Multiple facets of poly(ADP-ribose) polymerase-1 in neurological diseases

Neural Regeneration Research

Volumn 10, Issue 1, 2015, Pages 49-51

  Sriram, Chandra Shaker ^a   Jangra, Ashok ^a   Madhana, Rajaram Mohanrao ^a   Gurjar, Satendra Singh ^a   Mohan, Pritam ^b   Bezbaruah, Babul Kumar ^a,c  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

^b Uttar Pradesh Pandit Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwavidyalay Evum Go Anusandhan Sansthan   (India)

^c GAUHATI MEDICAL COLLEGE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INDUCING FACTOR; MP 124; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; POLY (ADENOSINE DIPHOSPHATE RIBOSE); UNCLASSIFIED DRUG;

ADENOSINE DIPHOSPHATE RIBOSYLATION; CEREBROVASCULAR ACCIDENT; DEGENERATIVE DISEASE; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; EPIGENETICS; HUMAN; MITOCHONDRIAL MEMBRANE POTENTIAL; MULTIPLE SCLEROSIS; NEUROLOGIC DISEASE; NONHUMAN; NOTE; TRANSCRIPTION REGULATION; TRAUMATIC BRAIN INJURY;

EID: 84922981069     PISSN: 16735374     EISSN: 18767958     Source Type: Journal    
DOI: 10.4103/1673-5374.150653     Document Type: Note

References (12)

1. Alano CC, Garnier P, Ying W, Higashi Y, Kauppinen TM, Swanson RA (2010) NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death. J Neurosci 30:2967-2978.
2. Berger N, Sims J, Catino D, Berger S (1983) Poly (ADP-ribose) polymerase mediates the suicide response to massive DNA damage: studies in normal and DNA-repair defective cells. Princess Takamatsu Symp 13:219-226.
3. Jangra A, Datusalia AK, Khandwe S, Sharma SS (2013) Amelioration of diabetes-induced neurobehavioral and neurochemical changes by melatonin and nicotinamide: implication of oxidative stress-PARP pathway. Pharmacol Biochem Behav 114:43-51.
4. Krietsch J, Caron MC, Gagné JP, Ethier C, Vignard J, Vincent M, Rouleau M, Hendzel MJ, Poirier GG, Masson JY (2012) PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks. Nucleic Acids Res 40:10287-10301.
5. Lapucci A, Pittelli M, Rapizzi E, Felici R, Moroni F, Chiarugi A (2011) Poly(ADP-ribose) polymerase-1 is a nuclear epigenetic regulator of mitochondrial DNA repair and transcription. Mol Pharmacol 79:932-940.
6. Lodhi N, Kossenkov AV, Tulin AV (2014) Bookmarking promoters in mitotic chromatin: poly (ADP-ribose) polymerase-1 as an epigenetic mark. Nucleic Acids Res 42:7028-7038.
7. Martire S, Fuso A, Rotili D, Tempera I, Giordano C, De Zottis I, Muzi A, Vernole P, Graziani G, Lococo E (2013) PARP-1 modulates amyloid beta peptide-induced neuronal damage. PLoS One 8:e72169.
8. Matsuura S, Egi Y, Yuki S, Horikawa T, Satoh H, Akira T (2011) MP-124, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, ameliorates ischemic brain damage in a non-human primate model Brain Res 1410:122-131.
9. Moroni F, Cozzi A, Chiarugi A, Formentini L, Camaioni E, Pellegrini-Giampietro D, Chen Y, Liang S, Zaleska M, Gonzales C (2012). Long-lasting neuroprotection and neurological improvement in stroke models with new, potent and brain permeable inhibitors of poly (ADP-ribose) polymerase. Br J Pharmacol 165:1487-1500.
10. Rulten SL, Rotheray A, Green RL, Grundy GJ, Moore DA, Gómez-Herreros F, Hafezparast M, Caldecott KW (2014) PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage. Nucleic Acids Res 42:307-314.
11. Sriram CS, Jangra A, Kasalaa ER, Bodduluru LN, Bezbaruah BK (2014) Targeting poly (ADP-ribose) polymerase1 in neurological diseases: a promising trove for new pharmacological interventions to enter clinical translation. Neurochem Int 76:70-81.
12. Stoica BA, Loane DJ, Zhao Z, Kabadi SV, Hanscom M, Byrnes K, Faden AI (2014) PARP-1 inhibition attenuates neuronal loss, microglia activation and neurological deficits after traumatic brain injury. J Neurotrauma 8:758-772.