Prenatal organochlorine and methylmercury exposure and memory and learning in school-age children in communities near the new bedford harbor superfund site, Massachusetts

Environmental Health Perspectives

Volumn 122, Issue 11, 2014, Pages 1253-1259

  Orenstein, Sara T C ^a,b   Thurston, Sally W ^c   Bellinger, David C ^a,b   Schwartz, Joel D ^a,b   Amarasiriwardena, Chitra J ^b   Altshul, Larisa M ^a,d   Korrick, Susan A ^a,b  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^d Environmental Health & Engineering Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZENE DERIVATIVE; DICHLORODIPHENYLDICHLOROETHYLENE; METHYLMERCURY; ORGANOCHLORINE DERIVATIVE; POLYCHLORINATED BIPHENYL; UNCLASSIFIED DRUG; 1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; CHLORINATED HYDROCARBON; MERCURY; METHYLMERCURY DERIVATIVE; PESTICIDE; POLLUTANT;

ADULT; ARTICLE; BECK DEPRESSION INVENTORY; BREAST FEEDING; CHEMICAL ANALYSIS; CHILD; EDUCATION; ELECTRON CAPTURE DETECTION; FEMALE; GAS CHROMATOGRAPHY; HUMAN; INTELLIGENCE QUOTIENT; INTERVIEW; LEARNING; LEARNING INDEX; LIMIT OF DETECTION; MALE; MEMORY; NEUROTOXICITY; PRENATAL EXPOSURE; PRIORITY JOURNAL; PSYCHOLOGIC ASSESSMENT; QUESTIONNAIRE; SCHOOL CHILD; SMOKING; STATISTICAL ANALYSIS; VERBAL MEMORY; VISUAL MEMORY; VISUAL MEMORY INDEX; WIDE RANGE ASSESSMENT OF MEMORY AND LEARNING; ADVERSE EFFECTS; BLOOD; CHEMISTRY; DRUG EFFECTS; ENVIRONMENTAL EXPOSURE; EPIDEMIOLOGY; HAIR; METABOLISM; MULTIVARIATE ANALYSIS; POLLUTANT; PREGNANCY; STATISTICS AND NUMERICAL DATA; TOXICITY; UNITED STATES;

CHILD; DICHLORODIPHENYL DICHLOROETHYLENE; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; FEMALE; HAIR; HUMANS; HYDROCARBONS, CHLORINATED; LEARNING; MALE; MASSACHUSETTS; MATERNAL EXPOSURE; MEMORY; MERCURY; METHYLMERCURY COMPOUNDS; MULTIVARIATE ANALYSIS; PESTICIDES; POLYCHLORINATED BIPHENYLS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS;

EID: 84923242379     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1307804     Document Type: Article

References (56)

