Association between obesity and eczema

Dermatitis

Volumn 25, Issue 4, 2014, Pages 172-181

  Silverberg, Jonathan I ^a,b   Simpson, Eric L ^c  

^a NORTHWESTERN UNIVERSITY   (United States)

^b ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ARTICLE; ATOPY; BODY HEIGHT; BODY MASS; BODY WEIGHT; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; ECZEMA; ETHNICITY; FEMALE; HEALTH CARE UTILIZATION; HEALTH SERVICE; HEALTH STATUS; HUMAN; MAJOR CLINICAL STUDY; MALE; OBESITY; OUTCOME ASSESSMENT; PREVALENCE; PRIORITY JOURNAL; QUALITY OF LIFE; SCHOOL CHILD; UNITED STATES; AFRICAN AMERICAN; AMERICAN INDIAN; ETHNOLOGY; HEALTH SURVEY; HISPANIC; INUIT; OCEANIC ANCESTRY GROUP; SEVERITY OF ILLNESS INDEX; STATISTICS AND NUMERICAL DATA; UTILIZATION;

ADOLESCENT; AFRICAN AMERICANS; BODY MASS INDEX; CHILD; ECZEMA; FEMALE; HEALTH SERVICES; HEALTH STATUS; HEALTH SURVEYS; HISPANIC AMERICANS; HUMANS; INDIANS, NORTH AMERICAN; INUITS; MALE; OBESITY; OCEANIC ANCESTRY GROUP; PREVALENCE; QUALITY OF LIFE; SEVERITY OF ILLNESS INDEX; UNITED STATES;

EID: 84922950325     PISSN: 17103568     EISSN: 21625220     Source Type: Journal    
DOI: 10.1097/DER.0000000000000047     Document Type: Article

References (39)

