Gender-specific outcomes of bladder cancer patients: A stage-specific analysis in a contemporary, homogenous radical cystectomy cohort

European Journal of Surgical Oncology

Volumn 41, Issue 3, 2015, Pages 368-377

  Soave, A ^a   Dahlem, R ^a   Hansen, J ^a   Weisbach, L ^a   Minner, S ^a   Engel, O ^a   Kluth, L A ^a   Chun, F K ^a   Shariat, S F ^b   Fisch, M ^a   Rink, M ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Gender; Outcome; Radical cystectomy; Survival; Urinary bladder cancer; Urothelial carcinoma

Indexed keywords

ANTINEOPLASTIC AGENT;

ADULT; AGED; ARTICLE; BLADDER CANCER; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER MORTALITY; CANCER RECURRENCE; CANCER SPECIFIC SURVIVAL; CANCER STAGING; CLINICAL FEATURE; CYSTECTOMY; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; HUMAN; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PREDICTIVE VALUE; PRIORITY JOURNAL; SEX DIFFERENCE; CARCINOMA, TRANSITIONAL CELL; COHORT ANALYSIS; DISEASE FREE SURVIVAL; LYMPH NODE; LYMPH NODE DISSECTION; MIDDLE AGED; PATHOLOGY; PELVIS; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; TREATMENT OUTCOME; TUMOR RECURRENCE; URINARY BLADDER NEOPLASMS;

AGED; CARCINOMA, TRANSITIONAL CELL; COHORT STUDIES; CYSTECTOMY; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; LYMPH NODE EXCISION; LYMPH NODES; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PELVIS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; SEX FACTORS; TREATMENT OUTCOME; URINARY BLADDER NEOPLASMS;

EID: 84922979434     PISSN: 07487983     EISSN: 15322157     Source Type: Journal    
DOI: 10.1016/j.ejso.2014.03.003     Document Type: Article

References (30)

