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Volumn 51, Issue 3, 2015, Pages 247-253

Upregulation of osteoprotegerin expression correlates with bone invasion and predicts poor clinical outcome in oral cancer

Author keywords

Neoadjuvant therapy; Oral cancer; Osteoprotegerin; Prognosis; RANK ligand; Receptor activator of nuclear factor kappa B

Indexed keywords

ANTINEOPLASTIC AGENT; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TUMOR MARKER;

EID: 84923116979     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2014.11.010     Document Type: Article
Times cited : (20)

References (40)
  • 1
    • 67349186933 scopus 로고    scopus 로고
    • Global epidemiology of oral and oropharyngeal cancer
    • S. Warnakulasuriya Global epidemiology of oral and oropharyngeal cancer Oral Oncol 45 2009 309 316
    • (2009) Oral Oncol , vol.45 , pp. 309-316
    • Warnakulasuriya, S.1
  • 3
    • 9244252016 scopus 로고    scopus 로고
    • The molecular triad OPG/RANK/RANKL: Involvement in the orchestration of pathophysiological bone remodeling
    • S. Theoleyre, Y. Wittrant, S.K. Tat, Y. Fortun, F. Redini, and D. Heymann The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodeling Cytokine Growth Factor Rev 15 2004 457 475
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 457-475
    • Theoleyre, S.1    Wittrant, Y.2    Tat, S.K.3    Fortun, Y.4    Redini, F.5    Heymann, D.6
  • 4
    • 84862884060 scopus 로고    scopus 로고
    • Crystal structure of human RANKL complexed with its decoy receptor osteoprotegerin
    • X. Luan, Q. Lu, Y. Jiang, S. Zhang, Q. Wang, and H. Yuan Crystal structure of human RANKL complexed with its decoy receptor osteoprotegerin J Immunol 189 2012 245 252
    • (2012) J Immunol , vol.189 , pp. 245-252
    • Luan, X.1    Lu, Q.2    Jiang, Y.3    Zhang, S.4    Wang, Q.5    Yuan, H.6
  • 5
    • 0031005576 scopus 로고    scopus 로고
    • Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
    • W.S. Simonet, D.L. Lacey, C.R. Dunstan, M. Kelley, M.S. Chang, and R. Luthy Osteoprotegerin: a novel secreted protein involved in the regulation of bone density Cell 89 1997 309 319
    • (1997) Cell , vol.89 , pp. 309-319
    • Simonet, W.S.1    Lacey, D.L.2    Dunstan, C.R.3    Kelley, M.4    Chang, M.S.5    Luthy, R.6
  • 6
    • 79955772442 scopus 로고    scopus 로고
    • Receptor activator of NF-kB (RANK) expression in primary tumors associates with bone metastasis occurrence in breast cancer patients
    • D. Santini, G. Schiavon, B. Vincenzi, L. Gaeta, F. Pantano, and A. Russo Receptor activator of NF-kB (RANK) expression in primary tumors associates with bone metastasis occurrence in breast cancer patients PLoS One 6 2011 e19234
    • (2011) PLoS One , vol.6 , pp. e19234
    • Santini, D.1    Schiavon, G.2    Vincenzi, B.3    Gaeta, L.4    Pantano, F.5    Russo, A.6
  • 7
    • 33745821237 scopus 로고    scopus 로고
    • Expression of RANKL/RANK/OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation
    • G. Chen, K. Sircar, A. Aprikian, A. Potti, D. Goltzman, and S.A. Rabbani Expression of RANKL/RANK/OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation Cancer 107 2006 289 298
    • (2006) Cancer , vol.107 , pp. 289-298
    • Chen, G.1    Sircar, K.2    Aprikian, A.3    Potti, A.4    Goltzman, D.5    Rabbani, S.A.6
  • 9
