Influence of substrate composition on human embryonic stem cell differentiation and extracellular matrix production in embryoid bodies

Biotechnology Progress

Volumn 31, Issue 1, 2015, Pages 212-219

  Laperle, Alex ^a   Masters, Kristyn S ^a   Palecek, Sean P ^a  

^a University of Wisconsin Madison   (United States)

Author keywords

Differentiation; Extracellular matrix; Human pluripotent stem cell

Indexed keywords

CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CELLS; CYTOLOGY; DIFFERENTIATION (CALCULUS); ENZYME ACTIVITY; MOBILE SECURITY; SUBSTRATES; TISSUE;

CELLULAR COMPONENTS; DEPOSITION PROFILES; DIFFERENTIATION PROCESS; EXTRACELLULAR MATRICES; EXTRACELLULAR MATRIX PRODUCTION; HUMAN EMBRYONIC STEM CELLS; PLURIPOTENT STEM CELLS; SUBSTRATE COMPOSITION;

STEM CELLS;

CULTURE MEDIUM; SCLEROPROTEIN;

CELL CULTURE TECHNIQUE; CELL DIFFERENTIATION; CELL LINE; CULTURE MEDIUM; CYTOLOGY; DRUG EFFECTS; EMBRYOID BODY; EMBRYONIC STEM CELL; HUMAN; METABOLISM;

CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL LINE; CULTURE MEDIA; EMBRYOID BODIES; EMBRYONIC STEM CELLS; EXTRACELLULAR MATRIX PROTEINS; HUMANS;

EID: 84923308081     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.2001     Document Type: Article

References (41)

