Soft Tissue Surgical Margin Status is a Powerful Predictor of Outcomes After Radical Cystectomy: A Multicenter Study of More Than 4,400 Patients

Journal of Urology

Volumn 183, Issue 6, 2010, Pages 2165-2170

  Novara, Giacomo ^a   Svatek, Robert S ^b   Karakiewicz, Pierre I ^e   Skinner, Eila ⁱ   Ficarra, Vincenzo ^a   Fradet, Yves ^g   Lotan, Yair ^d   Isbarn, Hendrik ^e   Capitanio, Umberto ^e   Bastian, Patrick J ^j,k   Kassouf, Wassim ^f   Fritsche, Hans Martin ^l   Izawa, Jonathan I ^h   Tilki, Derya ^j   Dinney, Colin P ^b   Lerner, Seth P ^c   Schoenberg, Mark ⁿ   Volkmer, Bjoern G ^m   Sagalowsky, Arthur I ^d   Shariat, Shahrokh F ^d  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e UNIVERSITÉ DE MONTRÉAL   (Canada)

^f MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^g UNIVERSITÉ LAVAL   (Canada)

^h UNIVERSITY OF WESTERN ONTARIO   (Canada)

ⁱ UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^j LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^k UNIVERSITY OF BONN   (Germany)

^l UNIVERSITY OF REGENSBURG   (Germany)

^m UNIVERSITY OF ULM   (Germany)

ⁿ JOHNS HOPKINS UNIVERSITY   (United States)

more..

Author keywords

carcinoma; cystectomy; prognosis; survival; transitional cell; urinary bladder neoplasms

Indexed keywords

ANTINEOPLASTIC AGENT;

AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER GRADING; CANCER INVASION; CANCER LOCALIZATION; CANCER MORTALITY; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CYSTECTOMY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; LYMPH VESSEL; MAJOR CLINICAL STUDY; MALE; PELVIS LYMPHADENECTOMY; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; SOFT TISSUE; UROGENITAL TRACT CANCER;

AGED; CARCINOMA, TRANSITIONAL CELL; CYSTECTOMY; FEMALE; HUMANS; MALE; NEOPLASM INVASIVENESS; RETROSPECTIVE STUDIES; SOFT TISSUE NEOPLASMS; URINARY BLADDER NEOPLASMS;

EID: 77951878964     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.juro.2010.02.021     Document Type: Article

References (15)

1. Jemal A., Siegel R., Ward E., et al. Cancer Statistics, 2008. CA Cancer J Clin 59 (2009) 225
2. Ferlay J., Autier P., Boniol M., et al. Estimates of the cancer incidence and mortality in Europe in 2006. Ann Oncol 18 (2007) 581
3. Stenzl A., Cowan N.C., De Santis M., et al. The updated EAU guidelines on muscle-invasive and metastatic bladder cancer. Eur Urol 55 (2009) 815
4. Stein J.P., Lieskovsky G., Cote R., et al. Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1,054 patients. J Clin Oncol 19 (2001) 666
5. Madersbacher S., Hochreiter W., Burkhard F., et al. Radical cystectomy for bladder cancer today-a homogeneous series without neoadjuvant therapy. J Clin Oncol 21 (2003) 690
6. International Bladder Cancer Nomogram Consortium, Bochner B.H., Kattan M.W., et al. Postoperative nomogram predicting risk of recurrence after radical cystectomy for bladder cancer. J Clin Oncol 24 (2006) 3967
7. Karakiewicz P.I., Shariat S.F., Palapattu G.S., et al. Nomogram for predicting disease recurrence after radical cystectomy for transitional cell carcinoma of the bladder. J Urol 176 (2006) 1354
8. Shariat S.F., Karakiewicz P.I., Palapattu G.S., et al. Nomograms provide improved accuracy for predicting survival after radical cystectomy. Clin Cancer Res 12 (2006) 6663
9. Kassouf W., Agarwal P.K., Herr H.W., et al. Lymph node density is superior to TNM nodal status in predicting disease-specific survival after radical cystectomy for bladder cancer: analysis of pooled data from MDACC and MSKCC. J Clin Oncol 26 (2008) 121
10. Dotan Z.A., Kavanagh K., Yossepowitch O., et al. Positive surgical margins in soft tissue following radical cystectomy for bladder cancer and cancer specific survival. J Urol 178 (2007) 2308
11. Hadjizacharia P., Stein J.P., Cai J., et al. The impact of positive soft tissue surgical margins following radical cystectomy for high-grade, invasive bladder cancer. World J Urol 27 (2009) 33
12. Epstein J.I., Amin M.B., Reuter V.R., et al. The World Health Organization/International Society of Urological Pathology consensus classification of urothelial (transitional cell) neoplasms of the urinary bladder. Bladder Consensus Conference Committee. Am J Surg Pathol 22 (1998) 1435
13. Sobin D.H., and Wittekind C.H. TNM Classification of Malignant Tumors. 6th ed. (2002), Wiley-Liss, New York
14. Herr H.W., Faulkner J.R., Grossman H.B., et al. Pathologic evaluation of radical cystectomy specimens: a cooperative group report. Cancer 100 (2004) 2470
15. Herr H., Lee C., Chang S., et al. Standardization of radical cystectomy and pelvic lymph node dissection for bladder cancer: a collaborative group report. J Urol 171 (2004) 1823