Angiogenic cytokine expression profiles in plasma and synovial fluid of primary knee osteoarthritis

International Orthopaedics

Volumn 38, Issue 9, 2014, Pages 1885-1892

  Mabey, Thomas ^a   Honsawek, Sittisak ^a   Saetan, Natthaphon ^a   Poovorawan, Yong ^a   Tanavalee, Aree ^a   Yuktanandana, Pongsak ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Angiogenesis; Cytokine; Osteoarthritis; Plasma; Synovial fluid

Indexed keywords

ANGIOPOIETIN 2; CD31 ANTIGEN; CYTOKINE; FOLLISTATIN; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 8; LEPTIN; PLATELET DERIVED GROWTH FACTOR BB; SCATTER FACTOR; VASCULOTROPIN; ANGIOGENIC PROTEIN; BIOLOGICAL MARKER; VASCULOTROPIN A;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; FEMALE; HUMAN; IMMUNOASSAY; KNEE OSTEOARTHRITIS; MALE; PLASMA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SYNOVIAL FLUID; BLOOD; CASE CONTROL STUDY; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MIDDLE AGED; SEVERITY OF ILLNESS INDEX; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ANGIOGENIC PROTEINS; ANGIOPOIETIN-2; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CYTOKINES; FEMALE; FOLLISTATIN; GENE EXPRESSION PROFILING; HUMANS; MALE; MIDDLE AGED; OSTEOARTHRITIS, KNEE; SEVERITY OF ILLNESS INDEX; SYNOVIAL FLUID; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84922834242     PISSN: 03412695     EISSN: 14325195     Source Type: Journal    
DOI: 10.1007/s00264-014-2406-y     Document Type: Article

References (39)

