Filaggrin mutations in early- and late-onset atopic dermatitis

British Journal of Dermatology

Volumn 172, Issue 2, 2015, Pages 320-321

  Szegedi, A ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

FILAGGRIN; INTERMEDIATE FILAMENT PROTEIN;

ATOPIC DERMATITIS; COPY NUMBER VARIATION; EARLY ONSET ATOPIC DERMATITIS; ENVIRONMENTAL EXPOSURE; GENE LOSS; GENE MUTATION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; INCIDENCE; LATE ONSET ATOPIC DERMATITIS; LOSS OF FUNCTION MUTATION; NOTE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; REDUCTION; TH2 CELL; TH22 CELL; WILD TYPE; FEMALE; GENETICS; MALE; MUTATION;

DERMATITIS, ATOPIC; FEMALE; HUMANS; INTERMEDIATE FILAMENT PROTEINS; MALE; MUTATION;

EID: 84922819998     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/bjd.13534     Document Type: Note

References (5)

1. Irvine AD, McLean WH, Leung DY,. Filaggrin mutations associated with skin and allergic diseases. N Engl J Med 2011; 365: 1315-27.
2. Pellerin L, Henry J, Hsu CY, et al,. Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin. J Allergy Clin Immunol 2013; 131: 1094-102.
3. De Benedetto A, Kubo A, Beck LA,. Skin barrier disruption: a requirement for allergen sensitization? J Invest Dermatol 2012; 132: 949-63.
4. Mõcsai G, Gáspár K, Nagy G, et al,. Severe skin inflammation and filaggrin mutation similarly alter the skin barrier in patients with atopic dermatitis. Br J Dermatol 2014; 170: 617-24.
5. Rupnik H, Rijavec M, Korošec P,. Filaggrin loss-of-function mutations are not associated with atopic dermatitis that develops in late childhood or adulthood. Br J Dermatol 2015; 172: 455-61.