    • 84874883241 scopus 로고    scopus 로고
    • Differential expression of the RANKL/RANK/OPG system is associated with bone metastasis in human non-small cell lung cancer
    • X. Peng, W. Guo, T. Ren, Z. Lou, X. Lu, and S. Zhang Differential expression of the RANKL/RANK/OPG system is associated with bone metastasis in human non-small cell lung cancer PLoS One 8 2013 e58361
    • (2013) PLoS One , vol.8 , pp. e58361
    • Peng, X.1    Guo, W.2    Ren, T.3    Lou, Z.4    Lu, X.5    Zhang, S.6
  • 10
    • 84873833526 scopus 로고    scopus 로고
    • TRAIL and osteoprotegerin (OPG) expression in bladder urothelial carcinoma: Correlation with clinicopathological parameters and prognosis
    • G. Levidou, I. Thymara, A.A. Saetta, P. Papanastasiou, P. Pavlopoulos, and S. Sakellariou TRAIL and osteoprotegerin (OPG) expression in bladder urothelial carcinoma: correlation with clinicopathological parameters and prognosis Pathology 45 2013 138 144
    • (2013) Pathology , vol.45 , pp. 138-144
    • Levidou, G.1    Thymara, I.2    Saetta, A.A.3    Papanastasiou, P.4    Pavlopoulos, P.5    Sakellariou, S.6
  • 11
    • 0041854146 scopus 로고    scopus 로고
    • Expression of osteoprotegerin correlates with aggressiveness and poor prognosis of gastric carcinoma
    • R. Ito, H. Nakayama, K. Yoshida, K. Kuraoka, J. Motoshita, and N. Oda Expression of osteoprotegerin correlates with aggressiveness and poor prognosis of gastric carcinoma Virchows Arch 443 2003 146 151
    • (2003) Virchows Arch , vol.443 , pp. 146-151
    • Ito, R.1    Nakayama, H.2    Yoshida, K.3    Kuraoka, K.4    Motoshita, J.5    Oda, N.6
  • 13
    • 84872361584 scopus 로고    scopus 로고
    • Oral squamous carcinoma cells secrete RANKL directly supporting osteolytic bone loss
    • X. Zhang, C.R. Junior, M. Liu, F. Li, N.J. D'Silva, and K.L. Kirkwood Oral squamous carcinoma cells secrete RANKL directly supporting osteolytic bone loss Oral Oncol 49 2013 119 128
    • (2013) Oral Oncol , vol.49 , pp. 119-128
    • Zhang, X.1    Junior, C.R.2    Liu, M.3    Li, F.4    D'Silva, N.J.5    Kirkwood, K.L.6
  • 14
    • 84901983312 scopus 로고    scopus 로고
    • Managing bone metastases and reducing skeletal related events in prostate cancer
    • B.A. Gartrell, and F. Saad Managing bone metastases and reducing skeletal related events in prostate cancer Nat Rev Clin Oncol 11 2014 335 345
    • (2014) Nat Rev Clin Oncol , vol.11 , pp. 335-345
    • Gartrell, B.A.1    Saad, F.2
  • 15
    • 84883447180 scopus 로고    scopus 로고
    • Activation of NF-kappaB by the RANKL/RANK system up-regulates snail and twist expressions and induces epithelial-to-mesenchymal transition in mammary tumor cell lines
    • M. Tsubaki, M. Komai, S. Fujimoto, T. Itoh, M. Imano, and K. Sakamoto Activation of NF-kappaB by the RANKL/RANK system up-regulates snail and twist expressions and induces epithelial-to-mesenchymal transition in mammary tumor cell lines J Exp Clin Cancer Res 32 2013 62
    • (2013) J Exp Clin Cancer Res , vol.32 , pp. 62
    • Tsubaki, M.1    Komai, M.2    Fujimoto, S.3    Itoh, T.4    Imano, M.5    Sakamoto, K.6
  • 16
    • 84899531840 scopus 로고    scopus 로고
    • Markers of epithelial to mesenchymal transition in association with survival in head and neck squamous cell carcinoma (HNSCC)
