메뉴 건너뛰기




Volumn 308, Issue 4, 2015, Pages G313-G324

Phosphorylation dynamics of radixin in hypoxia-induced hepatocyte injury

Author keywords

Bile transporter; Cytoskeleton; Ischemia; Liver; Reperfusion

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; MUTANT PROTEIN; RADIXIN; ABC TRANSPORTER; ABCC2 PROTEIN, RAT; CYTOSKELETON PROTEIN; HIF1A PROTEIN, RAT; MEMBRANE PROTEIN;

EID: 84922932926     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00369.2014     Document Type: Article
Times cited : (8)

References (43)
  • 1
    • 0034897983 scopus 로고    scopus 로고
    • Effect of ischemia-reperfusion on bile canalicular F-actin microfilaments in hepatocytes of human liver allograft: Image analysis by confocal laser scanning microscopy
    • Benkoel L, Dodero F, Hardwigsen J, Campan P, Botta-Fridlund D, Lombardo D, Le Treut YP, Chamlian A. Effect of ischemia-reperfusion on bile canalicular F-actin microfilaments in hepatocytes of human liver allograft: image analysis by confocal laser scanning microscopy. Dig Dis Sci 46: 1663–1667, 2001.
    • (2001) Dig Dis Sci , vol.46 , pp. 1663-1667
    • Benkoel, L.1    Dodero, F.2    Hardwigsen, J.3    Campan, P.4    Botta-Fridlund, D.5    Lombardo, D.6    Le Treut, Y.P.7    Chamlian, A.8
  • 2
    • 0031939306 scopus 로고    scopus 로고
    • Efficient in vitro vectorial transport of a fluorescent conjugated bile acid analogue by polarized hepatic hybrid WIF-B and WIF-B9 cells
    • Bravo P, Bender V, Cassio D. Efficient in vitro vectorial transport of a fluorescent conjugated bile acid analogue by polarized hepatic hybrid WIF-B and WIF-B9 cells. Hepatology 27: 576–583, 1998.
    • (1998) Hepatology , vol.27 , pp. 576-583
    • Bravo, P.1    Bender, V.2    Cassio, D.3
  • 3
    • 0036346708 scopus 로고    scopus 로고
    • ERM proteins and merlin: Integrators at the cell cortex
    • Bretscher A, Edwards K, Fehon RG. ERM proteins and merlin: integrators at the cell cortex. Nat Rev Mol Cell Biol 3: 586–599, 2002.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 586-599
    • Bretscher, A.1    Edwards, K.2    Fehon, R.G.3
  • 4
    • 65149089637 scopus 로고    scopus 로고
    • Autoinhibitory interactions between the PDZ2 and C-terminal domains in the scaffolding protein NHERF1
    • Cheng H, Li J, Fazlieva R, Dai Z, Bu Z, Roder H. Autoinhibitory interactions between the PDZ2 and C-terminal domains in the scaffolding protein NHERF1. Structure 17: 660–669, 2009.
    • (2009) Structure , vol.17 , pp. 660-669
    • Cheng, H.1    Li, J.2    Fazlieva, R.3    Dai, Z.4    Bu, Z.5    Roder, H.6
  • 5
    • 0029895140 scopus 로고    scopus 로고
    • Establishment of hepatic cell polarity in the rat hepatoma-human fibroblast hybrid WIF-B9. A biphasic phenomenon going from a simple epithelial polarized pheno-type to an hepatic polarized one
    • Decaens C, Rodriguez P, Bouchaud C, Cassio D. Establishment of hepatic cell polarity in the rat hepatoma-human fibroblast hybrid WIF-B9. A biphasic phenomenon going from a simple epithelial polarized pheno-type to an hepatic polarized one. J Cell Sci 109: 1623–1635, 1996.
    • (1996) J Cell Sci , vol.109 , pp. 1623-1635
    • Decaens, C.1    Rodriguez, P.2    Bouchaud, C.3    Cassio, D.4
  • 6
    • 33748142546 scopus 로고    scopus 로고
    • Hypoxic liver injury
    • Ebert EC. Hypoxic liver injury. Mayo Clin Proc 81: 1232–1236, 2006.
