Regrowth after skeletal muscle atrophy is impaired in aged rats, despite similar responses in signaling pathways

Experimental Gerontology

Volumn 64, Issue , 2015, Pages 17-32

  White, Jena R ^a   Confides, Amy L ^a   Moore Reed, Stephanie ^a   Hoch, Johanna M ^a   Dupont Versteegden, Esther E ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Apoptosis; Autophagy; Hind limb suspension; Inflammation; Protein degradation; Protein synthesis

Indexed keywords

APOPTOSIS INDUCING FACTOR; APOPTOSIS REPRESSOR WITH CASPASE RECRUITMENT DOMAIN; ATROGIN 1; CASPASE 3; CASPASE 8; CASPASE 9; GLYCOGEN SYNTHASE KINASE 3BETA; MESSENGER RNA; MUSCLE RING FINGER 1 PROTEIN; PROTEIN KINASE B; PROTEIN P70; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; BIOLOGICAL MARKER; CASPASE; FBXO32 PROTEIN, RAT; INSULIN; MUSCLE PROTEIN; S6 KINASE; UBIQUITIN PROTEIN LIGASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME ASSAY; GROWTH DISORDER; GROWTH RATE; MALE; MUSCLE ATROPHY; MUSCLE FUNCTION; MUSCLE REGENERATION; NONHUMAN; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SOLEUS MUSCLE; AGING; ANIMAL; BLOOD; BROWN NORWAY RAT; FISCHER 344 RAT; GROWTH, DEVELOPMENT AND AGING; IMMOBILIZATION; METABOLISM; ORGAN SIZE; PATHOLOGY;

ANIMALIA; RATTUS;

AGING; ANIMALS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BIOMARKERS; CASPASES; HINDLIMB SUSPENSION; INSULIN; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; MALE; MUSCLE PROTEINS; MUSCLE, SKELETAL; MUSCULAR ATROPHY; ORGAN SIZE; RATS; RATS, INBRED BN; RATS, INBRED F344; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; SKP CULLIN F-BOX PROTEIN LIGASES;

EID: 84923014269     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2015.02.007     Document Type: Article

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