1. Wüthrich B. Clinical aspects, epidemiology, and prognosis of atopic dermatitis. Ann Allergy Asthma Immunol 1999;83(5):464-470.
2. Wüthrich B, Schmid-Grendelmeier P. The atopic eczema/dermatitis syndrome. Epidemiology, natural course, and immunology of the IgEassociated ("extrinsic") and the nonallergic ("intrinsic") AEDS. J Investig Allergol Clin Immunol 2003;13(1):1-5.
3. Kusunoki T, Morimoto T, Nishikomori R, et al. Obesity and the prevalence of allergic diseases in schoolchildren. Pediatr Allergy Immunol 2008; 19(6):527-534.
4. Silverberg JI, Kleiman E, Lev-Tov H, et al. Association between obesity and atopic dermatitis in childhood: A case-control study. J Allergy Clin Immunol 2011;127(5):1180-1186, e1181.
5. Suárez-Varela MM, Alvarez LG, Kogan MD, et al. Diet and prevalence of atopic eczema in 6 to 7-year-old schoolchildren in Spain: ISAAC phase III. J Investig Allergol Clin Immunol 2010;20(6):469-475.
6. Yao TC, Ou LS, Yeh KW, et al. Associations of age, gender, and BMI with prevalence of allergic diseases in children: PATCH study. J Asthma 2011; 48(5):503-510.
7. Hoffman RP. Metabolic syndrome racial differences in adolescents. Curr Diabetes Rev 2009;5(4):259-265.
8. Shaw TE, Currie GP, Koudelka CW, et al. Eczema prevalence in the United States: data from the 2003 National Survey of Children's Health. J Invest Dermatol 2011;131(1):67-73.
9. Akinbami LJ, Ogden CL. Childhood overweight prevalence in the United States: The impact of parent-reported height and weight. Obesity (Silver Spring) 2009;17(8):1574-1580.
10. Silverberg JI, Simpson EL. Association between severe eczema in children and multiple comorbid conditions and increased healthcare utilization. Pediatr Allergy Immunol 2013;24(5):476-486.
11. Skalland BJ, Blumberg SJ. Nonresponse in the National Survey of Children's Health, 2007. Vital Health Stat 2 2012;(156):1-22.
12. Benjamini Y, Hochberg Y. Controlling the false discovery rate: A practical and powerful approach tomultiple testing. J R Stat Soc Series B (Methodological) 1995;57:289-300.
13. Murray CS, Canoy D, Buchan I, et al. Body mass index in young children and allergic disease: gender differences in a longitudinal study. Clin Exp Allergy 2011;41(1):78-85.
14. Silverberg JI, Silverberg NB, Lee-Wong M. Association between atopic dermatitis and obesity in adulthood. Br J Dermatol 2012;166(3):498-504.
15. Vlaski E, Stavric K, Isjanovska R, et al. Overweight hypothesis in asthma and eczema in young adolescents. Allergologia et immunopathologia 2006;34(5):199-205.
16. Spergel JM, Paller AS. Atopic dermatitis and the atopic march. J Allergy Clin Immunol 2003;112(Suppl 6):S118-S127.
17. Al Robaee AA, Shahzad M. Impairment quality of life in families of children with atopic dermatitis. Acta dermatovenerologica Croatica 2010; 18(4):243-247.
18. Haeck IM, ten Berge O, van Velsen SG, et al. Moderate correlation between quality of life and disease activity in adult patients with atopic dermatitis. J Eur Acad Dermatol Venereol 2012;26(2):236-241.
19. Maksimovi N, Jankovi S, Marinkovi J, et al. Health-related quality of life in patients with atopic dermatitis. J Dermatol 2012;39(1):42-47.
20. Monti F, Agostini F, Gobbi F, et al. Quality of life measures in Italian children with atopic dermatitis and their families. Ital J Pediatr 2011;37:59.
21. Torrelo A, Ortiz J, Alomar A, et al. Atopic dermatitis: Impact on quality of life and patients' attitudes toward its management. Eur J Dermatol 2012; 22(1):97-105.
22. DaVeiga SP. Epidemiology of atopic dermatitis: A review. Allergy Asthma Proc 2012;33(3):227-234.
23. Friedlander SL, Larkin EK, Rosen CL, et al. Decreased quality of life associated with obesity in school-aged children. Arch Pediatr Adolesc Med 2003;157(12):1206-1211.
24. Pinhas-Hamiel O, Singer S, Pilpel N, et al. Health-related quality of life among children and adolescents: Associations with obesity. Int J Obes (Lond) 2006;30(2):267-272.
25. Zeller MH, Modi AC. Development and initial validation of an obesityspecific quality-of-life measure for children: Sizing me up. Obesity (Silver Spring) 2009;17(6):1171-1177.
26. Ogden CL, Carroll MD, Kit BK, et al. Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010. JAMA 2012;307(5):483-490.
27. Creely SJ, McTernan PG, Kusminski CM, et al. Lipopolysaccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes. Am J Physiol Endocrinol Metab 2007;292(3): E740-E747.
28. Lin Y, Lee H, Berg AH, et al. The lipopolysaccharide-activated toll-like receptor (TLR)-4 induces synthesis of the closely related receptor TLR-2 in adipocytes. J Biol Chem 2000;275(32):24255-24263.
29. Pietsch J, Batra A, Stroh T, et al. Toll-like receptor expression and response to specific stimulation in adipocytes and preadipocytes: on the role of fat in inflammation. Ann N Y Acad Sci 2006;1072:407-409.
30. Vitseva OI, Tanriverdi K, Tchkonia TT, et al. Inducible toll-like receptor and NF-kappaB regulatory pathway expression in human adipose tissue. Obesity (Silver Spring) 2008;16(5):932-937.
31. Weisberg SP, McCann D, Desai M, et al. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003;112(12): 1796-1808.
32. Rausch ME, Weisberg S, Vardhana P, et al. Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration. Int J Obes (Lond) 2008;32(3):451-463.
33. Kiguchi N, Maeda T, Kobayashi Y, et al. Leptin enhances CC-chemokine ligand expression in cultured murine macrophage. Biochem Biophys Res Commun 2009;384(3):311-315.
34. Lord GM, Matarese G, Howard JK, et al. Leptin inhibits the anti-CD3- driven proliferation of peripheral blood T cells but enhances the production of proinflammatory cytokines. J Leukoc Biol 2002;72(2): 330-338.
35. Martín-Romero C, Santos-Alvarez J, Goberna R, et al. Human leptin enhances activation and proliferation of human circulating T lymphocytes. Cell Immunol 2000;199(1):15-24.
36. Nagel G, Koenig W, Rapp K, et al. Associations of adipokines with asthma, rhinoconjunctivitis, and eczema in German schoolchildren. Pediatr Allergy Immunol 2009;20(1):81-88.
37. Arita Y, Kihara S, Ouchi N, et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Comm 1999;257(1): 79-83.
38. Krämer U, Schäfer T, Behrendt H, et al. The influence of cultural and educational factors on the validity of symptom and diagnosis questions for atopic eczema. Br J Dermatol 1998;139(6):1040-1046.
39. Laughter D, Istvan JA, Tofte SJ, et al. The prevalence of atopic dermatitis in Oregon schoolchildren. J Am Acad Dermatol 2000;43(4):649-655.