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Volumn 13, Issue 2, 2015, Pages 974-983

Trabectedin in soft tissue sarcomas

Author keywords

Chemotherapy; DNA minor groove binder; ET 743; Soft tissue sarcoma; Trabectedin

Indexed keywords

CISPLATIN; DOXORUBICIN; GEMCITABINE; GRANULOCYTE COLONY STIMULATING FACTOR; IFOSFAMIDE; TRABECTEDIN; 1,3 DIOXOLANE DERIVATIVE; ALKYLATING AGENT; TETRAHYDROISOQUINOLINE DERIVATIVE;

EID: 84923227158     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md13020974     Document Type: Review
Times cited : (19)

References (46)
  • 2
    • 61549104994 scopus 로고    scopus 로고
    • Development of yondelis[registered sign] (trabectedin, et-743). A semisynthetic process solves the supply problem
    • Cuevas, C.; Francesch, A. Development of yondelis[registered sign] (trabectedin, et-743). A semisynthetic process solves the supply problem. Nat. Prod. Rep. 2009, 26, 322-337.
    • (2009) Nat. Prod. Rep. , vol.26 , pp. 322-337
    • Cuevas, C.1    Francesch, A.2
  • 3
    • 77955505177 scopus 로고    scopus 로고
    • A review of trabectedin (et-743): A unique mechanism of action
    • D'Incalci, M.; Galmarini, C.M. A review of trabectedin (et-743): A unique mechanism of action. Mol. Cancer Ther. 2010, 9, 2157-2163.
    • (2010) Mol. Cancer Ther. , vol.9 , pp. 2157-2163
    • D'Incalci, M.1    Galmarini, C.M.2
  • 4
    • 55549128608 scopus 로고    scopus 로고
    • Transcription-coupled DNA double-strand breaks are mediated via the nucleotide excision repair and the mre11-rad50-nbs1 complex
    • Guirouilh-Barbat, J.; Redon, C.; Pommier, Y. Transcription-coupled DNA double-strand breaks are mediated via the nucleotide excision repair and the mre11-rad50-nbs1 complex. Mol. Biol. Cell 2008, 19, 3969-3981.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 3969-3981
    • Guirouilh-Barbat, J.1    Redon, C.2    Pommier, Y.3
  • 8
    • 20144388299 scopus 로고    scopus 로고
    • Anti-inflammatory properties of the novel antitumor agent yondelis (trabectedin): Inhibition of macrophage differentiation and cytokine production
    • Allavena, P.; Signorelli, M.; Chieppa, M.; Erba, E.; Bianchi, G.; Marchesi, F.; Olimpio, C.O.; Bonardi, C.; Garbi, A.; Lissoni, A.; et al. Anti-inflammatory properties of the novel antitumor agent yondelis (trabectedin): Inhibition of macrophage differentiation and cytokine production. Cancer Res. 2005, 65, 2964-2971.
    • (2005) Cancer Res. , vol.65 , pp. 2964-2971
    • Allavena, P.1    Signorelli, M.2    Chieppa, M.3    Erba, E.4    Bianchi, G.5    Marchesi, F.6    Olimpio, C.O.7    Bonardi, C.8    Garbi, A.9    Lissoni, A.10
  • 10
    • 84896722431 scopus 로고    scopus 로고
    • Trabectedin and plitidepsin: Drugs from the sea that strike the tumor microenvironment
    • Galmarini, C.M.; Incalci, M.; Allavena, P. Trabectedin and plitidepsin: Drugs from the sea that strike the tumor microenvironment. Mar. Drugs 2014, 12, 719-733.
    • (2014) Mar. Drugs , vol.12 , pp. 719-733
    • Galmarini, C.M.1    Incalci, M.2    Allavena, P.3
  • 11
    • 84906092874 scopus 로고    scopus 로고
    • Trabectedin, a drug acting on both cancer cells and the tumour microenvironment
    • D'Incalci, M.; Badri, N.; Galmarini, C.M.; Allavena, P. Trabectedin, a drug acting on both cancer cells and the tumour microenvironment. Br. J. Cancer 2014, 111, 646-650.
    • (2014) Br. J. Cancer , vol.111 , pp. 646-650
    • D'Incalci, M.1    Badri, N.2    Galmarini, C.M.3    Allavena, P.4
  • 18
    • 84859856689 scopus 로고    scopus 로고
    • A systems biology approach to characterize the regulatory networks leading to trabectedin resistance in an in vitro model of myxoid liposarcoma
    • Uboldi, S.; Calura, E.; Beltrame, L.; Fuso Nerini, I.; Marchini, S.; Cavalieri, D.; Erba, E.; Chiorino, G.; Ostano, P.; D'Angelo, D.; et al. A systems biology approach to characterize the regulatory networks leading to trabectedin resistance in an in vitro model of myxoid liposarcoma. PLoS One 2012, 7, e35423.