1. Amin-Zaki L, Elhassani S, Majeed MA, Clarkson TW, Doherty RA, Greenwood M. 1974. Intra-uterine methylmercury poisoning in Iraq. Pediatrics 54(5):587-595.
2. Beck A, Steer R, Brown G. 1996. Beck Depression Inventory-II. San Antonio, TX:Psychological Corporation.
3. Budtz-Jorgensen E, Grandjean P, Jorgensen PJ, Weihe P, Keiding N. 2004. Association between mercury concentrations in blood and hair in methylmercury-exposed subjects at different ages. Environ Res 95(3):385-393.
4. Burbacher TM, Grant KS, Mayfield DB, Gilbert SG, Rice DC. 2005. Prenatal methylmercury exposure affects spatial vision in adult monkeys. Toxicol Appl Pharmacol 208(1):21-28.
5. Caldwell BM, Bradley RH. 1985. Home Observation for Measurement of the Enviroment. New York:Dorsey.
6. Castoldi AF, Onishchenko N, Johansson C, Coccini T, Roda E, Vahter M, et al. 2008. Neurodevelopmental toxicity of methylmercury: laboratory animal data and their contribution to human risk assessment. Regul Toxicol Pharmacol 51(2):215-229.
7. Choi AL, Levy JI, Dockery DW, Ryan LM, Tolbert PE, Altshul L., et al. 2006. Does living near a Superfund site contribute to higher polychlorinated biphenyl (PCB) exposure? Environ Health Perspect 114:1092-1098; doi:10.1289/ehp.8827.
8. Cordier S, Garel M, Mandereau L, Morcel H, Doineau P, Gosme- Seguret S, et al. 2002. Neurodevelopmental investigations among methylmercury-exposed children in French Guiana. Environ Res 89(1):1-11.
9. Darvill T, Lonky E, Reihman J, Stewart P, Pagano J. 2000. Prenatal exposure to PCBs and infant performance on the Fagan Test of Infant Intelligence. Neurotoxicology 21(6):1029-1038.
10. Dasari S, Yuan Y. 2009. Low level postnatal methylmercury exposure in vivo alters developmental forms of short-term synaptic plasticity in the visual cortex of rat. Toxicol Appl Pharmacol 240(3):412-422.
11. Davidson PW, Kost J, Myers GJ, Cox C, Clarkson TW, Shamlaye CF. 2001. Methylmercury and neurodevelopment: reanalysis of the Seychelles Child Development Study outcomes at 66 months of age [Letter]. JAMA 285(10):1291-1293.
12. Davidson PW, Myers GJ, Cox C, Wilding GE, Shamlaye CF, Huang LS, et al. 2006. Methylmercury and neurodevelopment: longitudinal analysis of the Seychelles child development cohort. Neurotoxicol Teratol 28(5):529-535.
13. Davidson PW, Strain JJ, Myers GJ, Thurston SW, Bonham MP, Shamlaye CF, et al. 2008. Neurodevelopmental effects of maternal nutritional status and exposure to methylmercury from eating fish during pregnancy. Neurotoxicology 29(5):767-775.
14. Denkins YM, Woods J, Whitty JE, Hannigan JH, Martier SS, Sokol RJ, et al. 2000. Effects of gestational alcohol exposure on the fatty acid composition of umbilical cord serum in humans. Am J Clin Nutr 71(1 suppl):300S-306S.
15. Eskenazi B, Marks AR, Bradman A, Fenster L, Johnson C, Barr DB, et al. 2006. In utero exposure to dichlorodiphenyltrichloroethane (DDT) and dichlorodiphenyldichloroethylene (DDE) and neurodevelopment among young Mexican American children. Pediatrics 118(1):233-241.
16. Ethier AA, Muckle G, Bastien C, Dewailly E, Ayotte P, Arfken C, et al. 2012. Effects of environmental contaminant exposure on visual brain development: a prospective electrophysiological study in school-aged children. Neurotoxicology 33(5):1075-1085.
17. Gladen BC, Rogan WJ. 1991. Effects of perinatal polychlorinated biphenyls and dichlorodiphenyl dichloroethene on later development. J Pediatr 119(1):58-63.
18. Grandjean P, Budtz-Jorgensen E, White RF, Jorgensen PJ, Weihe P, Debes F, et al. 1999a. Methylmercury exposure biomarkers as indicators of neurotoxicity in children aged 7 years. Am J Epidemiol 150(3):301-305.
19. Grandjean P, Weihe P, Burse VW, Needham LL, Storr-Hansen E, Heinzow B, et al. 2001. Neurobehavioral deficits associated with PCB in 7-year-old children prenatally exposed to seafood neurotoxicants. Neurotoxicol Teratol 23(4):305-317.