    • (2006) Mayo Clin Proc , vol.81 , pp. 1232-1236
    • Ebert, E.C.1
  • 8
    • 34247516852 scopus 로고    scopus 로고
    • ERM proteins in epithelial cell organization and functions
    • Fievet B, Louvard D, Arpin M. ERM proteins in epithelial cell organization and functions. Biochim Biophys Acta 1773: 653–660, 2007.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 653-660
    • Fievet, B.1    Louvard, D.2    Arpin, M.3
  • 9
    • 0034631843 scopus 로고    scopus 로고
    • Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane
    • Gautreau A, Louvard D, Arpin M. Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane. J Cell Biol 150: 193–203, 2000.
    • (2000) J Cell Biol , vol.150 , pp. 193-203
    • Gautreau, A.1    Louvard, D.2    Arpin, M.3
  • 10
    • 0016714581 scopus 로고
    • Studies on the pathogenesis of ischemic cell injury. II. Morphological changes of the pars convoluta (P1 and P2) of the proximal tubule of the rat kidney made ischemic in vivo
    • Glaumann B, Glaumann H, Berezesky IK, Trump BF. Studies on the pathogenesis of ischemic cell injury. II. Morphological changes of the pars convoluta (P1 and P2) of the proximal tubule of the rat kidney made ischemic in vivo. Virchows Arch B Cell Pathol Incl Mol Pathol 19: 281–302, 1975.
    • (1975) Virchows Arch B Cell Pathol Incl Mol Pathol , vol.19 , pp. 281-302
    • Glaumann, B.1    Glaumann, H.2    Berezesky, I.K.3    Trump, B.F.4
  • 12
    • 0031695576 scopus 로고    scopus 로고
    • Rho GTPase signaling regulates tight junction assembly and protects tight junctions during ATP depletion
    • Gopalakrishnan S, Raman N, Atkinson SJ, Marrs JA. Rho GTPase signaling regulates tight junction assembly and protects tight junctions during ATP depletion. Am J Physiol Cell Physiol 275: C798-C809, 1998.
    • (1998) Am J Physiol Cell Physiol , vol.275 , pp. C798-C809
    • Gopalakrishnan, S.1    Raman, N.2    Atkinson, S.J.3    Marrs, J.A.4
  • 13
    • 44949158156 scopus 로고    scopus 로고
    • Liver ischemia and ischemia-reperfusion induces and trafficks the multi-specific metal transporter Atp7b to bile duct canaliculi: Possible preferential transport of iron into bile
    • Goss JA, Barshes NR, Karpen SJ, Gao FQ, Wyllie S. Liver ischemia and ischemia-reperfusion induces and trafficks the multi-specific metal transporter Atp7b to bile duct canaliculi: possible preferential transport of iron into bile. Biol Trace Elem Res 122: 26–41, 2008.
    • (2008) Biol Trace Elem Res , vol.122 , pp. 26-41
    • Goss, J.A.1    Barshes, N.R.2    Karpen, S.J.3    Gao, F.Q.4    Wyllie, S.5
  • 14
    • 84911867061 scopus 로고    scopus 로고
    • Alcohol-induced defects in hepatic transcytosis may be explained by impaired dynein function
    • Groebner JL, Fernandez DJ, Tuma DJ, Tuma PL. Alcohol-induced defects in hepatic transcytosis may be explained by impaired dynein function. Mol Cell Biochem 397: 223-233, 2014.
    • (2014) Mol Cell Biochem , vol.397 , pp. 223-233
    • Groebner, J.L.1    Fernandez, D.J.2    Tuma, D.J.3    Tuma, P.L.4
  • 15
    • 84863525767 scopus 로고    scopus 로고
    • Hypoxic hepatitis
    • Henrion J. Hypoxic hepatitis. Liver Int 32: 1039-1052, 2012.
    • (2012) Liver Int , vol.32 , pp. 1039-1052
    • Henrion, J.1
  • 16
    • 78049486376 scopus 로고    scopus 로고
    • Pathogenesis of cholestatic liver disease and therapeutic approaches
    • Hirschfield GM, Heathcote EJ, Gershwin ME. Pathogenesis of cholestatic liver disease and therapeutic approaches. Gastroenterology 139: 1481-1496, 2010.