    • E. Pectasides, T. Rampias, C. Sasaki, C. Perisanidis, V. Kouloulias, and B. Burtness Markers of epithelial to mesenchymal transition in association with survival in head and neck squamous cell carcinoma (HNSCC) PLoS One 9 2014 e94273
    • (2014) PLoS One , vol.9 , pp. e94273
    • Pectasides, E.1    Rampias, T.2    Sasaki, C.3    Perisanidis, C.4    Kouloulias, V.5    Burtness, B.6
  • 17
    • 84887954786 scopus 로고    scopus 로고
    • Osteoprotegerin (OPG) activates integrin, focal adhesion kinase (FAK), and Akt signaling in ovarian cancer cells to attenuate TRAIL-induced apoptosis
    • D. Lane, I. Matte, C. Laplante, P. Garde-Granger, C. Rancourt, and A. Piche Osteoprotegerin (OPG) activates integrin, focal adhesion kinase (FAK), and Akt signaling in ovarian cancer cells to attenuate TRAIL-induced apoptosis J Ovarian Res 6 2013 82
    • (2013) J Ovarian Res , vol.6 , pp. 82
    • Lane, D.1    Matte, I.2    Laplante, C.3    Garde-Granger, P.4    Rancourt, C.5    Piche, A.6
  • 18
    • 51049114701 scopus 로고    scopus 로고
    • OPG is regulated by beta-catenin and mediates resistance to TRAIL-induced apoptosis in colon cancer
    • E.N. De Toni, S.E. Thieme, A. Herbst, A. Behrens, P. Stieber, and A. Jung OPG is regulated by beta-catenin and mediates resistance to TRAIL-induced apoptosis in colon cancer Clin Cancer Res 14 2008 4713 4718
    • (2008) Clin Cancer Res , vol.14 , pp. 4713-4718
    • De Toni, E.N.1    Thieme, S.E.2    Herbst, A.3    Behrens, A.4    Stieber, P.5    Jung, A.6
  • 19
    • 22044436505 scopus 로고    scopus 로고
    • Oral squamous cell carcinoma cells induce osteoclast differentiation by suppression of osteoprotegerin expression in osteoblasts
    • T. Tada, E. Jimi, M. Okamoto, S. Ozeki, and K. Okabe Oral squamous cell carcinoma cells induce osteoclast differentiation by suppression of osteoprotegerin expression in osteoblasts Int J Cancer 116 2005 253 262
    • (2005) Int J Cancer , vol.116 , pp. 253-262
    • Tada, T.1    Jimi, E.2    Okamoto, M.3    Ozeki, S.4    Okabe, K.5
  • 20
    • 84861645986 scopus 로고    scopus 로고
    • Characterization of bone resorption in novel in vitro and in vivo models of oral squamous cell carcinoma
    • C.K. Martin, W.P. Dirksen, S.T. Shu, J.L. Werbeck, N.K. Thudi, and M. Yamaguchi Characterization of bone resorption in novel in vitro and in vivo models of oral squamous cell carcinoma Oral Oncol 48 2012 491 499
    • (2012) Oral Oncol , vol.48 , pp. 491-499
    • Martin, C.K.1    Dirksen, W.P.2    Shu, S.T.3    Werbeck, J.L.4    Thudi, N.K.5    Yamaguchi, M.6
  • 21
    • 20244367149 scopus 로고    scopus 로고
    • Effect of YM529 on a model of mandibular invasion by oral squamous cell carcinoma in mice
    • N. Cui, T. Nomura, H. Noma, K. Yokoo, R. Takagi, and S. Hashimoto Effect of YM529 on a model of mandibular invasion by oral squamous cell carcinoma in mice Clin Cancer Res 11 2005 2713 2719
    • (2005) Clin Cancer Res , vol.11 , pp. 2713-2719
    • Cui, N.1    Nomura, T.2    Noma, H.3    Yokoo, K.4    Takagi, R.5    Hashimoto, S.6
  • 22
    • 70350448671 scopus 로고    scopus 로고
    • Immunohistochemical expression of RANKL, RANK, and OPG in human oral squamous cell carcinoma
    • F.H. Chuang, S.S. Hsue, C.W. Wu, and Y.K. Chen Immunohistochemical expression of RANKL, RANK, and OPG in human oral squamous cell carcinoma J Oral Pathol Med 38 2009 753 758