1. Discher DE, Mooney DJ, Zandstra PW. Growth Factors, Matrices, and Forces Combine and Control Stem Cells. Science. 2009;324:1673-1677.
2. Lutolf MP, Gilbert PM, Blau HM. Designing materials to direct stem-cell fate. Nature. 2009;462:433-441.
3. Lutolf MP, Hubbell JA. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat Biotechnol. 2005;23:47-55.
4. Murry CE, Keller G. Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell. 2008;132:661-680.
5. Lutolf MP, Blau HM. Artificial stem cell niches. Adv Mater. 2009;21:3255-3268.
6. Bartlett RS, Thibeault SL, Prestwich GD. Therapeutic potential of gel-based injectables for vocal fold regeneration. Biomed Mater. 2012;7:024103.
7. Hoffman BD, Grashoff C, Schwartz MA. Dynamic molecular processes mediate cellular mechanotransduction. Nature. 2011;475:316-323.
8. Baharvand H, Azarnia M, Parivar K, Ashtiani SK. The effect of extracellular matrix on embryonic stem cell-derived cardiomyocytes. J Mol Cell Cardiol. 2005;38:495-503.
9. Taylor-Weiner H, Schwarzbauer JE, Engler AJ. Defined extracellular matrix components are necessary for definitive endoderm induction. Stem Cells. 2013;31:2084-2094.
10. Mei Y, Saha K, Bogatyrev SR, Yang J, Hook AL, Kalcioglu ZI, Cho SW, Mitalipova M, Pyzocha N, Rojas F, Van Vliet KJ, Davies MC, Alexander MR, Langer R, Jaenisch R, Anderson DG. Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells. Nat Mater. 2010;9:768-778.
11. Anderson DG, Levenberg S, Langer R. Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells. Nat Biotechnol. 2004;22:863-866.
12. Hunt GC, Singh P, Schwarzbauer JE. Endogenous production of fibronectin is required for self-renewal of cultured mouse embryonic stem cells. Exp Cell Res. 2012;318:1820-1831.
13. Azarin SM, Palecek SP. Matrix revolutions: a trinity of defined substrates for long-term expansion of human ESCs. Cell Stem Cell. 2010;7:7-8.
14. Rodin S, Domogatskaya A, Strom S, Hansson EM, Chien KR, Inzunza J, Hovatta O, Tryggvason K. Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511. Nat Biotechnol. 2010;28:611-615.
15. Braam SR, Zeinstra L, Litjens S, Ward-van Oostwaard D, van den Brink S, van Laake L, Lebrin F, Kats P, Hochstenbach R, Passier R, Sonnenberg A, Mummery CL. Recombinant vitronectin is a functionally defined substrate that supports human embryonic stem cell self-renewal via alphavbeta5 integrin. Stem Cells. 2008;26:2257-2265.
16. Evseenko D, Schenke-Layland K, Dravid G, Zhu Y, Hao QL, Scholes J, Wang XC, Maclellan WR, Crooks GM. Identification of the critical extracellular matrix proteins that promote human embryonic stem cell assembly. Stem Cells Dev. 2009;18:919-928.
17. Miyazaki T, Futaki S, Suemori H, Taniguchi Y, Yamada M, Kawasaki M, Hayashi M, Kumagai H, Nakatsuji N, Sekiguchi K, Kawase E. Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells. Nat Commun. 2012;3:1236.
18. Egles C, Claudepierre T, Manglapus MK, Champliaud M-F, Brunken WJ, Hunter DD. Laminins containing the β2 chain modulate the precise organization of CNS synapses. Mol Cell Neurosci. 2007;34:288-298.
19. Radner S, Banos C, Bachay G, Li YN, Hunter DD, Brunken WJ, Yee KT . β2 and γ3 laminins are critical cortical basement membrane components: ablation of Lamb2 and Lamc3 genes disrupts cortical lamination and produces dysplasia. Dev Neurobiol. 2013;73:209-229.
20. Beck K, Hunter I, Engel J. Structure and function of laminin: anatomy of a multidomain glycoprotein. Faseb J. 1990;4:148-160.
21. Cooper AR, MacQueen HA. Subunits of laminin are differentially synthesized in mouse eggs and early embryos. Dev Biol. 1983;96:467-471.
22. Miner JH, Yurchenco PD. Laminin functions in tissue morphogenesis. Annu Rev Cell Dev Biol. 2004;20:255-284.
23. Przybyla LM, Theunissen TW, Jaenisch R, Voldman J. Matrix Remodeling Maintains ESC Self-Renewal by Activating Stat3. Stem Cells. 2013;31:1097-1106.
24. Przybyla LM, Voldman J. Attenuation of extrinsic signaling reveals the importance of matrix remodeling on maintenance of embryonic stem cell self-renewal. Proc Natl Acad Sci U S A. 2012;109:835-840.
25. Page-McCaw A, Ewald AJ, Werb Z. Matrix metalloproteinases and the regulation of tissue remodelling. Nat Rev Mol Cell Biol. 2007;8:221-233.
26. Horejs C-M, Serio A, Purvis A, Gormley AJ, Bertazzo S, Poliniewicz A, Wang AJ, DiMaggio P, Hohenester E, Stevens MM . Biologically-active laminin-111 fragment that modulates the epithelial-to-mesenchymal transition in embryonic stem cells. Proc Natl Acad Sci U S A. 2014;111:5908-5913.
27. Itskovitz-Eldor J, Schuldiner M, Karsenti D, Eden A, Yanuka O, Amit M, Soreq H, Benvenisty N . Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers. Mol Med. 2000;6:88-95.
28. Vallier L, Pedersen R. Human embryonic stem cells. Stem Cell Rev. 2005;1:119-130.
29. Chen G, Gulbranson DR, Hou Z, Boulin JM, Ruotti V, Probasco MD, Smuga-Otto K, Howden SE, Diol NR, Propson NE, Wagner R, Lee GO, Antosiewicz-Bourget J, Teng JM, Thomson JA . Chemically defined conditions for human iPSC derivation and culture. Nat Methods. 2011;8:424-429.
30. Mohr JC, Zhang J, Azarin SM, Soerens AG, de Pablo JJ, Thomson JA, Lyons GE, Palecek SP, Kamp TJ . The microwell control of embryoid body size in order to regulate cardiac differentiation of human embryonic stem cells. Biomaterials. 2010;31:1885-1893.
31. Lippmann ES, Estevez-Silva MC, Ashton RS. Defined human pluripotent stem cell culture enables highly efficient neuroepithelium derivation without small molecule inhibitors. Stem Cells. 2014;32:1032-1042.
32. Schindelin J, Arganda-Carreras I, Frise E, Kaynig V, Longair M, Pietsch T, Preibisch S, Rueden C, Saalfeld S, Schmid B, Tinevez JY, White DJ, Hartenstein V, Eliceiri K, Tomancak P, Cardona A . Fiji: an open-source platform for biological-image analysis. Nat Methods. 2012;9:676-682.
33. Yang F, Cho SW, Son SM, Hudson SP, Bogatyrev S, Keung L, Kohane DS, Langer R, Anderson Dg . Combinatorial extracellular matrices for human embryonic stem cell differentiation in 3D. Biomacromolecules. 2010;11:1909-1914.
34. Selekman JA, Das A, Grundl NJ, Palecek SP. Improving efficiency of human pluripotent stem cell differentiation platforms using an integrated experimental and computational approach. Biotechnol Bioeng. 2013;110:3024-3037.
35. Raghavan S, Bitar KN. The influence of extracellular matrix composition on the differentiation of neuronal subtypes in tissue engineered innervated intestinal smooth muscle sheets. Biomaterials. 2014;35:7429-7440.
36. Li Y, Liu M, Yan Y, Yang ST. Neural differentiation from pluripotent stem cells: the role of natural and synthetic extracellular matrix. World J Stem Cells. 2014;6:11-23.
37. Mammadov B, Guler MO, Tekinay AB. Extracellular matrix mimetic peptide scaffolds for neural stem cell culture and differentiation. Methods Mol Biol. 2014;1202:131-148.
38. Cen L, Liu W, Cui L, Zhang W, Cao Y. Collagen tissue engineering: development of novel biomaterials and applications. Pediatr Res. 2008;63:492-496.
39. Seppinen L, Pihlajaniemi T. The multiple functions of collagen XVIII in development and disease. Matrix Biol. 2011;30:83-92.
40. Li S, Harrison D, Carbonetto S, Fassler R, Smyth N, Edgar D, Yurchenco PD . Matrix assembly, regulation, and survival functions of laminin and its receptors in embryonic stem cell differentiation. J Cell Biol. 2002;157:1279-1290.
41. Hynes RO, Naba A. Overview of the matrisome-an inventory of extracellular matrix constituents and functions. Cold Spring Harb Perspect Biol. 2012;4:a004903.