.
, vol.24
, Issue.6
, pp. 934-949
-
-
Shen, M.-Y.1
Su, B.-H.2
Esposito, E.X.3
Hopfinger, A.J.4
Tseng, Y.J.5
-
31
-
-
84863304598
-
-
R Development Core Team. R Foundation for Statistical Computing: Vienna, Austria
-
R Development Core Team. R: A Language and Environment for Statistical Computing; R Foundation for Statistical Computing: Vienna, Austria, 2012.
-
(2012)
R: A Language and Environment for Statistical Computing
-
-
-
32
-
-
84923368932
-
-
Is See5/C5.0 Better Than C4.5? (accessed March 4, 2014)
-
Ross Quinlan, J. Is See5/C5.0 Better Than C4.5? http://rulequest.com/see5-comparison.html (accessed March 4, 2014).
-
-
-
Ross Quinlan, J.1
-
33
-
-
0342645323
-
Use of Structure-Activity Data to Compare Structure-Based Clustering Methods and Descriptors for Use in Compound Selection
-
Brown, R. D.; Martin, Y. C. Use of Structure-Activity Data To Compare Structure-Based Clustering Methods and Descriptors for Use in Compound Selection J. Chem. Inf. Comput. Sci. 1996, 36 (3) 572-584
-
(1996)
J. Chem. Inf. Comput. Sci.
, vol.36
, Issue.3
, pp. 572-584
-
-
Brown, R.D.1
Martin, Y.C.2
-
34
-
-
0033652279
-
On the selection of the training set in environmental QSAR analysis when compounds are clustered
-
Eriksson, L.; Johansson, E.; Muller, M.; Wold, S. On the selection of the training set in environmental QSAR analysis when compounds are clustered J. Chemom. 2000, 14 (5-6) 599-616
-
(2000)
J. Chemom.
, vol.14
, Issue.56
, pp. 599-616
-
-
Eriksson, L.1
Johansson, E.2
Muller, M.3
Wold, S.4
-
35
-
-
42149176773
-
Comparison of Similarity Coefficients for Clustering and Compound Selection
-
Haranczyk, M.; Holliday, J. Comparison of Similarity Coefficients for Clustering and Compound Selection J. Chem. Inf. Model. 2008, 48 (3) 498-508
-
(2008)
J. Chem. Inf. Model.
, vol.48
, Issue.3
, pp. 498-508
-
-
Haranczyk, M.1
Holliday, J.2
-
36
-
-
33645265985
-
Clustering methods and their uses in computational chemistry
-
Downs, G. M.; Barnard, J. M. Clustering methods and their uses in computational chemistry Rev. Comput. Chem. 2002, 18, 1-40
-
(2002)
Rev. Comput. Chem.
, vol.18
, pp. 1-40
-
-
Downs, G.M.1
Barnard, J.M.2
-
39
-
-
0015644825
-
A Fuzzy Relative of the ISODATA Process and Its Use in Detecting Compact Well-Separated Clusters
-
Dunn, J. C. A Fuzzy Relative of the ISODATA Process and Its Use in Detecting Compact Well-Separated Clusters J. Cybern. 1973, 3 (3) 32-57
-
(1973)
J. Cybern.
, vol.3
, Issue.3
, pp. 32-57
-
-
Dunn, J.C.1
-
40
-
-
2942746755
-
Clustering files of chemical structures using the fuzzy k-means clustering method
-
Holliday, J. D.; Rodgers, S. L.; Willett, P.; Chen, M. Y.; Mahfouf, M.; Lawson, K.; Mullier, G. Clustering files of chemical structures using the fuzzy k-means clustering method J. Chem. Inf. Comput. Sci. 2004, 44 (3) 894-902
-
(2004)
J. Chem. Inf. Comput. Sci.
, vol.44
, Issue.3
, pp. 894-902
-
-
Holliday, J.D.1
Rodgers, S.L.2
Willett, P.3
Chen, M.Y.4
Mahfouf, M.5
Lawson, K.6
Mullier, G.7
-
41
-
-
0035178111
-
Estimation of respiratory parameters via fuzzy clustering
-
Babuska, R.; Alic, L.; Louren, M. S.; Verbraak, A. F. M.; Bogaard, J. Estimation of respiratory parameters via fuzzy clustering Artif. Intell. Med. 2001, 21 (1-3) 91-105
-
(2001)
Artif. Intell. Med.
, vol.21
, Issue.13
, pp. 91-105
-
-
Babuska, R.1
Alic, L.2
Louren, M.S.3
Verbraak, A.F.M.4
Bogaard, J.5
-
42
-
-
0020110135
-
Fluorimetric determination of unsubstituted and 9(8)-O-acetylated sialic acids in erythrocyte membranes
-
Shukla, A. K.; Schauer, R. Fluorimetric determination of unsubstituted and 9(8)-O-acetylated sialic acids in erythrocyte membranes Hoppe-Seyler's Z. Physiol. Chem. 1982, 363 (3) 255-262
-
(1982)
Hoppe-Seyler's Z. Physiol. Chem.
, vol.363
, Issue.3
, pp. 255-262
-
-
Shukla, A.K.1
Schauer, R.2
-
43
-
-
84985080264
-
Absorption and Fluorescence Studies on Neutral and Cationic Isoalloxazines
-
Visser, A. J. W. G.; Miiller, F. Absorption and Fluorescence Studies on Neutral and Cationic Isoalloxazines Helv. Chim. Acta 1979, 62 (2) 593-608
-
(1979)
Helv. Chim. Acta
, vol.62
, Issue.2
, pp. 593-608
-
-
Visser, A.J.W.G.1
Miiller, F.2
|