    • (2009) J Oral Pathol Med , vol.38 , pp. 753-758
    • Chuang, F.H.1    Hsue, S.S.2    Wu, C.W.3    Chen, Y.K.4
  • 23
    • 84855905400 scopus 로고    scopus 로고
    • Sonic hedgehog signaling promotes growth of oral squamous cell carcinoma cells associated with bone destruction
    • T. Honami, T. Shimo, T. Okui, N. Kurio, N.M. Hassan, and M. Iwamoto Sonic hedgehog signaling promotes growth of oral squamous cell carcinoma cells associated with bone destruction Oral Oncol 48 2012 49 55
    • (2012) Oral Oncol , vol.48 , pp. 49-55
    • Honami, T.1    Shimo, T.2    Okui, T.3    Kurio, N.4    Hassan, N.M.5    Iwamoto, M.6
  • 24
    • 79957939457 scopus 로고    scopus 로고
    • The cellular and molecular mechanisms of bone invasion by oral squamous cell carcinoma
    • E. Jimi, H. Furuta, K. Matsuo, K. Tominaga, T. Takahashi, and O. Nakanishi The cellular and molecular mechanisms of bone invasion by oral squamous cell carcinoma Oral Dis 17 2011 462 468
    • (2011) Oral Dis , vol.17 , pp. 462-468
    • Jimi, E.1    Furuta, H.2    Matsuo, K.3    Tominaga, K.4    Takahashi, T.5    Nakanishi, O.6
  • 25
    • 84876561185 scopus 로고    scopus 로고
    • RANKL synthesized by both stromal cells and cancer cells plays a crucial role in osteoclastic bone resorption induced by oral cancer
    • K. Sato, J.W. Lee, K. Sakamoto, T. Iimura, K. Kayamori, and H. Yasuda RANKL synthesized by both stromal cells and cancer cells plays a crucial role in osteoclastic bone resorption induced by oral cancer Am J Pathol 182 2013 1890 1899
    • (2013) Am J Pathol , vol.182 , pp. 1890-1899
    • Sato, K.1    Lee, J.W.2    Sakamoto, K.3    Iimura, T.4    Kayamori, K.5    Yasuda, H.6
  • 26
    • 84882471121 scopus 로고    scopus 로고
    • Co-expression of CD44+/RANKL+ tumor cells in the carcinogenesis of oral squamous cell carcinoma
    • Grimm M, Renz C, Munz A, Hoefert S, Krimmel M, Reinert S. Co-expression of CD44+/RANKL+ tumor cells in the carcinogenesis of oral squamous cell carcinoma. Odontology; 2013.
    • (2013) Odontology
    • Grimm, M.1    Renz, C.2    Munz, A.3    Hoefert, S.4    Krimmel, M.5    Reinert, S.6
  • 27
    • 77955190260 scopus 로고    scopus 로고
    • Osteoclast-related cytokines from biopsy specimens predict mandibular invasion by oral squamous cell carcinoma
    • N. Cui, T. Nomura, N. Takano, E. Wang, W. Zhang, and T. Onda Osteoclast-related cytokines from biopsy specimens predict mandibular invasion by oral squamous cell carcinoma Exp Ther Med 1 2010 755 760
    • (2010) Exp Ther Med , vol.1 , pp. 755-760
    • Cui, N.1    Nomura, T.2    Takano, N.3    Wang, E.4    Zhang, W.5    Onda, T.6
  • 30
    • 0024535192 scopus 로고
    • Histologic tumor regression grades in squamous cell carcinoma of the head and neck after preoperative radiochemotherapy
    • O.M. Braun, B. Neumeister, W. Popp, R. Scherrer, E. Dobrowsky, and W. Dobrowsky Histologic tumor regression grades in squamous cell carcinoma of the head and neck after preoperative radiochemotherapy Cancer 63 1989 1097 1100
    • (1989) Cancer , vol.63 , pp. 1097-1100
    • Braun, O.M.1    Neumeister, B.2    Popp, W.3    Scherrer, R.4    Dobrowsky, E.5    Dobrowsky, W.6
  • 31
    • 84875267545 scopus 로고    scopus 로고