1. R. Siegel, D. Naishadham, and A. Jemal Cancer statistics, 2012 CA Cancer J Clin 62 1 2012 10 29
2. J.A. Witjes, E. Compérat, and N.C. Cowan EAU guidelines on muscle-invasive and metastatic bladder cancer: summary of the 2013 guidelines Eur Urol 65 4 2014 778 792
3. S.F. Shariat, J.P. Sfakianos, M.J. Droller, P.I. Karakiewicz, S. Meryn, and B.H. Bochner The effect of age and gender on bladder cancer: a critical review of the literature BJU Int 105 3 2010 300 308
4. D. Puente, N. Malats, and L. Cecchini Gender-related differences in clinical and pathological characteristics and therapy of bladder cancer Eur Urol 43 1 2003 53 62
5. H. Fajkovic, J. Halpern, and E. Cha Impact of gender on bladder cancer incidence, staging, and prognosis World J Urol 29 4 2011 457 463
6. L. Kluth, H. Fajkovic, and E. Xylinas Female gender is associated with higher risk of disease recurrence in patients with primary T1 high-grade urothelial carcinoma of the bladder World J Urol 31 5 2013 1029 1036
7. A.P. Mitra, E.C. Skinner, A.K. Schuckman, D.I. Quinn, T.B. Dorff, and S. Daneshmand Effect of gender on outcomes following radical cystectomy for urothelial carcinoma of the bladder: a critical analysis of 1,994 patients Urol Oncol - Semin Orig Investig 32 1 2014 52.e1 52.e9
8. B.H. Bochner, M.W. Kattan, K.C. Vora, and International Bladder Cancer Nomogram Consortium Postoperative nomogram predicting risk of recurrence after radical cystectomy for bladder cancer J Clin Oncol 24 24 2006 3967 3972
9. P.I. Karakiewicz, S.F. Shariat, and G.S. Palapattu Nomogram for predicting disease recurrence after radical cystectomy for transitional cell carcinoma of the bladder J Urol 176 4 2006 1354 1356
10. A.J. Vickers, A.M. Cronin, M.W. Kattan International Bladder Cancer Nomogram Consortium Clinical benefits of a multivariate prediction model for bladder cancer: a decision analytic approach Cancer 115 2009 5460 5469
11. W. Otto, M. May, and H.-M. Fritsche Analysis of sex differences in cancer-specific survival and perioperative mortality following radical cystectomy: results of a large German multicenter study of nearly 2500 patients with urothelial carcinoma of the bladder Gend Med 9 6 2012 481 489
12. M. May, C. Stief, and S. Brookman-May Gender-dependent cancer-specific survival following radical cystectomy World J Urol 2012 1 7
13. N.A. Mungan, K.K.H. Aben, and M.P. Schoenberg Gender differences in stage-adjusted bladder cancer survival Urology 55 6 2000 876 880
14. M. Rink, J. Hansen, and E.K. Cha Outcomes and prognostic factors in patients with a single lymph node metastasis at time of radical cystectomy BJU Int 111 1 2013 74 84
15. J.I. Epstein, M.B. Amin, V.R. Reuter, F.K. Mostofi, and T.B.C.C. Committee The World Health Organization/International Society of Urological Pathology consensus classification of urothelial (transitional cell) neoplasms of the urinary bladder Am J Surg Pathol 22 12 1998 1435 1448
16. Y. Lotan, A. Gupta, and S.F. Shariat Lymphovascular invasion is independently associated with overall survival, cause-specific survival, and local and distant recurrence in patients with negative lymph nodes at radical cystectomy J Clin Oncol 23 27 2005 6533 6539
17. G. Novara, R.S. Svatek, and P.I. Karakiewicz Soft tissue surgical margin status is a powerful predictor of outcomes after radical cystectomy: a multicenter study of more than 4,400 patients J Urol 183 6 2010 2165 2170
18. M. Rink, H. Fajkovic, and E.K. Cha Death certificates are valid for the determination of cause of death in patients with upper and lower tract urothelial carcinoma Eur Urol 61 4 2012 854 855
19. B.B. Najari, M. Rink, and P.S. Li Sex disparities in cancer mortality: the risks of being a man in the United States J Urol 189 4 2013 1470 1474 [Epub 2012/12/05]
20. N.A. Mungan, L.A.L.M. Kiemeney, J.A.A.M. van Dijck, H.G. van der Poel, and J.A. Witjes Gender differences in stage distribution of bladder cancer Urology 55 3 2000 368 371
21. L.A. Kluth, M. Rieken, and E. Xylinas Gender-specific differences in clinicopathologic outcomes following radical cystectomy: an international multi-institutional study of more than 8000 patients Eur Urol 2013 10.1016/j.eururo.2013.11.040 [Epub ahead of print]
22. G. Lyratzopoulos, G.A. Abel, S. McPhail, R.D. Neal, and G.P. Rubin Gender inequalities in the promptness of diagnosis of bladder and renal cancer after symptomatic presentation: evidence from secondary analysis of an English primary care audit survey BMJ Open 3 6 2013 e002861
23. F. Kunath, B. Keck, and S. Bertz Is gender becoming relevant in uro-oncological research? A bibliographical analysis World J Urol 2013 1 8
24. G. Gakis, and A. Stenzl Gender-specific differences in muscle-invasive bladder cancer: the concept of sex steroid sensitivity World J Urol 31 5 2013 1059 1064 [Epub 2013/02/12]
25. C. Jeldres, H. Isbarn, and U. Capitanio Gender is an important predictor of cancer-specific survival in patient with transitional cell carcinoma after radical cystectomy J Urol 181 4 2009 635
26. D. Tilki, R.S. Svatek, and P.I. Karakiewicz Characteristics and outcomes of patients with pT4 urothelial carcinoma at radical cystectomy: a retrospective international study of 583 patients J Urol 183 1 2010 87 93
27. D. Tilki, R.S. Svatek, and G. Novara Stage pT0 at radical cystectomy confers improved survival: an international study of 4,430 patients J Urol 184 3 2010 888 894
28. D. Tilki, O. Reich, and R.S. Svatek Characteristics and outcomes of patients with clinical carcinoma in situ only treated with radical cystectomy: an international study of 243 patients J Urol 183 5 2010 1757 1763
29. J.P. Stein, G. Lieskovsky, and R. Cote Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1,054 patients J Clin Oncol 19 3 2001 666 675
30. S.F. Shariat, P.I. Karakiewicz, and G.S. Palapattu Outcomes of radical cystectomy for transitional cell carcinoma of the bladder: a contemporary series from the Bladder Cancer Research Consortium J Urol 176 6 Pt 1 2006 2414 2422