Efficiency of short, small-diameter columns for reversed-phase liquid chromatography under practical operating conditions

Journal of Chromatography A

Volumn 1383, Issue , 2015, Pages 47-57

  Ma, Yan ^a   Chassy, Alexander W ^a   Miyazaki, Shota ^b   Motokawa, Masanori ^b   Morisato, Kei ^b,c   Uzu, Hideyuki ^b   Ohira, Masayoshi ^b   Furuno, Masahiro ^b   Nakanishi, Kazuki ^c   Minakuchi, Hiroyoshi ^d   Mriziq, Khaled ^e   Farkas, Tivadar ^f   Fiehn, Oliver ^a,g   Tanaka, Nobuo ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b GL SCIENCES INC   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d Kyoto Monotech Ltd   (Japan)

^e MDS SCIEX   (Canada)

^f PHENOMENEX INC   (United States)

^g UNIVERSITY OF JEDDAH   (Saudi Arabia)

Author keywords

1mm I.D. column; Column efficiency; Core shell particles; Extra column effect; Monolithic silica; Weak wash solvent

Indexed keywords

EFFICIENCY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHANOL; ORGANIC SOLVENTS; SHELLS (STRUCTURES); SILICA;

COLUMN EFFICIENCY; COMPRESSION EFFECTS; CORE SHELL PARTICLES; EXTRA-COLUMN EFFECT; MONOLITHIC SILICA; PRACTICAL OPERATING CONDITIONS; REVERSED PHASE LIQUID-CHROMATOGRAPHY; ULTRAHIGH-PRESSURE LIQUID CHROMATOGRAPHIES;

COLUMN CHROMATOGRAPHY;

METHANOL; SILICON DIOXIDE; WATER; ACETONITRILE; ACETONITRILE DERIVATIVE;

ANALYTICAL EQUIPMENT; ARTICLE; CELL SIZE; COMMERCIAL PHENOMENA; ELUTION; FLOW RATE; PARTICLE SIZE; POROSITY; PROCESS OPTIMIZATION; QUALITY CONTROL; REVERSED PHASE LIQUID CHROMATOGRAPHY; SMALL SIZE COLUMN; SOLVENT EFFECT; SYSTEM ANALYSIS; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET DETECTOR; CHEMISTRY; DEVICES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PERMEABILITY;

ACETONITRILES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; METHANOL; PARTICLE SIZE; PERMEABILITY; POROSITY; SILICON DIOXIDE; WATER;

EID: 84922926766     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2015.01.014     Document Type: Article

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