Nebivolol for improving endothelial dysfunction, pulmonary vascular remodeling, and right heart function in pulmonary hypertension

Journal of the American College of Cardiology

Volumn 65, Issue 7, 2015, Pages 668-680

  Perros, Frédéric ^a,b,c   Ranchoux, Benoît ^a,b,c   Izikki, Mohamed ^d   Bentebbal, Sana ^d   Happé, Chris ^e   Antigny, Fabrice ^a,b,c   Jourdon, Philippe ^a,b,c   Dorfmüller, Peter ^a,b,c   Lecerf, Florence ^a,b,c   Fadel, Elie ^c   Simonneau, Gerald ^a,b,c   Humbert, Marc ^a,b,c   Bogaard, Harm Jan ^e   Eddahibi, Saadia ^d  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b BICÊTRE HOSPITAL   (France)

^c CENTRE CHIRURGICAL MARIE LANNELONGUE   (France)

^d UNIV MONTPELLIER   (France)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

endothelial dysfunction; inflammation; nebivolol; pulmonary hypertension; blocker

Indexed keywords

ENDOTHELIN 1; FIBROBLAST GROWTH FACTOR 2; INTERLEUKIN 6; METOPROLOL; MONOCROTALINE; MONOCYTE CHEMOTACTIC PROTEIN 1; NEBIVOLOL; NITRIC OXIDE; BENZOPYRAN DERIVATIVE; BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ETHANOLAMINE DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTERY DILATATION; ARTICLE; CELL PROLIFERATION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; HEART RIGHT VENTRICLE HYPERTROPHY; HEART RIGHT VENTRICLE PRESSURE; HUMAN; HUMAN CELL; LUNG ARTERY PRESSURE; LUNG VASCULAR RESISTANCE; MALE; MITOSIS; NONHUMAN; PULMONARY HYPERTENSION; RAT; SMOOTH MUSCLE FIBER; VASCULAR REMODELING; ANIMAL; CELL COMMUNICATION; COMPARATIVE STUDY; CULTURE TECHNIQUE; DISEASE MODEL; DRUG EFFECTS; HYPERTENSION, PULMONARY; PATHOLOGY; PATHOPHYSIOLOGY; PULMONARY ARTERY; VASCULAR ENDOTHELIUM; WISTAR RAT;

ADRENERGIC BETA-1 RECEPTOR ANTAGONISTS; ANIMALS; BENZOPYRANS; CELL COMMUNICATION; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ETHANOLAMINES; HUMANS; HYPERTENSION, PULMONARY; MALE; METOPROLOL; MONOCROTALINE; MYOCYTES, SMOOTH MUSCLE; PULMONARY ARTERY; RATS; RATS, WISTAR; VASCULAR REMODELING;

EID: 84922830045     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2014.11.050     Document Type: Article

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