In vivo application of chitosan to improve bioavailability of cyanocobalamin, a form of vitamin B12, following intraintestinal administration in rats

International Journal of Pharmaceutics

Volumn 483, Issue 1-2, 2015, Pages 250-255

  Goto, Yuko ^a   Masuda, Ayumi ^a   Aiba, Tetsuya ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Anemia; Bioavailability; Chitosan; Cyanocobalamin; Gastrectomy; Vitamin B12

Indexed keywords

CHITOSAN; CYANOCOBALAMIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DEACETYLATION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; IN VIVO STUDY; INTESTINE ABSORPTION; MALE; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; VITAMIN BLOOD LEVEL; VOLUME OF DISTRIBUTION AT STEADY-STATE; ANIMAL; BIOAVAILABILITY; BLOOD; CHEMISTRY; INTRAVENOUS DRUG ADMINISTRATION; TIME; WISTAR RAT;

ADMINISTRATION, INTRAVENOUS; ANIMALS; BIOLOGICAL AVAILABILITY; CHITOSAN; INTESTINAL ABSORPTION; MALE; RATS; RATS, WISTAR; TIME FACTORS; VITAMIN B 12;

EID: 84923287575     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.02.016     Document Type: Article

References (25)

1. L.H. Allen How common is vitamin B-12 deficiency? Am. J. Clin. Nutr. 89 2009 693S 696S
2. B.J. Aungst Absorption enhancers: applications and advances AAPS J. 14 2012 10 18
3. 12) deficiency Blood 112 2008 2214 2221
4. R.H. Chen, and M.L. Tsaih Effect of temperature on intrinsic viscosity and conformation of chitosans in dilute HCl solution Int. J. Biol. Macromol. 23 1998 135 141
5. S.W. Choi, S. Friso, H. Ghandour, P.J. Bagley, J. Selhub, and J.B. Mason Vitamin B-12 deficiency induces anomalies of base substitution and methylation in the DNA of rat colonic epithelium J. Nutr. 134 2004 750 755
6. V. Gupta, B.H. Hwang, N. Doshi, and S. Mitragotri A permeation enhancer for increasing transport of therapeutic macromolecules across the intestine J. Control. Release 172 2013 541 549
7. C.H. Hagedorn, and D.H. Alpers Distribution of intrinsic factor-vitamin B12 receptors in human intestine Gastroenterology 73 1977 1019 1022
8. S. Kalra, R. Ahuja, E. Mutti, D. Veber, S. Seetharam, G. Scalabrino, and B. Seetharam Cobalamin-mediated regulation of transcobalamin receptor levels in rat organs Arch. Biochem. Biophys. 463 2007 128 132
9. K. Kaushansky, and T.J. Kipps Hematopoietic agents: growth factors, minerals, and vitamins L.L. Brunton, B.A. Chabner, B.C. Knollmann, The Pharmacological Basis of Therapeutics, 12/e 2011 McGraw-Hill Press New York 1067 1099
10. I.M. van der Lubben, J.C. Verhoef, G. Borchard, and H.E. Junginger Chitosan and its derivatives in mucosal drug and vaccine delivery Eur. J. Pharm. Sci. 14 2001 201 207
11. H.L. Luessen, B.J. de Leeuw, M.W. Langemeÿer, A.B. de Boer, J.C. Verhoef, and H.E. Junginger Mucoadhesive polymers in peroral peptide drug delivery. VI. Carbomer and chitosan improve the intestinal absorption of the peptide drug buserelin in vivo Pharm. Res. 13 1996 1668 1672
12. A. Masuda, Y. Goto, Y. Kurosaki, and T. Aiba In vivo application of chitosan to facilitate intestinal acyclovir absorption in rats J. Pharm. Sci. 101 2012 2449 2456
13. A. Merzlikine, C. Rotter, B. Rago, J. Poe, C. Christoffersen, V.H. Thomas, M. Troutman, and A. El-Kattan Effect of chitosan glutamate carbomer 974P, and EDTA on the in vitro Caco-2 permeability and oral pharmacokinetic profile of acyclovir in rats Drug Dev. Ind. Pharm. 35 2009 1082 1091
14. J.H. Park, G. Saravanakumar, K. Kim, and I.C. Kwon Targeted delivery of low molecular drugs using chitosan and its derivatives Adv. Drug Deliv. Rev. 62 2010 28 41
15. E.V. Quadros Advances in the understanding of cobalamin assimilation and metabolism Br. J. Haematol. 148 2010 195 204
16. G. Ranaidi, I. Marigliano, I. Vespignani, G. Perozzi, and Y. Sambuy The effect of chitosan and other polycations on tight junction permeability in the human intestinal Caco-2 cell line J. Nutr. Biochem. 13 2002 157 167
17. M. Rowland, and T.N. Tozer Estimation of absorption kinetics from plasma concentration data M. Rowland, T.N. Tozer, Clinical Pharmacokinetics, 3/e 1994 Lippincott Williams & Wilkins Philadelphia 478 484
18. G. Scalabrino, F.R. Buccellato, G. Tredici, A. Morabito, E.C. Lorenzini, R.H. Allen, and J. Lindenbaum Enhanced levels of biochemical markers for cobalamin deficiency in totally gastrectomized rats: uncoupling of the enhancement from the severity of spongy vacuolation in spinal cord Exp. Neurol. 144 1997 258 265
19. N.G. Schipper, S. Olsson, J.A. Hoogstraate, A.G. deBoer, K.M. Vårum, and P. Artursson Chitosans as absorption enhancers for poorly absorbable drugs 2: mechanism of absorption enhancement Pharm. Res. 14 1997 923 929
20. B. Seetharam, J.E. Bakke, and D.H. Alpers Binding of intrinsic factor to ileal brush border membrane in the rat Biochem. Biophys. Res. Commun. 115 1983 238 244
21. P. Shah, V. Jogani, P. Mishra, A.K. Mishra, T. Bagchi, and A. Misra Modulation of ganciclovir intestinal absorption in presence of absorption enhancers J. Pharm. Sci. 96 2007 2710 2722
22. J. Smith, E. Wood, and M. Dornish Effect of chitosan on epithelial cell tight junctions Pharm. Res. 21 2004 43 49
23. C. Takayama, F. Mukaizawa, T. Fujita, K. Ogawara, K. Higaki, and T. Kimura Amino acids suppress apoptosis induced by sodium laurate, an absorption enhancer J. Pharm. Sci. 98 2009 4629 4638
24. A. Yamamoto, T. Okagawa, A. Kotani, T. Uchiyama, T. Shimura, S. Tabata, S. Kondo, and S. Muranishi Effects of different absorption enhancers on the permeation of ebiratide, an ACTH analogue, across intestinal membranes J. Pharm. Pharmacol. 49 1997 1057 1061
25. H. Yu, Y.Q. Hu, F.C. Ip, Z. Zuo, Y.F. Han, and N.Y. Ip Intestinal transport of bis(12)-hupyridone in Caco-2 cells and its improved permeability by the surfactant Brij-35 Biopharm. Drug Dispos. 32 2011 140 150