20. Grandjean P, Weihe P, White RF, Debes F, Araki S, Yokoyama K, et al. 1997. Cognitive deficit in 7-year-old children with prenatal exposure to methylmercury. Neurotoxicol Teratol 19(6):417-428.
21. Grandjean P, White RF, Nielsen A, Cleary D, de Oliveira Santos EC. 1999b. Methylmercury neurotoxicity in Amazonian children downstream from gold mining. Environ Health Perspect 107:587-591.
22. Harada M. 1978. Congenital Minamata disease: intrauterine methylmercury poisoning. Teratology 18(2):285-288.
23. Herrick RF, McClean MD, Meeker JD, Baxter LK, Weymouth GA. 2004. An unrecognized source of PCB contamination in schools and other buildings. Environ Health Perspect 112:1051-1053; doi:10.1289/ehp.6912.
24. Hobel CJ, Hyvarinen MA, Okada DM, Oh W. 1973. Prenatal and intrapartum high-risk screening. I. Prediction of the highrisk neonate. Am J Obstet Gynecol 117(1):1-9.
25. Jacobson JL, Jacobson SW. 1996. Intellectual impairment in children exposed to polychlorinated biphenyls in utero. N Engl J Med 335(11):783-789.
26. Jacobson JL, Jacobson SW, Humphrey HE. 1990. Effects of in utero exposure to polychlorinated biphenyls and related contaminants on cognitive functioning in young children. J Pediatr 116(1):38-45.
27. Jacobson JL, Jacobson SW, Padgett RW, Brumitt GA, Billings RL. 1992. Effects of prenatal PCB exposure on cognitive processing efficiency and sustained attention. Dev Psychol 28(2):297.
28. Kaufman A, Kaufman N. 1990. Kaufman Brief Intelligence Test. Circle Pines, MN:American Guidance Service.
29. Kershaw TG, Clarkson TW, Dhahir PH. 1980. The relationship between blood levels and dose of methylmercury in man. Arch Environ Health 35(1):28-36.
30. Kim R, Aro A, Rotnitzky A, Amarasiriwardena C, Hu H. 1995. K X-ray fluorescence measurements of bone lead concentration: the analysis of low-level data. Phys Med Biol 40(9):1475-1485.
31. Korrick SA, Altshul L. 1998. High breast milk levels of polychlorinated biphenyls (PCBs) among four women living adjacent to a PCB-contaminated waste site. Environ Health Perspect 106:513-518.
32. Korrick SA, Altshul L., Tolbert PE, Burse VW, Needham LL, Monson RR. 2000. Measurement of PCBs, DDE, and hexachlorobenzene in cord blood from infants born in towns adjacent to a PCB-contaminated waste site. J Expo Anal Environ Epidemiol 10(6):743-754.
33. Lai TJ, Guo YL, Guo NW, Hsu CC. 2001. Effect of prenatal exposure to polychlorinated biphenyls on cognitive development in children: a longitudinal study in Taiwan. Br J Psychiatry Suppl 40:s49-s52.
34. Lam HS, Kwok KM, Chan PH, So HK, Li AM, Ng PC, et al. 2013. Long term neurocognitive impact of low dose prenatal methylmercury exposure in Hong Kong. Environ Int 54:59-64.
35. Longnecker MP, Wolff MS, Gladen BC, Brock JW, Grandjean P, Jacobson JL, et al. 2003. Comparison of polychlorinated biphenyl levels across studies of human neurodevelopment. Environ Health Perspect 111:65-70;doi:10.1289/ehp.5463.
36. Myers GJ, Davidson PW. 1998. Prenatal methylmercury exposure and children: neurologic, developmental, and behavioral research. Environ Health Perspect 106(suppl 3):841-847.
37. Myers GJ, Davidson PW, Cox C, Shamlaye CF, Palumbo D, Cernichiari E, et al. 2003. Prenatal methylmercury exposure from ocean fish consumption in the Seychelles child development study. Lancet 361(9370):1686-1692.
38. Ohba T, Kurokawa N, Nakai K, Shimada M, Suzuki K, Sugawara N, et al. 2008. Permanent waving does not change mercury concentration in the proximal segment of hair close to scalp. Tohoku J Exp Med 214(1):69-78.
39. Oken E, Radesky JS, Wright RO, Bellinger DC, Amarasiriwardena CJ, Kleinman KP, et al. 2008. Maternal fish intake during pregnancy, blood mercury levels, and child cognition at age 3 years in a US cohort. Am J Epidemiol 167(10):1171-1181.