    • Impact of epidermal growth factor receptor, mesenchymal-epithelial transition factor, and insulin-like growth factor receptor 1 expression on survival of patients with oral and oropharyngeal cancer
    • C. Perisanidis, F. Wrba, A. Brandstetter, G. Kornek, D. Mitchell, and R. Seemann Impact of epidermal growth factor receptor, mesenchymal-epithelial transition factor, and insulin-like growth factor receptor 1 expression on survival of patients with oral and oropharyngeal cancer Br J Oral Maxillofac Surg 51 2013 234 240
    • (2013) Br J Oral Maxillofac Surg , vol.51 , pp. 234-240
    • Perisanidis, C.1    Wrba, F.2    Brandstetter, A.3    Kornek, G.4    Mitchell, D.5    Seemann, R.6
  • 32
    • 84855311144 scopus 로고    scopus 로고
    • EGFR expression as a predictor of survival for first-line chemotherapy plus cetuximab in patients with advanced non-small-cell lung cancer: Analysis of data from the phase 3 FLEX study
    • R. Pirker, J.R. Pereira, J. von Pawel, M. Krzakowski, R. Ramlau, and K. Park EGFR expression as a predictor of survival for first-line chemotherapy plus cetuximab in patients with advanced non-small-cell lung cancer: analysis of data from the phase 3 FLEX study Lancet Oncol 13 2012 33 42
    • (2012) Lancet Oncol , vol.13 , pp. 33-42
    • Pirker, R.1    Pereira, J.R.2    Von Pawel, J.3    Krzakowski, M.4    Ramlau, R.5    Park, K.6
  • 33
    • 0037374460 scopus 로고    scopus 로고
    • Osteoprotegerin is a soluble decoy receptor for tumor necrosis factor-related apoptosis-inducing ligand/Apo2 ligand and can function as a paracrine survival factor for human myeloma cells
    • C.M. Shipman, and P.I. Croucher Osteoprotegerin is a soluble decoy receptor for tumor necrosis factor-related apoptosis-inducing ligand/Apo2 ligand and can function as a paracrine survival factor for human myeloma cells Cancer Res 63 2003 912 916
    • (2003) Cancer Res , vol.63 , pp. 912-916
    • Shipman, C.M.1    Croucher, P.I.2
  • 36
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • D. Hanahan, and R.A. Weinberg Hallmarks of cancer: the next generation Cell 144 2011 646 674
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 37
    • 52649109068 scopus 로고    scopus 로고
    • The TRAIL apoptotic pathway in cancer onset, progression and therapy
    • R.W. Johnstone, A.J. Frew, and M.J. Smyth The TRAIL apoptotic pathway in cancer onset, progression and therapy Nat Rev Cancer 8 2008 782 798
    • (2008) Nat Rev Cancer , vol.8 , pp. 782-798
    • Johnstone, R.W.1    Frew, A.J.2    Smyth, M.J.3
  • 38
    • 84873411673 scopus 로고    scopus 로고
    • Clinical targeting of the TNF and TNFR superfamilies
    • M. Croft, C.A. Benedict, and C.F. Ware Clinical targeting of the TNF and TNFR superfamilies Nat Rev Drug Discov 12 2013 147 168
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 147-168
    • Croft, M.1    Benedict, C.A.2    Ware, C.F.3
  • 40
    • 84873412457 scopus 로고    scopus 로고
    • MATH, a novel measure of intratumor genetic heterogeneity, is high in poor-outcome classes of head and neck squamous cell carcinoma
    • E.A. Mroz, and J.W. Rocco MATH, a novel measure of intratumor genetic heterogeneity, is high in poor-outcome classes of head and neck squamous cell carcinoma Oral Oncol 49 2013 211 215
    • (2013) Oral Oncol , vol.49 , pp. 211-215
    • Mroz, E.A.1    Rocco, J.W.2


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