    • (2012) PLoS One , vol.7 , pp. e35423
    • Uboldi, S.1    Calura, E.2    Beltrame, L.3    Fuso Nerini, I.4    Marchini, S.5    Cavalieri, D.6    Erba, E.7    Chiorino, G.8    Ostano, P.9    D'Angelo, D.10
  • 20
    • 0036387382 scopus 로고    scopus 로고
    • Pharmacokinetics of ecteinascidin 743 administered as a 24-h continuous intravenous infusion to adult patients with soft tissue sarcomas: Associations with clinical characteristics, pathophysiological variables and toxicity
    • Puchalski, T.; Ryan, D.; Garcia-Carbonero, R.; Demetri, G.; Butkiewicz, L.; Harmon, D.; Seiden, M.; Maki, R.; Lopez-Lazaro, L.; Jimeno, J.; et al. Pharmacokinetics of ecteinascidin 743 administered as a 24-h continuous intravenous infusion to adult patients with soft tissue sarcomas: Associations with clinical characteristics, pathophysiological variables and toxicity. Cancer Chemother. Pharmacol. 2002, 50, 309-319.
    • (2002) Cancer Chemother. Pharmacol. , vol.50 , pp. 309-319
    • Puchalski, T.1    Ryan, D.2    Garcia-Carbonero, R.3    Demetri, G.4    Butkiewicz, L.5    Harmon, D.6    Seiden, M.7    Maki, R.8    Lopez-Lazaro, L.9    Jimeno, J.10
  • 21
    • 0035127175 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of ecteinascidin 743 administered as a 72-h continuous intravenous infusion in patients with solid malignancies
    • Ryan, D.P.; Supko, J.G.; Eder, J.P.; Seiden, M.V.; Demetri, G.; Lynch, T.J.; Fischman, A.J.; Davis, J.; Jimeno, J.; Clark, J.W. Phase I and pharmacokinetic study of ecteinascidin 743 administered as a 72-h continuous intravenous infusion in patients with solid malignancies. Clin. Cancer Res. 2001, 7, 231-242.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 231-242
    • Ryan, D.P.1    Supko, J.G.2    Eder, J.P.3    Seiden, M.V.4    Demetri, G.5    Lynch, T.J.6    Fischman, A.J.7    Davis, J.8    Jimeno, J.9    Clark, J.W.10
  • 22
    • 0035281641 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of ecteinascidin-743, a new marine compound, administered as a 24-h continuous infusion in patients with solid tumors
    • Taamma, A.; Misset, J.L.; Riofrio, M.; Guzman, C.; Brain, E.; Lopez Lazaro, L.; Rosing, H.; Jimeno, J.M.; Cvitkovic, E. Phase I and pharmacokinetic study of ecteinascidin-743, a new marine compound, administered as a 24-h continuous infusion in patients with solid tumors. J. Clin. Oncol. 2001, 19, 1256-1265.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 1256-1265
    • Taamma, A.1    Misset, J.L.2    Riofrio, M.3    Guzman, C.4    Brain, E.5    Lopez Lazaro, L.6    Rosing, H.7    Jimeno, J.M.8    Cvitkovic, E.9
  • 23
    • 0142121506 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of yondelis™ (ecteinascidin-743; et-743) administered as an infusion over 1 h or 3 h every 21 days in patients with solid tumours
    • Twelves, C.; Hoekman, K.; Bowman, A.; Vermorken, J.B.; Anthoney, A.; Smyth, J.; van Kesteren, C.; Beijnen, J.H.; Uiters, J.; Wanders, J.; et al. Phase I and pharmacokinetic study of yondelis™ (ecteinascidin-743; et-743) administered as an infusion over 1 h or 3 h every 21 days in patients with solid tumours. Eur. J. Cancer 2003, 39, 1842-1851.
    • (2003) Eur. J. Cancer , vol.39 , pp. 1842-1851
    • Twelves, C.1    Hoekman, K.2    Bowman, A.3    Vermorken, J.B.4    Anthoney, A.5    Smyth, J.6    Van Kesteren, C.7    Beijnen, J.H.8    Uiters, J.9    Wanders, J.10
  • 32
    • 53049092830 scopus 로고    scopus 로고
    • A phase I study of the safety and pharmacokinetics of trabectedin in combination with pegylated liposomal doxorubicin in patients with advanced malignancies
    • Von Mehren, M.; Schilder, R.J.; Cheng, J.D.; Temmer, E.; Cardoso, T.M.; Renshaw, F.G.; Bayever, E.; Zannikos, P.; Yuan, Z.; Cohen, R.B. A phase I study of the safety and pharmacokinetics of trabectedin in combination with pegylated liposomal doxorubicin in patients with advanced malignancies. Ann. Oncol. 2008, 19, 1802-1809.
    • (2008) Ann. Oncol. , vol.19 , pp. 1802-1809
