Revealing hidden clonal complexity in Mycobacterium tuberculosis infection by qualitative and quantitative improvement of sampling

Clinical Microbiology and Infection

Volumn 21, Issue 2, 2015, Pages 147.e1-147.e7

  Perez Lago L ^a,b,c   Palacios, J J ^d   Herranz, M ^a,b,c   Serrano, M J Ruiz ^a,b,c   Bouza, E ^a,b,c,e   Garcia de Viedma D ^a,b,c,e  

^a HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^b HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

^e UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Clonal complexity; Hidden complexity; Improved detection; Sampling schemes; Tuberculosis

Indexed keywords

ALLELE; ARTICLE; BACTERIUM CULTURE; BACTERIUM DETECTION; BACTERIUM ISOLATE; BRONCHIAL ASPIRATION PROCEDURE; CLINICAL ARTICLE; ELECTROPHORESIS; GENETIC SCREENING; GENETIC VARIABILITY; HUMAN; INTERSPERSED REPEAT; LUNG LAVAGE; LUNG TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; RETROSPECTIVE STUDY; SPUTUM ANALYSIS; VARIABLE NUMBER OF TANDEM REPEAT; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHUS; CLASSIFICATION; GENETIC VARIATION; GENETICS; GENOTYPE; MICROBIOLOGY; MOLECULAR TYPING; PROCEDURES; SPECIMEN HANDLING; SPUTUM; TUBERCULOSIS;

MYCOBACTERIUM TUBERCULOSIS;

BRONCHI; BRONCHOALVEOLAR LAVAGE FLUID; GENETIC VARIATION; GENOTYPE; HUMANS; INTERSPERSED REPETITIVE SEQUENCES; MINISATELLITE REPEATS; MOLECULAR TYPING; MYCOBACTERIUM TUBERCULOSIS; RETROSPECTIVE STUDIES; SPECIMEN HANDLING; SPUTUM; TUBERCULOSIS;

EID: 84922981692     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1016/j.cmi.2014.09.015     Document Type: Article

References (21)

