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Volumn 33, Issue 3, 2015, Pages 70-77

Incidence and risk of high-grade stomatitis with mTOR inhibitors in cancer patients

Author keywords

Cancer; Everolimus; mTOR inhibitor; mTOR inhibitor associated stomatitis (mIAS); Stomatitis; Temsirolimus

Indexed keywords

EVEROLIMUS; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; TEMSIROLIMUS; MTOR PROTEIN, HUMAN; RAPAMYCIN; TARGET OF RAPAMYCIN KINASE;

EID: 84923206499     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.3109/07357907.2014.1001893     Document Type: Article
Times cited : (28)

References (33)
  • 1
    • 80054099469 scopus 로고    scopus 로고
    • Emerging roles for mammalian target of rapamycin inhibitors in the treatment of solid tumors and hematological malignancies
    • Khokhar NZ, Altman JK, Platanias LC. Emerging roles for mammalian target of rapamycin inhibitors in the treatment of solid tumors and hematological malignancies. Curr Opin Oncol 2011;23:578-586.
    • (2011) Curr Opin Oncol , vol.23 , pp. 578-586
    • Khokhar, N.Z.1    Altman, J.K.2    Platanias, L.C.3
  • 2
    • 84859999866 scopus 로고    scopus 로고
    • mTOR signaling pathway and mTOR inhibitors in cancer therapy
    • Gomez-Pinillos A, Ferrari AC. mTOR signaling pathway and mTOR inhibitors in cancer therapy. Hematol Oncol Clin North Am 2012;26:483-505.
    • (2012) Hematol Oncol Clin North Am , vol.26 , pp. 483-505
    • Gomez-Pinillos, A.1    Ferrari, A.C.2
  • 4
    • 72849150434 scopus 로고    scopus 로고
    • Targeting tumorigenesis: Development and use of mTOR inhibitors in cancer therapy
    • Yuan R, Kay A, Berg WJ, Lebwohl D. Targeting tumorigenesis: development and use of mTOR inhibitors in cancer therapy. J Hematol Oncol 2009;2:45.
    • (2009) J Hematol Oncol , vol.2 , pp. 45
    • Yuan, R.1    Kay, A.2    Berg, W.J.3    Lebwohl, D.4
  • 5
    • 18144399578 scopus 로고    scopus 로고
    • mTOR-targeted therapy of cancer with rapamycin derivatives
    • Vignot S, Faivre S, Aguirre D, Raymond E. mTOR-targeted therapy of cancer with rapamycin derivatives. Ann Oncol 2005;16:525-537.
    • (2005) Ann Oncol , vol.16 , pp. 525-537
    • Vignot, S.1    Faivre, S.2    Aguirre, D.3    Raymond, E.4
  • 6
    • 84905037265 scopus 로고    scopus 로고
    • Rash to the mTOR Inhibitor Everolimus Systematic Review and Meta-Analysis
    • Ramirez-Fort MK, Case EC, Rosen AC et al. Rash to the mTOR Inhibitor Everolimus Systematic Review and Meta-Analysis. Am J Clinc Oncol 2012;37(3):266-71.
    • (2012) Am J Clinc Oncol , vol.37 , Issue.3 , pp. 266-271
    • Ramirez-Fort, M.K.1    Case, E.C.2    Rosen, A.C.3
  • 7
    • 67349127898 scopus 로고    scopus 로고
    • The emerging safety profile of mTOR inhibitors, a novel class of anticancer agents
    • Sankhala K, Mita A, Kelly K et al. The emerging safety profile of mTOR inhibitors, a novel class of anticancer agents. Target Oncol 2009;4:135-142
    • (2009) Target Oncol , vol.4 , pp. 135-142
    • Sankhala, K.1    Mita, A.2    Kelly, K.3
  • 8
    • 84874027374 scopus 로고    scopus 로고
    • Phase II study of docetaxel in combination with everolimus for second- or third-line therapy of advanced non-small-cell lung cancer
    • Ramalingam SS, Owanikoko TK, Behera M et al. Phase II study of docetaxel in combination with everolimus for second- or third-line therapy of advanced non-small-cell lung cancer. J Thorac Oncol 2013;8:369-372.
    • (2013) J Thorac Oncol , vol.8 , pp. 369-372
    • Ramalingam, S.S.1    Owanikoko, T.K.2    Behera, M.3
  • 9
    • 78649592049 scopus 로고    scopus 로고