    • (2010) Gastroenterology , vol.139 , pp. 1481-1496
    • Hirschfield, G.M.1    Heathcote, E.J.2    Gershwin, M.E.3
  • 17
    • 0032576971 scopus 로고    scopus 로고
    • Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand
    • Hu J, Discher DJ, Bishopric NH, Webster KA. Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand. Biochem Biophys Res Com-mun 245: 894-899, 1998.
    • (1998) Biochem Biophys Res Com-Mun , vol.245 , pp. 894-899
    • Hu, J.1    Discher, D.J.2    Bishopric, N.H.3    Webster, K.A.4
  • 19
    • 84908029199 scopus 로고    scopus 로고
    • Distribution dynamics and functional importance of NHERF-1 on regulation of Mrp-2 trafficking in hepatocytes
    • Karvar S, Suda J, Zhu L, Rockey DC. Distribution dynamics and functional importance of NHERF-1 on regulation of Mrp-2 trafficking in hepatocytes. Am J Physiol Cell Physiol 307: C727-C737, 2014.
    • (2014) Am J Physiol Cell Physiol , vol.307 , pp. C727-C737
    • Karvar, S.1    Suda, J.2    Zhu, L.3    Rockey, D.C.4
  • 21
    • 0242690430 scopus 로고    scopus 로고
    • Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis
    • Kojima H, Nies AT, Konig J, Hagmann W, Spring H, Uemura M, Fukui H, Keppler D. Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis. J Hepatol 39: 693-702, 2003.
    • (2003) J Hepatol , vol.39 , pp. 693-702
    • Kojima, H.1    Nies, A.T.2    Konig, J.3    Hagmann, W.4    Spring, H.5    Uemura, M.6    Fukui, H.7    Keppler, D.8
  • 22
    • 38549116688 scopus 로고    scopus 로고
    • Disturbed colocalization of multidrug resistance protein 2 and radixin in human cholestatic liver diseases
    • Kojima H, Sakurai S, Uemura M, Kitamura K, Kanno H, Nakai Y, Fukui H. Disturbed colocalization of multidrug resistance protein 2 and radixin in human cholestatic liver diseases. J Gastroenterol Hepatol 23: e120-e128, 2008.
    • (2008) J Gastroenterol Hepatol , vol.23 , pp. e120-e128
    • Kojima, H.1    Sakurai, S.2    Uemura, M.3    Kitamura, K.4    Kanno, H.5    Nakai, Y.6    Fukui, H.7
  • 24
    • 0031816872 scopus 로고    scopus 로고
    • The early region 4 orf4 protein of human adenovirus type 5 induces p53-independent cell death by apoptosis
    • Marcellus RC, Lavoie JN, Boivin D, Shore GC, Ketner G, Branton PE. The early region 4 orf4 protein of human adenovirus type 5 induces p53-independent cell death by apoptosis. J Virol 72: 7144-7153, 1998.
    • (1998) J Virol , vol.72 , pp. 7144-7153
    • Marcellus, R.C.1    Lavoie, J.N.2    Boivin, D.3    Shore, G.C.4    Ketner, G.5    Branton, P.E.6
  • 25
    • 0032498528 scopus 로고    scopus 로고
    • Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association
    • Matsui T, Maeda M, Doi Y, Yonemura S, Amano M, Kaibuchi K, Tsukita S, Tsukita S. Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association. J Cell Biol 140: 647-657, 1998.
    • (1998) J Cell Biol , vol.140 , pp. 647-657
    • Matsui, T.1    Maeda, M.2    Doi, Y.3    Yonemura, S.4    Amano, M.5    Kaibuchi, K.6    Tsukita, S.7    Tsukita, S.8
  • 26
    • 0025861527 scopus 로고
    • Dissociation and redistribution of Na+,K(+)-ATPase from its surface membrane actin cytoskeletal complex during cellular ATP depletion
    • Molitoris BA, Geerdes A, McIntosh JR. Dissociation and redistribution of Na+,K(+)-ATPase from its surface membrane actin cytoskeletal complex during cellular ATP depletion. J Clin Invest 88: 462–469, 1991.