40. Oken E, Wright RO, Kleinman KP, Bellinger D, Amarasiriwardena CJ, Hu H, et al. 2005. Maternal fish consumption, hair mercury, and infant cognition in a U.S. cohort. Environ Health Perspect 113:1376-1380; doi:10.1289/ehp.8041.
41. Palumbo DR, Cox C, Davidson PW, Myers GJ, Choi A, Shamlaye C, et al. 2000. Association between prenatal exposure to methylmercury and cognitive functioning in Seychellois children: a reanalysis of the McCarthy Scales of Children’s Ability from the main cohort study. Environ Res 84(2):81-88.
42. Sagiv SK, Thurston SW, Bellinger DC, Altshul L., Korrick SA. 2012a. Neuropsychological measures of attention and impulse control among 8-year-old children exposed prenatally to organochlorines. Environ Health Perspect 120:904-909; doi:10.1289/ehp.1104372.
43. Sagiv SK, Thurston SW, Bellinger DC, Amarasiriwardena C, Korrick SA. 2012b. Prenatal exposure to mercury and fish consumption during pregnancy and attention-deficit/ hyperactivity disorder-related behavior in children. Arch Pediatr Adolesc Med 166(12):1123-1131.
44. Sagiv SK, Thurston SW, Bellinger DC, Tolbert PE, Altshul L., Korrick SA. 2010. Prenatal organochlorine exposure and behaviors associated with attention deficit hyperactivity disorder in school-aged children. Am J Epidemiol 171(5):593-601.
45. Saint-Amour D, Roy MS, Bastien C, Ayotte P, Dewailly E, Despres C, et al. 2006. Alterations of visual evoked potentials in preschool Inuit children exposed to methylmercury and polychlorinated biphenyls from a marine diet. Neurotoxicology 27(4):567-578.
46. Salvini S, Hunter DJ, Sampson L, Stampfer MJ, Colditz GA, Rosner B, et al. 1989. Food-based validation of a dietary questionnaire: the effects of week-to-week variation in food consumption. Int J Epidemiol 18(4):858-867.
47. Sheslow D, Adams W. 1990. WRAML: Wide Range Assessment of Memory and Learning: Administration Manual. Wilmington, DE:Wide Range Inc.
48. Sokol RJ, Rosen MG, Stojkov J, Chik L. 1977. Clinical application of high-risk scoring on an obstetric service. Am J Obstet Gynecol 128(6):652-661.
49. Stewart P, Darvill T, Lonky E, Reihman J, Pagano J, Bush B. 1999. Assessment of prenatal exposure to PCBs from maternal consumption of Great Lakes fish: an analysis of PCB pattern and concentration. Environ Res 80(2):S87-S96.
50. Stewart PW, Reihman J, Lonky EI, Darvill TJ, Pagano J. 2003. Cognitive development in preschool children prenatally exposed to PCBs and MeHg. Neurotoxicol Teratol 25(1):11-22.
51. Suzuki T. 1988. Hair and nails: advantages and pitfalls when used in biological monitoring. In: Biological Monitoring of Toxic Metals (Clarkson TW, Friberg L, Nordberg GF, Sager PR, eds). New York:Plenum, 623-640.
52. Torres-Sanchez L, Schnaas L, Rothenberg SJ, Cebrian ME, Osorio-Valencia E, del Carmen Hernandez M, et al. 2013. Prenatal p,p‑DDE exposure and neurodevelopment among children 3.5-5 years of age. Environ Health Perspect 121:263-268; doi:10.1289/ehp.1205034.
53. Van den Berg M, Birnbaum LS, Denison M, De Vito M, Farland W, Feeley M, et al. 2006. The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol Sci 93(2):223-241.
54. Vreugdenhil HJ, Mulder PG, Emmen HH, Weisglas-Kuperus N. 2004. Effects of perinatal exposure to PCBs on neuropsychological functions in the Rotterdam cohort at 9 years of age. Neuropsychology 18(1):185-193.
55. White RF, Palumbo CL, Yurgelun-Todd DA, Heaton KJ, Weihe P, Debes F, et al. 2011. Functional MRI approach to developmental methylmercury and polychlorinated biphenyl neurotoxicity. Neurotoxicology 32(6):975-980.
56. World Health Organization. 1990. IPCS Environmental Health Criteria 101 Methylmercury. Geneva:World Health Organization.