    • A phase 2 study of the oral mammalian target of rapamycin inhibitor, everolimus, in patients with recurrent endometrial carcinoma
    • Slomovitz BM, Lu KH, Johnston T et al. A phase 2 study of the oral mammalian target of rapamycin inhibitor, everolimus, in patients with recurrent endometrial carcinoma. Cancer 2010;116:5415-5419.
    • (2010) Cancer , vol.116 , pp. 5415-5419
    • Slomovitz, B.M.1    Lu, K.H.2    Johnston, T.3
  • 10
    • 80052010923 scopus 로고    scopus 로고
    • Phase II study of temsirolimus in women with recurrent or metastatic endometrial cancer: A trial of the NCIC Clinical Trials Group
    • Oza AM, Elit L, Tsao MS et al. Phase II study of temsirolimus in women with recurrent or metastatic endometrial cancer: a trial of the NCIC Clinical Trials Group. J Clin Oncol 2011;29: 3278-3285.
    • (2011) J Clin Oncol , vol.29 , pp. 3278-3285
    • Oza, A.M.1    Elit, L.2    Tsao, M.S.3
  • 11
    • 79960698959 scopus 로고    scopus 로고
    • A phase 2 study of temsirolimus (CCI-779) in patients with soft tissue sarcomas: A study of the Mayo phase 2 consortium (P2C)
    • Okuno S, Bailey H, Mahoney MR et al. A phase 2 study of temsirolimus (CCI-779) in patients with soft tissue sarcomas: a study of the Mayo phase 2 consortium (P2C). Cancer 2011;117:3468-3475.
    • (2011) Cancer , vol.117 , pp. 3468-3475
    • Okuno, S.1    Bailey, H.2    Mahoney, M.R.3
  • 12
    • 49049087320 scopus 로고    scopus 로고
    • Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: A phase 2 trial in the North Central Cancer Treatment Group
    • Ansell SM, Inwards DJ, Rowland KM Jr et al. Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: a phase 2 trial in the North Central Cancer Treatment Group. Cancer 2008;113:508-514.
    • (2008) Cancer , vol.113 , pp. 508-514
    • Ansell, S.M.1    Inwards, D.J.2    Rowland, K.M.3
  • 13
    • 84863971730 scopus 로고    scopus 로고
    • A multicenter phase II trial (SAKK 36/06) of single-agent everolimus (RAD001) in patients with relapsed or refractory mantle cell lymphoma
    • Renner C, Zinzani PL, Gressin R et al. A multicenter phase II trial (SAKK 36/06) of single-agent everolimus (RAD001) in patients with relapsed or refractory mantle cell lymphoma. Haematologica 2012;97:1085-1091.
    • (2012) Haematologica , vol.97 , pp. 1085-1091
    • Renner, C.1    Zinzani, P.L.2    Gressin, R.3
  • 14
    • 68949102180 scopus 로고    scopus 로고
    • Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma
    • Hess G, Herbrecht R, Romaguera J et al. Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma. J Clin Oncol 2009;27:3822-3829.
    • (2009) J Clin Oncol , vol.27 , pp. 3822-3829
    • Hess, G.1    Herbrecht, R.2    Romaguera, J.3
  • 15
    • 84875257898 scopus 로고    scopus 로고
    • A review of oral toxicity associated with mTOR inhibitor therapy in cancer patients
    • Martins F, de Oliveira MA, Wang Q et al. A review of oral toxicity associated with mTOR inhibitor therapy in cancer patients. Oral Oncol 2013;49:293-298.
    • (2013) Oral Oncol , vol.49 , pp. 293-298
    • Martins, F.1    De Oliveira, M.A.2    Wang, Q.3
  • 16
    • 74549192779 scopus 로고    scopus 로고
    • Preliminary characterization of oral lesions associated with inhibitors of mammalian target of rapamycin in cancer patients
    • Sonis S, Treister N, Chawla S et al. Preliminary characterization of oral lesions associated with inhibitors of mammalian target of rapamycin in cancer patients. Cancer 2010;116:210-215.
    • (2010) Cancer , vol.116 , pp. 210-215