    • (1991) J Clin Invest , vol.88 , pp. 462-469
    • Molitoris, B.A.1    Geerdes, A.2    McIntosh, J.R.3
  • 27
    • 84856390541 scopus 로고    scopus 로고
    • Hypoxia and hypoxia inducible factors: Diverse roles in liver diseases
    • Nath B, Szabo G. Hypoxia and hypoxia inducible factors: diverse roles in liver diseases. Hepatology 55: 622-633, 2012.
    • (2012) Hepatology , vol.55 , pp. 622-633
    • Nath, B.1    Szabo, G.2
  • 28
    • 34247205380 scopus 로고    scopus 로고
    • Ischemic preconditioning and intermittent ischemia preserve bile flow in a rat model of ischemia/reperfusion injury
    • Nieuwenhuijs VB, de Bruijn MT, Schiesser M, Morphett A, Padbury RT, Barritt GJ. Ischemic preconditioning and intermittent ischemia preserve bile flow in a rat model of ischemia/reperfusion injury. Dig Dis Sci 52: 3029-3037, 2007.
    • (2007) Dig Dis Sci , vol.52 , pp. 3029-3037
    • Nieuwenhuijs, V.B.1    De Bruijn, M.T.2    Schiesser, M.3    Morphett, A.4    Padbury, R.T.5    Barritt, G.J.6
  • 29
    • 0030608877 scopus 로고    scopus 로고
    • Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family
    • Reczek D, Berryman M, Bretscher A. Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family. J Cell Biol 139: 169-179, 1997.
    • (1997) J Cell Biol , vol.139 , pp. 169-179
    • Reczek, D.1    Berryman, M.2    Bretscher, A.3
  • 30
    • 0026478699 scopus 로고
    • 5'Nucleotidase is sorted to the apical domain of hepatocytes via an indirect route
    • Schell MJ, Maurice M, Stieger B, Hubbard AL. 5'Nucleotidase is sorted to the apical domain of hepatocytes via an indirect route. J Cell Biol 119: 1173-1182, 1992.
    • (1992) J Cell Biol , vol.119 , pp. 1173-1182
    • Schell, M.J.1    Maurice, M.2    Stieger, B.3    Hubbard, A.L.4
  • 31
    • 0028230752 scopus 로고
    • An improved polarized rat hepatoma hybrid cell line. Generation and comparison with its hepatoma relatives and hepatocytes in vivo
    • Shanks MR, Cassio D, Lecoq O, Hubbard AL. An improved polarized rat hepatoma hybrid cell line. Generation and comparison with its hepatoma relatives and hepatocytes in vivo. J Cell Sci 107: 813-825, 1994.
    • (1994) J Cell Sci , vol.107 , pp. 813-825
    • Shanks, M.R.1    Cassio, D.2    Lecoq, O.3    Hubbard, A.L.4
  • 32
    • 79952132584 scopus 로고    scopus 로고
    • Phosphorylation of radixin regulates cell polarity and Mrp-2 distribution in hepatocytes
    • Suda J, Zhu L, Karvar S. Phosphorylation of radixin regulates cell polarity and Mrp-2 distribution in hepatocytes. Am J Physiol Cell Physiol 300: C416-C424, 2011.
    • (2011) Am J Physiol Cell Physiol , vol.300 , pp. C416-C424
    • Suda, J.1    Zhu, L.2    Karvar, S.3
  • 33
    • 0034703069 scopus 로고    scopus 로고
    • E3KARP mediates the association of ezrin and protein kinase A with the cystic fibrosis transmembrane conductance regulator in airway cells
    • Sun F, Hug MJ, Lewarchik CM, Yun CH, Bradbury NA, Frizzell RA. E3KARP mediates the association of ezrin and protein kinase A with the cystic fibrosis transmembrane conductance regulator in airway cells. J Biol Chem 275: 29539–29546, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 29539-29546
    • Sun, F.1    Hug, M.J.2    Lewarchik, C.M.3    Yun, C.H.4    Bradbury, N.A.5    Frizzell, R.A.6
  • 34
    • 36949012546 scopus 로고    scopus 로고
    • Ischemia-reperfusion of rat livers decreases liver and increases kidney multidrug resistance associated protein 2 (Mrp2)
    • Tanaka Y, Chen C, Maher JM, Klaassen CD. Ischemia-reperfusion of rat livers decreases liver and increases kidney multidrug resistance associated protein 2 (Mrp2). Toxicol Sci 101: 171–178, 2008.
