Glutathione activates virulence gene expression of an intracellular pathogen

Nature

Volumn 517, Issue 7533, 2015, Pages 170-173

  Reniere, Michelle L ^a   Whiteley, Aaron T ^a   Hamilton, Keri L ^b   John, Sonya M ^a   Lauer, Peter ^c   Brennan, Richard G ^b   Portnoy, Daniel A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Aduro BioTech Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CYCLIC AMP BINDING PROTEIN; GLUTATHIONE; GLUTATHIONE SYNTHASE; PRFA PROTEIN; REGULATOR PROTEIN; THIOL GROUP; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; DNA; PRFA PROTEIN, LISTERIA MONOCYTOGENES; PROTEIN BINDING; TRANSLATION TERMINATION FACTOR;

GENE EXPRESSION; GENETIC ANALYSIS; INFECTIOUS DISEASE; MORBIDITY; MORTALITY; MUTATION; PATHOGEN; VIRULENCE;

ALLOSTERISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL GENOME; BACTERIAL LOAD; BACTERIAL VIRULENCE; BACTERIUM MUTANT; BINDING AFFINITY; BIOCHEMISTRY; CONTROLLED STUDY; FEMALE; GENE ACTIVATION; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC SELECTION; GENOME ANALYSIS; HOMEOSTASIS; IN VIVO STUDY; LISTERIA MONOCYTOGENES; LISTERIOSIS; MACROPHAGE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; SUPPRESSOR GENE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENE REPRESSION; GENETICS; INTRACELLULAR SPACE; METABOLISM; MICROBIOLOGY; MUTATION; PATHOGENICITY; VIRULENCE;

BACTERIA (MICROORGANISMS); LISTERIA MONOCYTOGENES; MAMMALIA; MUS;

ALLOSTERIC REGULATION; BACTERIAL PROTEINS; DNA; GENE EXPRESSION REGULATION, BACTERIAL; GLUTATHIONE; INTRACELLULAR SPACE; LISTERIA MONOCYTOGENES; MACROPHAGES; MUTATION; PEPTIDE TERMINATION FACTORS; PROTEIN BINDING; SELECTION, GENETIC; SUPPRESSION, GENETIC; VIRULENCE;

EID: 84923090650     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14029     Document Type: Article

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