1. Pelletier JP, Martel-Pelletier J, Abramson SB (2001) Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets. Arthritis Rheum 44:1237-1247
2. Walsh DA, McWilliams DF, Turley MJ, Dixon MR, Franses RE, Mapp PI, Wilson D (2010) Angiogenesis and nerve growth factor at the osteochondral junction in rheumatoid arthritis and osteoarthritis. Rheumatology (Oxford) 49:1852-1861
3. Mapp PI, Walsh DA (2012) Mechanisms and targets of angiogenesis and nerve growth in osteoarthritis. Nat Rev Rheumatol 8:390-398
4. Cackowski FC, Anderson JL, Patrene KD, Choksi RJ, Shapiro SD, Windle JJ, Blair HC, Roodman GD (2010) Osteoclasts are important for bone angiogenesis. Blood 115:140-149
5. Kellgren JH, Lawrence JS (1957) Radiological assessment of osteo-arthrosis. Ann Rheum Dis 16:494-502
6. Haywood L, McWilliams DF, Pearson CI, Gill SE, Ganesan A, Wilson D, Walsh DA (2003) Inflammation and angiogenesis in osteoarthritis. Arthritis Rheum 48:2173-2177
7. Suri S, Gill SE, Massena de Camin S, Wilson D, McWilliams DF, Walsh DA (2007) Neurovascular invasion at the osteochondral junction and in osteophytes in osteoarthritis. Ann Rheum Dis 66:1423-1428
8. Rubenhagen R, Schuttrumpf JP, Sturmer KM, Frosch KH (2012) Interleukin-7 levels in synovial fluid increase with age and mmp-1 levels decrease with progression of osteoarthritis. Acta Orthop 83: 59-64
9. Orita S, Koshi T, Mitsuka T, Miyagi M, Inoue G, Arai G, Ishikawa T, Hanaoka E, Yamashita K, Yamashita M, Eguchi Y, Toyone T, Takahashi K, Ohtori S (2011) Associations between proinflammatory cytokines in the synovial fluid and radiographic grading and pain-related scores in 47 consecutive patients with osteoarthritis of the knee. BMC Musculoskelet Disord 12:144
10. Hoff P, Buttgereit F, Burmester GR, Jakstadt M, Gaber T, Andreas K, Matziolis G, Perka C, Röhner E (2013) Osteoarthritis synovial fluid activates pro-inflammatory cytokines in primary human chondrocytes. Int Orthop 37:145-151
11. Melinte R, Jung I, Georgescu L, Gurzu S (2012) Vegf and cd31 expression in arthritic synovium and cartilage of human knee joints. Rom J Morphol Embryol 53:911-915
12. Enomoto H, Inoki I, Komiya K, Shiomi T, Ikeda E, Obata K, Matsumoto H, Toyama Y, Okada Y (2003) Vascular endothelial growth factor isoforms and their receptors are expressed in human osteoarthritic cartilage. Am J Pathol 162:171-181
13. Honorati MC, Cattini L, Facchini A (2004) Il-17, il-1beta and tnfalpha stimulate vegf production by dedifferentiated chondrocytes. Osteoarthr Cartil 12:683-691
14. Das RH, van Osch GJ, Kreukniet M, Oostra J, Weinans H, Jahr H (2010) Effects of individual control of ph and hypoxia in chondrocyte culture. J Orthop Res 28:537-545
15. Saetan N, Honsawek S, Tanavalee A, Yuktanandana P, Meknavin S, Ngarmukos S, Tanpowpong T, Parkpian V (2014) Relationship of plasma and synovial fluid vascular endothelial growth factor with radiographic severity in primary knee osteoarthritis. Int Orthop 38:1099-1104
16. Ramirez J, Ruiz-Esquide V, Pomes I, Celis R, Cuervo A, Hernandez MV, Pomés J, Pablos JL, Sanmartí R, Cañete JD (2014) Patients with rheumatoid arthritis in clinical remission and ultrasound-defined active synovitis exhibit higher disease activity and increased serum levels of angiogenic biomarkers. Arthritis Res Ther 16:R5
17. Gao W, Sweeney C, Walsh C, Rooney P, McCormick J, Veale DJ, Fearon U (2013) Notch signalling pathways mediate synovial angiogenesis in response to vascular endothelial growth factor and angiopoietin 2. Ann Rheum Dis 72:1080-1088
18. Yuan HT, Khankin EV, Karumanchi SA, Parikh SM (2009) Angiopoietin 2 is a partial agonist/antagonist of tie2 signaling in the endothelium. Mol Cell Biol 29:2011-2022
19. Singh H, Milner CS, Aguilar Hernandez MM, Patel N, Brindle NP (2009) Vascular endothelial growth factor activates the tie family of receptor tyrosine kinases. Cell Signal 21:1346-1350
20. Uchida T, Nakashima M, Hirota Y, Miyazaki Y, Tsukazaki T, Shindo H (2000) Immunohistochemical localisation of protein tyrosine kinase receptors tie-1 and tie-2 in synovial tissue of rheumatoid arthritis: correlation with angiogenesis and synovial proliferation. Ann Rheum Dis 59:607-614
21. Zhang L, Yang N, Park JW, Katsaros D, Fracchioli S, Cao G, O'Brien-Jenkins A, Randall TC, Rubin SC, Coukos G (2003) Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer. Cancer Res 63:3403-3412
22. Oh H, Takagi H, Suzuma K, Otani A, Matsumura M, Honda Y (1999) Hypoxia and vascular endothelial growth factor selectively up-regulate angiopoietin-2 in bovine microvascular endothelial cells. J Biol Chem 274:15732-15739
23. Iemura S, Yamamoto TS, Takagi C, Uchiyama H, Natsume T, Shimasaki S, Sugino H, Ueno N (1998) Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early xenopus embryo. Proc Natl Acad Sci USA 95:9337-9342
24. Bragdon B, Moseychuk O, Saldanha S, King D, Julian J, Nohe A (2011) Bone morphogenetic proteins: a critical review. Cell Signal 23:609-620
25. Song B, Estrada KD, Lyons KM (2009) Smad signaling in skeletal development and regeneration. Cytokine Growth Factor Rev 20:379-388
26. Tardif G, Hum D, Pelletier JP, Boileau C, Ranger P, Martel-Pelletier J (2004) Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts. Arthritis Rheum 50:2521-2530
27. El-Gendi SS, Moniem AE, Tawfik NM, Ashmawy MM, Mohammed OA, Mostafa AK, Zakhari MM, Herdan OM (2010) Value of serum and synovial fluid activin a and inhibin a in some rheumatic diseases. Int J Rheum Dis 13:273-279
28. Alexander S, Watt F, Sawaji Y, Hermansson M, Saklatvala J (2007) Activin a is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and nfkappab. Arthritis Rheum 56:3715-3725
29. Lubbeke A, Finckh A, Puskas GJ, Suva D, Ladermann A, Bas S, Fritschy D, Gabay C, Hoffmeyer P (2013) Do synovial leptin levels correlate with pain in end stage arthritis? Int Orthop 37:2071-2079
30. Staikos C, Ververidis A, Drosos G, Manolopoulos VG, Verettas DA, Tavridou A (2013) The association of adipokine levels in plasma and synovial fluid with the severity of knee osteoarthritis. Rheumatology (Oxford) 52:1077-1083
31. Karvonen-Gutierrez CA, Harlow SD, Mancuso P, Jacobson J, Mendes de Leon CF, Nan B (2013) Association of leptin levels with radiographic knee osteoarthritis among a cohort of midlife women. Arthritis Care Res (Hoboken) 65:936-944
32. Vuolteenaho K, Koskinen A, Kukkonen M, Nieminen R, Paivarinta U, Moilanen T, Moilanen E (2009) Leptin enhances synthesis of proinflammatory mediators in human osteoarthritic cartilage-mediator role of no in leptin-induced pge2, il-6, and il-8 production.Mediat Inflamm 2009:345838
33. van der Heide HJ, van der Kraan PM, Rijnberg WJ, Buma P, Schreurs BW (2010) Elevated levels of numerous cytokines in drainage fluid after primary total hip arthroplasty. Int Orthop 34:1099-1102
34. Abe H, Sakai T, Ando W, Takao M, Nishii T, Nakamura N, Hamasaki T, Yoshikawa H, Sugano N (2014) Synovial joint fluid cytokine levels in hip disease. Rheumatology 53:165-172
35. Kaneko S, Satoh T, Chiba J, Ju C, Inoue K, Kagawa J (2000) Interleukin-6 and interleukin-8 levels in serum and synovial fluid of patients with osteoarthritis. Cytokines Cell Mol Ther 6:71-79
36. Bon JM, Zhang Y, Duncan SR, Pilewski JM, Zaldonis D, Zeevi A, McCurry KR, Greenspan SL, Sciurba FC (2010) Plasma inflammatory mediators associated with bone metabolism in copd. COPD 7:186-191
37. Huebner JL, Kraus VB (2006) Assessment of the utility of biomarkers of osteoarthritis in the guinea. Osteoarthr Cartil 14:923-930
38. Huebner JL, Seifer DR, Kraus VB (2007) A longitudinal analysis of serum cytokines in the Hartley guinea pig model of osteoarthritis. Osteoarthr Cartil 15:354-356
39. Korkusuz P, Dagdeviren A, Eksioglu F, Ors U (2005) Immunohistological analysis of normal and osteoarthritic human synovial tissue. Bull Hosp Jt Dis 63:63-69