Osteogenesis of bone marrow mesenchymal stem cells on strontium-substituted nano-hydroxyapatite coated roughened titanium surfaces

International Journal of Clinical and Experimental Medicine

Volumn 8, Issue 1, 2015, Pages 257-264

  Yang, Hua Wei ^a   Lin, Mao Han ^a   Xu, Yuan Zhi ^a   Shang, Guang Wei ^a   Wang, Rao Rao ^a   Chen, Kai ^a  

^a TENTH PEOPLE S HOSPITAL OF TONGJI UNIVERSITY   (China)

Author keywords

Bone marrow mesenchymal stem cells; Hydroxyapatite; Osteogenesis; Strontium; Titanium

Indexed keywords

ALKALINE PHOSPHATASE; BETA1 INTEGRIN; CD11B ANTIGEN; CD45 ANTIGEN; CELL SURFACE MARKER; OSTEOCALCIN; STRONTIUM; STRONTIUM SUBSTITUTED NANO HYDROXYAPATITE COATING; THY 1 ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOCOMPATIBILITY; BIOLOGICAL ACTIVITY; BONE DEVELOPMENT; BONE MARROW DERIVED MESENCHYMAL STEM CELL; BONE REGENERATION; CELL ACTIVITY; CELL ISOLATION; CELL PROLIFERATION; CELL SURFACE; CONTROLLED STUDY; ELECTROCHEMISTRY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FRACTURE HEALING; IMMUNOPHENOTYPING; NEWBORN; NONHUMAN; PROTEIN SECRETION; RAT; ROUGHENED TITANIUM SURFACE; SCANNING ELECTRON MICROSCOPY;

EID: 84923044867     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Wang X and Ye J. Variation of crystal structure of hydroxyapatite in calcium phosphate cement by the substitution of strontium ions. J Mater Sci Mater Med 2008; 19: 1183-1186.
2. Li ZY, Lam WM, Yang C, Xu B, Ni GX, Abbah SA, Cheung KM, Luk KD and Lu WW. Chemical composition, crystal size and lattice structural changes after incorporation of strontium into biomimetic apatite. Biomaterials 2007; 28: 1452-1460.
3. O’Donnell MD, Fredholm Y, de Rouffignac A and Hill RG. Structural analysis of a series of strontium-substituted apatites. Acta Biomater 2008; 4: 1455-1464.
4. Capuccini C, Torricelli P, Sima F, Boanini E, Ristoscu C, Bracci B, Socol G, Fini M, Mihailescu IN and Bigi A. Strontium-substituted hydroxyapatite coatings synthesized by pulsed-laser deposition: in vitro osteoblast and osteoclast response. Acta Biomater 2008; 4: 1885-1893.
5. Capuccini C, Torricelli P, Boanini E, Gazzano M, Giardino R and Bigi A. Interaction of Sr-doped hydroxyapatite nanocrystals with osteoclast and osteoblast-like cells. J Biomed Mater Res A 2009; 89: 594-600.
6. Ni GX, Yao ZP, Huang GT, Liu WG and Lu WW. The effect of strontium incorporation in hydroxyapatite on osteoblasts in vitro. J Mater Sci Mater Med 2011; 22: 961-967.
7. Boanini E, Torricelli P, Fini M and Bigi A. Osteopenic bone cell response to strontium-substituted hydroxyapatite. J Mater Sci Mater Med 2011; 22: 2079-2088.
8. Li Y, Li Q, Zhu S, Luo E, Li J, Feng G, Liao Y and Hu J. The effect of strontium-substituted hydroxyapatite coating on implant fixation in ovariectomized rats. Biomaterials 2010; 31: 9006-9014.
9. Yan J, Zhang YM, Han Y, Zhao YT, Sun JF and Yan H. [Improvement of osseointegration of titanium dental implant surfaces modified with strontium-substituted hydroxyapatite]. Zhong-hua Kou Qiang Yi Xue Za Zhi 2010; 45: 89-93.
10. Yang GL, Song LN, Jiang QH, Wang XX, Zhao SF and He FM. Effect of strontium-substituted nanohydroxyapatite coating of porous implant surfaces on implant osseointegration in a rabbit model. Int J Oral Maxillofac Implants 2012; 27: 1332-1339.
11. Fu DL, Jiang QH, He FM, Yang GL and Liu L. Fluorescence microscopic analysis of bone osseointegration of strontium-substituted hydroxyapatite implants. J Zhejiang Univ Sci B 2012; 13: 364-371.
12. Yang GL, He FM, Hu JA, Wang XX and Zhao SF. Effects of biomimetically and electrochemically deposited nano-hydroxyapatite coatings on osseointegration of porous titanium implants. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 107: 782-789.
13. Verberckmoes SC, De Broe ME and D’Haese PC. Dose-dependent effects of strontium on osteoblast function and mineralization. Kidney Int 2003; 64: 534-543.
14. Bonnelye E, Chabadel A, Saltel F and Jurdic P. Dual effect of strontium ranelate: stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro. Bone 2008; 42: 129-138.
15. Saidak Z and Marie PJ. Strontium signaling: molecular mechanisms and therapeutic implications in osteoporosis. Pharmacol Ther 2012; 136: 216-226.