Mediodorsal thalamus hypofunction impairs flexible goal-directed behavior

Biological Psychiatry

Volumn 77, Issue 5, 2015, Pages 445-453

  Parnaudeau, Sébastien ^a   Taylor, Kathleen ^a   Bolkan, Scott S ^a   Ward, Ryan D ^a   Balsam, Peter D ^a   Kellendonk, Christoph ^a  

^a Howard Hughes Medical Institute   (United States)

Author keywords

Behavioral flexibility; DREADD system; Goal directed behavior; Mediodorsal thalamus; Pavlovian to instrumental transfer; Schizophrenia

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COGNITION; COGNITIVE DEFECT; HISTOLOGY; LEARNING; LEARNING TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; THALAMUS DORSOMEDIAL NUCLEUS; ANIMAL; ASSOCIATION; C57BL MOUSE; CONDITIONED REFLEX; INSTRUMENTAL CONDITIONING; MALE; MOTIVATION; PATHOPHYSIOLOGY; PERCEPTIVE DISCRIMINATION; PHYSIOLOGY; REINFORCEMENT; REWARD; THALAMUS;

ANIMALS; CONDITIONING, CLASSICAL; CONDITIONING, OPERANT; CUES; DISCRIMINATION (PSYCHOLOGY); EXTINCTION, PSYCHOLOGICAL; GOALS; MALE; MICE, INBRED C57BL; REVERSAL LEARNING; REWARD; THALAMUS; TRANSFER (PSYCHOLOGY);

EID: 84923257024     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2014.03.020     Document Type: Article

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