    • Von Mehren, M.1    Schilder, R.J.2    Cheng, J.D.3    Temmer, E.4    Cardoso, T.M.5    Renshaw, F.G.6    Bayever, E.7    Zannikos, P.8    Yuan, Z.9    Cohen, R.B.10
  • 36
    • 20044372153 scopus 로고    scopus 로고
    • Phase ii study of et-743 in advanced soft tissue sarcomas: A european organisation for the research and treatment of cancer (eortc) soft tissue and bone sarcoma group trial
    • Le Cesne, A.; Blay, J.Y.; Judson, I.; Van Oosterom, A.; Verweij, J.; Radford, J.; Lorigan, P.; Rodenhuis, S.; Ray-Coquard, I.; Bonvalot, S.; et al. Phase ii study of et-743 in advanced soft tissue sarcomas: A european organisation for the research and treatment of cancer (eortc) soft tissue and bone sarcoma group trial. J. Clin. Oncol. 2005, 23, 576-584.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 576-584
    • Le Cesne, A.1    Blay, J.Y.2    Judson, I.3    Van Oosterom, A.4    Verweij, J.5    Radford, J.6    Lorigan, P.7    Rodenhuis, S.8    Ray-Coquard, I.9    Bonvalot, S.10
  • 38
    • 70249101414 scopus 로고    scopus 로고
    • Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: Results of a randomized phase ii study of two different schedules
    • Demetri, G.D.; Chawla, S.P.; von Mehren, M.; Ritch, P.; Baker, L.H.; Blay, J.Y.; Hande, K.R.; Keohan, M.L.; Samuels, B.L.; Schuetze, S.; et al. Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: Results of a randomized phase ii study of two different schedules. J. Clin. Oncol. 2009, 27, 4188-4196.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 4188-4196
    • Demetri, G.D.1    Chawla, S.P.2    Von Mehren, M.3    Ritch, P.4    Baker, L.H.5    Blay, J.Y.6    Hande, K.R.7    Keohan, M.L.8    Samuels, B.L.9    Schuetze, S.10
  • 40
    • 84878445731 scopus 로고    scopus 로고
    • Clinical outcomes and safety with trabectedin therapy in patients with advanced soft tissue sarcomas following failure of prior chemotherapy: Results of a worldwide expanded access program study
    • Samuels, B.L.; Chawla, S.; Patel, S.; von Mehren, M.; Hamm, J.; Kaiser, P.E.; Schuetze, S.; Li, J.; Aymes, A.; Demetri, G.D. Clinical outcomes and safety with trabectedin therapy in patients with advanced soft tissue sarcomas following failure of prior chemotherapy: Results of a worldwide expanded access program study. Ann. Oncol. 2013, 24, 1703-1709.
    • (2013) Ann. Oncol. , vol.24 , pp. 1703-1709
    • Samuels, B.L.1    Chawla, S.2    Patel, S.3    Von Mehren, M.4    Hamm, J.5    Kaiser, P.E.6    Schuetze, S.7    Li, J.8    Aymes, A.9    Demetri, G.D.10
  • 45
    • 83055194284 scopus 로고    scopus 로고
    • A phase II evaluation of trabectedin in the treatment of advanced, persistent, or recurrent uterine leiomyosarcoma: A gynecologic oncology group study
    • Monk, B.J.; Blessing, J.A.; Street, D.G.; Muller, C.Y.; Burke, J.J.; Hensley, M.L. A phase II evaluation of trabectedin in the treatment of advanced, persistent, or recurrent uterine leiomyosarcoma: A gynecologic oncology group study. Gynecol. Oncol. 2012, 124, 48-52.
    • (2012) Gynecol. Oncol. , vol.124 , pp. 48-52
    • Monk, B.J.1    Blessing, J.A.2    Street, D.G.3    Muller, C.Y.4    Burke, J.J.5    Hensley, M.L.6
  • 46
    • 84885175708 scopus 로고    scopus 로고
    • Trabectedin is a feasible treatment for soft tissue sarcoma patients regardless of patient age: A retrospective pooled analysis of five phase ii trials
    • Cesne, A.L.; Judson, I.; Maki, R.; Grosso, F.; Schuetze, S.; Mehren, M.V.; Chawla, S.P.; Demetri, G.D.; Nieto, A.; Tanovic, A.; et al. Trabectedin is a feasible treatment for soft tissue sarcoma patients regardless of patient age: A retrospective pooled analysis of five phase ii trials. Br. J. Cancer 2013, 109, 1717-1724.
    • (2013) Br. J. Cancer , vol.109 , pp. 1717-1724
    • Cesne, A.L.1    Judson, I.2    Maki, R.3    Grosso, F.4    Schuetze, S.5    Mehren, M.V.6    Chawla, S.P.7    Demetri, G.D.8    Nieto, A.9    Tanovic, A.10


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