In vivo evaluation of atherosclerotic plaques and culprit lesions using noninvasive techniques

Nature Reviews Cardiology

Volumn 12, Issue 2, 2015, Pages 79-

  Caobelli, Federico ^a   Bengel, Frank M ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORODEOXYGLUCOSE F 18; RADIOISOTOPE; TRACER; RADIOPHARMACEUTICAL AGENT;

ANGIOCARDIOGRAPHY; ANGIOGENESIS; ATHEROSCLEROTIC PLAQUE; BLOOD VESSEL WALL; CLINICAL EVALUATION; CLINICAL PRACTICE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY OBSTRUCTION; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE SEVERITY; DRUG HALF LIFE; DRUG UPTAKE; GOLD STANDARD; HUMAN; LETTER; LEUKOCYTE; LYMPHOCYTIC INFILTRATION; MOLECULAR IMAGING; NON INVASIVE PROCEDURE; PET-CT SCANNER; PREDICTIVE VALUE; PRIORITY JOURNAL; PROGNOSIS; RADIATION EXPOSURE; RADIOCHEMISTRY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SOLID STATE; ATHEROSCLEROSIS; DIAGNOSTIC USE; INFLAMMATION; POSITRON EMISSION TOMOGRAPHY; SCINTISCANNING;

ATHEROSCLEROSIS; HUMANS; INFLAMMATION; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS;

EID: 84923124907     PISSN: 17595002     EISSN: 17595010     Source Type: Journal    
DOI: 10.1038/nrcardio.2014.80-c1     Document Type: Letter

References (12)

1. Fleg, J. L. et al. Detection of high-risk atherosclerotic plaque: report of the NHLBI Working Group on current status and future directions. JACC Cardiovasc. Imaging 5, 941-955 (2012).
2. Naghavi, M. et al. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: part I. Circulation 108, 1664-1672 (2003).
3. Tarkin, J. M., Joshi, F. R. & Rudd, J. H. F. PET imaging of inflammation in atherosclerosis. Nat. Rev. Cardiol. 11, 443-457 (2014).
4. Rudd, J. H. et al. 18Fluorodeoxyglucose positron emission tomography imaging of atherosclerotic plaque inflammation is highly reproducible: implications for atherosclerosis therapy trials. J. Am. Coll. Cardiol. 50, 892-896 (2007).
5. Joshi, N. V. et al. 18F-fluoride positron emission tomography for identification of ruptured and high-risk coronary atherosclerotic plaques: a prospective clinical trial. Lancet 383, 705-713 (2014).
6. Schatka, I. et al. Peptide receptor-targeted radionuclide therapy alters inflammation in atherosclerotic plaques. J. Am. Coll. Cardiol. 62, 2344-2345 (2013).
7. Tio, R. A. et al. Comparison between the prognostic value of left ventricular function and myocardial perfusion reserve in patients with ischemic heart disease. J. Nucl. Med. 50, 214-219 (2009).
8. Imbert, L. et al. Compared performance of high-sensitivity cameras dedicated to myocardial perfusion SPECT: a comprehensive analysis of phantom and human images. J. Nucl. Med. 53, 1897-1903 (2012).
9. van der Valk, F. M. et al. In vivo imaging of enhanced leukocyte accumulation in atherosclerotic lesions in humans. J. Am. Coll. Cardiol. 64, 1019-1029 (2014).
10. Glaudemans, A. W. et al. In vivo and in vitro evidence that 99mTc-HYNIC-interleukin-2 is able to detect T lymphocytes in vulnerable atherosclerotic plaques of the carotid artery. Eur. J. Nucl. Med. Mol. Imaging 41, 1710-1719 (2014).
11. Zhang, R. et al. Annexin A5-conjugated polymeric micelles for dual SPECT and optical detection of apoptosis. J. Nucl. Med. 52, 958-964 (2011).
12. Terry, S. Y. et al. Imaging integrin αvβ3 on blood vessels with 111In-RGD2 in head and neck tumor xenografts. J. Nucl. Med. 55, 281-286 (2014).