Effect of column dimension on observed column efficiency in very high pressure liquid chromatography

Journal of Chromatography A

Volumn 1261, Issue , 2012, Pages 113-120

  Wu, Naijun ^a   Bradley, Ashley C ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NORTH CAROLINA A AND T STATE UNIVERSITY   (United States)

Author keywords

Band broadening; Column dimension; Extra column volume; Sub 2 m particles; Ultra high pressure liquid chromatography; UPLC

Indexed keywords

BAND-BROADENING; COLUMN DIMENSIONS; EXTRA-COLUMN VOLUME; ULTRAHIGH PRESSURE; UPLC;

EFFICIENCY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; OFFSHORE PIPELINES; TUBING;

CHROMATOGRAPHY;

ACETONITRILE; BENZOPHENONE; PROPIOPHENONE; WATER;

ARTICLE; CONTROLLED STUDY; EQUIPMENT DESIGN; FLOW RATE; MATHEMATICAL COMPUTING; PARTICLE SIZE; PHYSICAL PHASE; PRIORITY JOURNAL; REACTION TIME; SEPARATION TECHNIQUE; THEORETICAL STUDY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VELOCITY;

ACETONITRILES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; KETONES; MODELS, CHEMICAL; PARTICLE SIZE; WATER;

EID: 84866926481     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2012.05.054     Document Type: Article

References (39)

1. MacNair J.E., Lewis K.C., Jorgenson J.W. Anal. Chem. 1997, 69:983.
2. MacNair J.E., Patel K.D., Jorgenson J.W. Anal. Chem. 1999, 71:700.
3. Lippert A.J., Xin B., Wu N., Lee M.L. J. Microcolumn Sep. 1999, 11:631.
4. Wu N., Collins D.C., Lippert A.J., Xiang Y., Lee M.L. J. Microcolumn Sep. 2000, 12:462.
5. Wu N., Lippert A.J., Lee M.L. J. Chromatogr. A 2001, 911:1.
6. Xiang Y., Yan B., Mcneff C.V., Carr P.W., Lee M.L. J. Chromatogr. A 2003, 983:83.
7. Xiang Y., Maynes D.R., Lee M.L. J. Chromatogr. A 2003, 991:189.
8. Xiang Y., Liu Y., Stanley D.S., Plistil A., Brisbin M.P., Lee M.L. Anal. Chem. 2006, 78:858.
9. Wu N., Clausen A. J. Sep. Sci. 2007, 30:1167.
10. Mazzeo J.R., Neue U.D., Kele M., Plumb R.S. Anal. Chem. 2005, 77:460A.
11. Gritti F., Guiochon G. J. Chromatogr. A 2012, 1228:2.
12. Halasz I., Endele R., Asshauer J. J. Chromatogr. 1975, 112:37.
13. Lin H.-J., Horvath Cs. Chem. Eng. Sci. 1981, 36:47.
14. Gritti F., Guiochon G. J. Chromatogr. A 2007, 1138:141.
15. Gritti F., Martin M., Guiochon G. Anal. Chem. 2009, 81:3365.
16. Poppe H., Kraak J.C., Huber J.F.K., van den Berg J.H.M. Chromatographia 1981, 14:515.
17. Colon L.A., Cintron J.M., Anspach J.A., Fermier A.M., Swinney K.A. Analyst 2004, 129:503.
18. Welch C.J., Wu N., Biba M., Hartman R., Brkovic T., Gong X., Helmy R., Schafer W., Cuff J.J., Pirzada Z., Zhou L. Trends Anal. Chem. 2010, 77:667.
19. Chen S., Kord A. J. Chromatogr. A 2009, 1216:6204.
20. Yeung E.S. Microcolumn Separations 1985, vol. 30:117. Elsevier, Amsterdam, (Journal of Chromatography Library).
21. Krejci M. Trace Analysis with Microcolumn Liquid Chromatography 1992, Marcel Dekker, New York, p. 35.
22. Kirkland J.J., Yau W.W., Stoklosa H.J., Dilks C.H. J. Chromatogr. Sci. 1977, 15:303.
23. Grittia F., Felinger A., Guiochon G. J. Chromatogr. A 2006, 1136:57.
24. Prüß A., Kempter C., Gysler J., Jira T. J. Chromatogr. A 2003, 1016:129.
25. Fountain K.J., Neue U.D., Grumbach E.S., Diehl D.M. J. Chromatogr. A 2009, 1216:5979.
26. Usher K.M., Simmons C.R., Dorsey J.G. J. Chromatogr. A 2008, 1200:122.
27. Cabooter D., Billen J., Terryn H., Lynen F., Sandra P., Desmet G. J. Chromatogr. A 2008, 1204:1.
28. Cabooter D., de Villiers A., Clicq D., Szucs R., Sandra P., Desmet G. J. Chromatogr. A 2007, 1147:183.
29. Lestremau F., Wu D., Szücs R. J. Chromatogr. A 2010, 1217:4925.
30. Alexander A.J., Waeghe T.J., Himes K.W., Tomasella F.P., Hooker T.F. J. Chromatogr. A 2011, 1218:5456.
31. Van Deemter J.J., Zuiderweg F.J., Kinkenberg A. Chem. Eng. Sci. 1956, 5:271.
32. Snyder L.R., Kirkland J.J. Introduction to Modern Liquid Chromatography 1979, John Wiley, New York.
33. Yan B., Carr P.W. Anal. Chem. 2000, 72:1253.
34. Guillarme D., Nguyen D.T.-T., Rudaz S., Veuthey J.-L. Eur. J. Pharm. Biopharm. 2007, 66:475.
35. Li J., Carr P.W. Anal. Chem. 1997, 69:2530.
36. Atwood J.G., Goldstein J. J. Phys. Chem. 1984, 88:1875.
37. McCalley D.V. J. Chromatogr. A 2010, 1217:4561.
38. Golay M.J.E., Atwood J.G. J. Chromatogr. 1979, 186:353.
39. Atwood J.G., Golay M.J.E. J. Chromatogr. 1981, 218:97.