    • Sonis, S.1    Treister, N.2    Chawla, S.3
  • 18
    • 0029914622 scopus 로고    scopus 로고
    • Assessing the quality of reports of randomized clinical trials
    • Jadad AR, Moore RA, Carroll D et al. Assessing the quality of reports of randomized clinical trials. Control Clin Trials 1996;17:1-12.
    • (1996) Control Clin Trials , vol.17 , pp. 1-12
    • Jadad, A.R.1    Moore, R.A.2    Carroll, D.3
  • 19
    • 79851500081 scopus 로고    scopus 로고
    • Everolimus for advanced pancreatic neuroendocrine tumors
    • Yao JC, Shah MH, Ito T et al. Everolimus for advanced pancreatic neuroendocrine tumors. New Engl J Med 2011;364:514-523.
    • (2011) New Engl J Med , vol.364 , pp. 514-523
    • Yao, J.C.1    Shah, M.H.2    Ito, T.3
  • 20
    • 84874746597 scopus 로고    scopus 로고
    • Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis placebo-controlled trial
    • Bissler JJ, Kingswood JC, Radzikowska E et al. Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis placebo-controlled trial. Lancet 2013;381:817-824.
    • (2013) Lancet , vol.381 , pp. 817-824
    • Bissler, J.J.1    Kingswood, J.C.2    Radzikowska, E.3
  • 21
    • 84891371392 scopus 로고    scopus 로고
    • Everolimus for Previously Treated Advanced Gastric Cancer: Results of the Randomized, Double-Blind, Phase III GRANITE-1 Study
    • Ohtsu A, Ajani JA, Bai YX et al. Everolimus for Previously Treated Advanced Gastric Cancer: Results of the Randomized, Double-Blind, Phase III GRANITE-1 Study. J Clin Oncol 2013;31:3935-3943.
    • (2013) J Clin Oncol , vol.31 , pp. 3935-3943
    • Ohtsu, A.1    Ajani, J.A.2    Bai, Y.X.3
  • 22
    • 77956227464 scopus 로고    scopus 로고
    • Phase 3 trial of everolimus for metastatic renal cell carcinoma: Final results and analysis of prognostic factors
    • Motzer RJ, Escudier B, Oudard S et al. Phase 3 trial of everolimus for metastatic renal cell carcinoma: final results and analysis of prognostic factors. Cancer 2010;116:4256-4265.
    • (2010) Cancer , vol.116 , pp. 4256-4265
    • Motzer, R.J.1    Escudier, B.2    Oudard, S.3
  • 23
    • 84872088946 scopus 로고    scopus 로고
    • Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex phase 3 trial
    • Franz DN, Belousova E, Sparagana S et al. Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex phase 3 trial. Lancet 2013;1:125-132.
    • (2013) Lancet , vol.1 , pp. 125-132
    • Franz, D.N.1    Belousova, E.2    Sparagana, S.3
  • 24
    • 84863078767 scopus 로고    scopus 로고
    • Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer
    • Baselga J, Campone M, Piccart M et al. Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer. N Engl J Med 2012;366:520-529.
    • (2012) N Engl J Med , vol.366 , pp. 520-529
    • Baselga, J.1    Campone, M.2    Piccart, M.3
  • 25
    • 84864558874 scopus 로고    scopus 로고
    • Randomized phase II trial of everolimus in combination with tamoxifen in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer with prior exposure to aromatase inhibitors: A GINECO study
    • Bachelot T, Bourgier C, Cropet C et al. Randomized phase II trial of everolimus in combination with tamoxifen in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer with prior exposure to aromatase inhibitors: a GINECO study. J Clin Oncol 2012;30:2718-2724.
    • (2012) J Clin Oncol , vol.30 , pp. 2718-2724
    • Bachelot, T.1    Bourgier, C.2    Cropet, C.3
  • 26
    • 66849136781 scopus 로고    scopus 로고
    • Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer
    • Baselga J, Semiglazov V, van Dam P et al. Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer. J Clin Oncol 2009;27:2630-2637.
