Hybrid lipid-capped mesoporous silica for stimuli-responsive drug release and overcoming multidrug resistance

ACS Applied Materials and Interfaces

Volumn 7, Issue 5, 2015, Pages 3342-3351

  Han, Ning ^a   Zhao, Qinfu ^a   Wan, Long ^a   Wang, Ying ^a   Gao, Yikun ^a   Wang, Pu ^b   Wang, Zhanyou ^b   Zhang, Jinghai ^a   Jiang, Tongying ^a   Wang, Siling ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b NORTHEASTERN UNIVERSITY   (China)

Author keywords

drug delivery; lipid; mesoporous silica; multidrug resistance; polymer; stimuli responsive release

Indexed keywords

BODY FLUIDS; CHEMOTHERAPY; CONTROLLED DRUG DELIVERY; COVALENT BONDS; DRUG DELIVERY; FUNCTIONAL POLYMERS; HYDROPHOBICITY; LIPIDS; MESOPOROUS MATERIALS; MOLAR RATIO; POLYMERS; SILICA; SILICA NANOPARTICLES; SULFUR COMPOUNDS;

CAPPED MESOPOROUS SILICA; ENHANCED PERMEABILITY AND RETENTION EFFECT; HYDROPHOBIC INTERACTIONS; INTRACELLULAR ACCUMULATION; MESOPOROUS SILICA; MULTIDRUG RESISTANCE; NARROW SIZE DISTRIBUTIONS; STIMULI-RESPONSIVE;

TARGETED DRUG DELIVERY;

ANTINEOPLASTIC ANTIBIOTIC; DELAYED RELEASE FORMULATION; DOXORUBICIN; MACROGOL DERIVATIVE; NANOCAPSULE; POLYETHYLENE GLYCOL 1000; SILICON DIOXIDE; TOCOPHEROL;

ADMINISTRATION AND DOSAGE; CELL SURVIVAL; CHEMISTRY; DELAYED RELEASE FORMULATION; DIFFUSION; DRUG EFFECTS; HUMAN; MCF 7 CELL LINE; MULTIDRUG RESISTANCE; NEOPLASMS, EXPERIMENTAL; PARTICLE SIZE; PATHOLOGY; POROSITY; ULTRASTRUCTURE;

ANTIBIOTICS, ANTINEOPLASTIC; CELL SURVIVAL; DELAYED-ACTION PREPARATIONS; DIFFUSION; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; HUMANS; MCF-7 CELLS; NANOCAPSULES; NEOPLASMS, EXPERIMENTAL; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POROSITY; SILICON DIOXIDE; TOCOPHEROLS;

EID: 84922796632     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/am5082793     Document Type: Article

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