The solution structure of the MANEC-type domain from hepatocyte growth factor activator inhibitor-1 reveals an unexpected PAN/apple domain-type fold

Biochemical Journal

Volumn 466, Issue , 2015, Pages 299-309

  Hong, Zebin ^a   Nowakowski, Michal ^b   Spronk, Chris ^c   Petersen, Steen V ^a   Andreasen, Peter A ^a   Koźmiński, Wiktor ^b   Mulder, Frans A A ^a   Jensen, Jan K ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF WARSAW   (Poland)

^c Spronk NMR ^*  (Lithuania)

Author keywords

NMR; Serine protease inhibitor; Structure homology

Indexed keywords

HEPATOCYTE GROWTH FACTOR ACTIVATOR INHIBITOR 1; SCATTER FACTOR; UNCLASSIFIED DRUG; ISOPROTEIN; LEUKOCYTE ELASTASE INHIBITOR; MUTANT PROTEIN; RECOMBINANT PROTEIN; SIGNAL PEPTIDE; SPINT1 PROTEIN, HUMAN;

ALPHA HELIX; ARTICLE; DISULFIDE BOND; N TERMINUS WITH EIGHT CYSTEINE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CHEMICAL STRUCTURE; CHEMISTRY; CLASSIFICATION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; PROTEIN MOTIF; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; SMALL ANGLE SCATTERING; SOLUBILITY; X RAY DIFFRACTION;

MUS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN ISOFORMS; PROTEIN SORTING SIGNALS; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; PROTEINASE INHIBITORY PROTEINS, SECRETORY; RECOMBINANT PROTEINS; SCATTERING, SMALL ANGLE; SOLUBILITY; X-RAY DIFFRACTION;

EID: 84923238756     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20141236     Document Type: Article

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