    • (2009) J Clin Oncol , vol.27 , pp. 2630-2637
    • Baselga, J.1    Semiglazov, V.2    Van Dam, P.3
  • 27
    • 83255167036 scopus 로고    scopus 로고
    • Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2): A randomised, placebo-controlled, phase 3 study
    • Pavel ME, Hainsworth JD, Baudin E et al. Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2): a randomised, placebo-controlled, phase 3 study. Lancet 2011;378:2005-2012.
    • (2011) Lancet , vol.378 , pp. 2005-2012
    • Pavel, M.E.1    Hainsworth, J.D.2    Baudin, E.3
  • 28
    • 34249779568 scopus 로고    scopus 로고
    • Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
    • Hudes G, Carducci M, Tomczak P et al. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med 2007;356:2271-2281.
    • (2007) N Engl J Med , vol.356 , pp. 2271-2281
    • Hudes, G.1    Carducci, M.2    Tomczak, P.3
  • 29
    • 84872518645 scopus 로고    scopus 로고
    • Randomized phase III placebo-controlled trial of letrozole plus oral temsirolimus as firstline endocrine therapy in postmenopausal women with locally advanced or metastatic breast cancer
    • Wolff AC, Lazar AA, Bondarenko I et al. Randomized phase III placebo-controlled trial of letrozole plus oral temsirolimus as firstline endocrine therapy in postmenopausal women with locally advanced or metastatic breast cancer. J Clin Oncol 2013;31:195-202.
    • (2013) J Clin Oncol , vol.31 , pp. 195-202
    • Wolff, A.C.1    Lazar, A.A.2    Bondarenko, I.3
  • 30
    • 80053959068 scopus 로고    scopus 로고
    • Clinical presentation and management of mTOR inhibitor-associated stomatitis
    • de Oliveira MA, Martins F, Martins E et al. Clinical presentation and management of mTOR inhibitor-associated stomatitis. Oral Oncol 2011;47:998-1003.
    • (2011) Oral Oncol , vol.47 , pp. 998-1003
    • De Oliveira, M.A.1    Martins, F.2    Martins, E.3
  • 31
    • 84856212971 scopus 로고    scopus 로고
    • The risk of skin rash and stomatitis with the mammalian target of rapamycin inhibitor temsirolimus: A systematic review of the literature and meta-analysis
    • Gomez-Fernandez C, Garden BC, Wu S et al. The risk of skin rash and stomatitis with the mammalian target of rapamycin inhibitor temsirolimus: a systematic review of the literature and meta-analysis. Eur J Cancer 2012;48:340-346.
    • (2012) Eur J Cancer , vol.48 , pp. 340-346
    • Gomez-Fernandez, C.1    Garden, B.C.2    Wu, S.3
  • 32
    • 33748530840 scopus 로고    scopus 로고
    • Randomized 3-arm, phase 2 study of temsirolimus (CCL-779) in combination with letrozole in post-menopausal women with locally advanced or metastatic breast cancer
    • Carpenter JT, Roche H, Campone M et al. Randomized 3-arm, phase 2 study of temsirolimus (CCL-779) in combination with letrozole in post-menopausal women with locally advanced or metastatic breast cancer. J Clin Oncol 2005;23:19s (suppl 16; abstr 564).
    • (2005) J Clin Oncol , vol.23 , pp. 19s
    • Carpenter, J.T.1    Roche, H.2    Campone, M.3
  • 33
    • 79957566962 scopus 로고    scopus 로고
    • Management of adverse effects associated with the use of everolimus in patients with advanced renal cell carcinoma
    • Porta C, Osanto S, Ravoud A et al. Management of adverse effects associated with the use of everolimus in patients with advanced renal cell carcinoma. Eur J Cancer 2011;47:1287-1298.
    • (2011) Eur J Cancer , vol.47 , pp. 1287-1298
    • Porta, C.1    Osanto, S.2    Ravoud, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.