    • (2008) Toxicol Sci , vol.101 , pp. 171-178
    • Tanaka, Y.1    Chen, C.2    Maher, J.M.3    Klaassen, C.D.4
  • 35
    • 84905912468 scopus 로고    scopus 로고
    • Moesin functionality in hypothermic liver preservation injury
    • Tian T, Lindell SL, Kowalski C, Mangino MJ. Moesin functionality in hypothermic liver preservation injury. Cryobiology 69: 34–40, 2014.
    • (2014) Cryobiology , vol.69 , pp. 34-40
    • Tian, T.1    Lindell, S.L.2    Kowalski, C.3    Mangino, M.J.4
  • 36
    • 84861679564 scopus 로고    scopus 로고
    • Ezrin functionality and hypothermic preservation injury in LLC-PK1 cells
    • Tian T, Lindell SL, Lam M, Mangino MJ. Ezrin functionality and hypothermic preservation injury in LLC-PK1 cells. Cryobiology 65: 60–67, 2012.
    • (2012) Cryobiology , vol.65 , pp. 60-67
    • Tian, T.1    Lindell, S.L.2    Lam, M.3    Mangino, M.J.4
  • 37
    • 0019868584 scopus 로고
    • Mechanism of proximal tubule brush border loss and regeneration following mild renal ischemia
    • Venkatachalam MA, Jones DB, Rennke HG, Sandstrom D, Patel Y. Mechanism of proximal tubule brush border loss and regeneration following mild renal ischemia. Lab Invest 45: 355–365, 1981.
    • (1981) Lab Invest , vol.45 , pp. 355-365
    • Venkatachalam, M.A.1    Jones, D.B.2    Rennke, H.G.3    Sandstrom, D.4    Patel, Y.5
  • 38
    • 33748758162 scopus 로고    scopus 로고
    • Transporters on demand: Intracel-lular reservoirs and cycling of bile canalicular ABC transporters
    • Wakabayashi Y, Kipp H, Arias IM. Transporters on demand: intracel-lular reservoirs and cycling of bile canalicular ABC transporters. J Biol Chem 281: 27669–27673, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 27669-27673
    • Wakabayashi, Y.1    Kipp, H.2    Arias, I.M.3
  • 39
    • 1842427904 scopus 로고    scopus 로고
    • The maintenance and generation of membrane polarity in hepatocytes
    • Wang L, Boyer JL. The maintenance and generation of membrane polarity in hepatocytes. Hepatology 39: 892–899, 2004.
    • (2004) Hepatology , vol.39 , pp. 892-899
    • Wang, L.1    Boyer, J.L.2
  • 40
    • 33748101755 scopus 로고    scopus 로고
    • Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes
    • Wang W, Soroka CJ, Mennone A, Rahner C, Harry K, Pypaert M, Boyer JL. Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. Gastroenterology 131: 878–884, 2006.
    • (2006) Gastroenterology , vol.131 , pp. 878-884
    • Wang, W.1    Soroka, C.J.2    Mennone, A.3    Rahner, C.4    Harry, K.5    Pypaert, M.6    Boyer, J.L.7
  • 41
    • 0035918213 scopus 로고    scopus 로고
    • Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, and p300/CBP
    • Yamashita K, Discher DJ, Hu J, Bishopric NH, Webster KA. Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, and p300/CBP. J Biol Chem 276: 12645–12653, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 12645-12653
    • Yamashita, K.1    Discher, D.J.2    Hu, J.3    Bishopric, N.H.4    Webster, K.A.5
  • 42
    • 77949349287 scopus 로고    scopus 로고
    • Ethanol-induced expression of ET-1 and ET-BR in liver sinusoidal endothelial cells and human endothe-lial cells involves hypoxia-inducible factor-1alpha and microrNA-199
    • Yeligar S, Tsukamoto H, Kalra VK. Ethanol-induced expression of ET-1 and ET-BR in liver sinusoidal endothelial cells and human endothe-lial cells involves hypoxia-inducible factor-1alpha and microrNA-199. J Immunol 183: 5232–5243, 2009.
    • (2009) J Immunol , vol.183 , pp. 5232-5243
    • Yeligar, S.1    Tsukamoto, H.2    Kalra, V.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.