1. Al-Hajoj S.A., Akkerman O., Parwati I., al-Gamdi S., Rahim Z., van Soolingen D., et al. Microevolution of Mycobacterium tuberculosis in a tuberculosis patient. JClin Microbiol 2010, 48:3813-3816.
2. Aga R.S., Fair E., Abernethy N.F., Deriemer K., Paz E.A., Kawamura L.M., et al. Microevolution of the direct repeat locus of Mycobacterium tuberculosis in a strain prevalent in san francisco. JClin Microbiol 2006, 44:1558-1560.
3. Navarro Y., Herranz M., Perez-Lago L., Martínez Lirola M., Ruiz-Serrano M.J., et al. Systematic survey of clonal complexity in tuberculosis at a populational level and detailed characterization of the isolates involved. JClin Microbiol 2011, 49:4131-4137.
4. Cave M.D., Yang Z.H., Stefanova R., Fomukong N., Ijaz K., Bates J., et al. Epidemiologic import of tuberculosis cases whose isolates have similar but not identical is6110 restriction fragment length polymorphism patterns. JClin Microbiol 2005, 43:1228-1233.
5. Warren R.M., van der Spuy G.D., Richardson M., Beyers N., Booysen C., Behr M.A., et al. Evolution of the IS6110-based restriction fragment length polymorphism pattern during the transmission of Mycobacterium tuberculosis. JClin Microbiol 2002, 40:1277-1282.
6. Perez-Lago L., Herranz M., Lirola M.M., Bouza E., Garcia de Viedma D. Characterization of microevolution events in Mycobacterium tuberculosis strains involved in recent transmission clusters. JClin Microbiol 2011, 49:3771-3776.
7. Perez-Lago L., Navarro Y., Herranz M., Bouza E., Garcia-de-Viedma D. Differences in gene expression between clonal variants of Mycobacterium tuberculosis emerging as a result of microevolution. Int J Med Microbiol 2013, 303:674-677.
8. McEvoy C.R., Falmer A.A., Gey van Pittius N.C., Victor T.C., van Helden P.D., Warren R.M. The role of IS6110 in the evolution of Mycobacterium tuberculosis. Tuberculosis (Edinb) 2007, 87:393-404.
9. Soto C.Y., Menendez M.C., Perez E., Samper S., Gómez A.B., García M.J., et al. IS6110 mediates increased transcription of the phop virulence gene in a multidrug-resistant clinical isolate responsible for tuberculosis outbreaks. JClin Microbiol 2004, 42:212-219.
10. Tantivitayakul P., Panapruksachat S., Billamas P., Palittapongarnpim P. Variable number of tandem repeat sequences act as regulatory elements in Mycobacterium tuberculosis. Tuberculosis (Edinb) 2010, 90:311-318.
11. Navarro Y., Perez-Lago L., Sislema F., Herranz M., de Juan L., Bouza E., et al. Unmasking subtle differences in the infectivity of microevolved Mycobacterium tuberculosis variants coinfecting the same patient. Int J Med Microbiol 2013, 303:693-696.
12. Perez-Lago L., Comas I., Navarro Y., González-Candelas F., Herranz M., Bouza E., et al. Whole genome sequencing analysis of intrapatient microevolution in Mycobacterium tuberculosis: potential impact on the inference of tuberculosis transmission. JInfect Dis 2014, 209:98-108.
13. Shamputa I.C., Jugheli L., Sadradze N., Willery E., Portaels F., Supply P., et al. Mixed infection and clonal representativeness of a single sputum sample in tuberculosis patients from a penitentiary hospital in Georgia. Respir Res 2006, 7:99.
14. Supply P., Allix C., Lesjean S., Cardoso-Oelemann M., Rüsch-Gerdes S., Willery E., et al. Proposal for standardization of optimized mycobacterial interspersed repetitive unit-variable-number tandem repeat typing of Mycobacterium tuberculosis. JClin Microbiol 2006, 44:4498-4510.
15. Oelemann M.C., Diel R., Vatin V., Haas W., Rüsch-Gerdes S., Locht C., et al. Assessment of an optimized mycobacterial interspersed repetitive- unit-variable-number tandem-repeat typing system combined with spoligotyping for population-based molecular epidemiology studies of tuberculosis. JClin Microbiol 2007, 45:691-697.
16. Alonso M., Herranz M., Martinez Lirola M., Gonzalez-Rivera M., Bouza E., Garcia de Viedma D. Real-time molecular epidemiology of tuberculosis by direct genotyping of smear-positive clinical specimens. JClin Microbiol 2012, 50:1755-1757.
17. Walker T.M., Ip C.L., Harrell R.H., Kapatai G., Dedicoat M.J., Eyre D.W., et al. Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational study. Lancet Infect Dis 2013, 13:137-146.
18. Cohen T., Wilson D., Wallengren K., Samuel E.Y., Murray M. Mixed-strain Mycobacterium tuberculosis infections among patients dying in a hospital in Kwazulu-Natal, South Africa. JClin Microbiol 2011, 49:385-388.
19. Garcia de Viedma D., Marin M., Ruiz Serrano M.J., Alcala L., Bouza E. Polyclonal and compartmentalized infection by Mycobacterium tuberculosis in patients with both respiratory and extrarespiratory involvement. JInfect Dis 2003, 187:695-699.
20. Garcia de Viedma D., Marin M., Andres S., Lorenzo G., Ruiz-Serrano M.J., Bouza E. Complex clonal features in an Mycobacterium tuberculosis infection in a two-year-old child. Pediatr Infect Dis J 2006, 25:457-459.
21. Bansal K., Sinha A.Y., Ghorpade D.S., Togarsimalemath S.K., Patil S.A., Kaveri S.V., et al. Src homology 3-interacting domain of rv1917c of Mycobacterium tuberculosis induces selective maturation of human dendritic cells by regulating pi3k-mapk-nf-kappab signaling and drives th2 immune responses. JBiol Chem 2010, 285:36511-36522.