The mirror neuron system and the strange case of Broca's area

Human Brain Mapping

Volumn 36, Issue 3, 2015, Pages 1010-1027

  Cerri, Gabriella ^a,b   Cabinio, Monia ^a,c   Blasi, Valeria ^a,c   Borroni, Paola ^a   Iadanza, Antonella ^c   Fava, Enrica ^a,b   Fornia, Luca ^a,b   Ferpozzi, Valentina ^a,b   Riva, Marco ^a,b   Casarotti, Alessandra ^a,b   Martinelli Boneschi, Filippo ^c   Falini, Andrea ^c   Bello, Lorenzo ^a,b  

^a UNIVERSITY OF MILAN   (Italy)

^b HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^c SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

Broca's area; Functional magnetic resonance imaging; Intraoperative brain mapping; Language; Mirror neurons; Motor control

Indexed keywords

ADULT; AGED; ARTICLE; CEREBELLUM; CONTROLLED STUDY; DIAGONAL BAND OF BROCA; ELECTROMYOGRAM; FEMALE; FRACTIONAL ANISOTROPY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HAND MUSCLE; HEMISPHERIC DOMINANCE; HUMAN; HUMAN EXPERIMENT; INFERIOR FRONTAL GYRUS; INFERIOR PARIETAL LOBULE; LATENT PERIOD; LEFT HEMISPHERE; MALE; MIDDLE AGED; MIDDLE FRONTAL GYRUS; MIRROR NEURON; MIRROR NEURON SYSTEM; MOTOR CONTROL; NEUROPHYSIOLOGY; NORMAL HUMAN; OBSERVATIONAL STUDY; OCCIPITAL GYRUS; PARIETAL CORTEX; POSTCENTRAL GYRUS; PRIMARY MOTOR CORTEX; PRIMARY SOMATOSENSORY CORTEX; PRIORITY JOURNAL; SEMANTICS; SPEECH; BRAIN MAPPING; BRAIN NEOPLASMS; BROCA AREA; ELECTROENCEPHALOGRAPHY; ELECTROMYOGRAPHY; ELECTROSTIMULATION; FRONTAL LOBE; INTRAOPERATIVE NEUROPHYSIOLOGICAL MONITORING; LANGUAGE; MOTOR ACTIVITY; NUCLEAR MAGNETIC RESONANCE IMAGING; PARIETAL LOBE; PATHOLOGY; PHYSIOLOGY; PROCEDURES; YOUNG ADULT;

ADULT; AGED; BRAIN MAPPING; BRAIN NEOPLASMS; BROCA AREA; ELECTRIC STIMULATION; ELECTROENCEPHALOGRAPHY; ELECTROMYOGRAPHY; FEMALE; FRONTAL LOBE; HUMANS; INTRAOPERATIVE NEUROPHYSIOLOGICAL MONITORING; LANGUAGE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MIRROR NEURONS; MOTOR ACTIVITY; PARIETAL LOBE; YOUNG ADULT;

EID: 84922785178     PISSN: 10659471     EISSN: 10970193     Source Type: Journal    
DOI: 10.1002/hbm.22682     Document Type: Article

References (63)

1. Amunts K, Zilles K (2012): Architecture and organizational principles of Broca's region. Trends Cogn Sciences 16:418-426.
2. Amunts K, Schleicher A, Burgel U, Mohlberg H, Uylings HBM, Zilles K (1999): Broca's region revisited: Cytoarchitecture and intersubject variability. J Comput Neurol 412:319-341.
3. Aziz-Zadeh L, Cattaneo L, Rochat M, Rizzolatti G (2005): Covert speech arrest induced by rTMS over both motor and non motor left hemisphere frontal sites. J Cogn Neurosci 17:928-938.
4. Bello L, Riva M, Fava E, Ferpozzi V, Castellano A, Raneri F, Pessina F, Bizzi A, Falini A, Cerri G (2014): Tailoring neurophysiological strategies with clinical context enhances resection and safety and expands indications in gliomas involving motor pathways. Neuro Oncol 16:1110-1128. doi:10.1093/neuonc/not327.
5. Binkofski F, Buccino G, Posse S, Seitz RJ, Rizzolatti G, Freund HJ (1999): A fronto-parietal circuit for object manipulation in man: Evidence from an fMRI-study. Eur J Neurosci 11:3276-3286.
6. Bouchard KE, Mesgarani N, Johnson K, Chang EF (2013): Functional organization of human sensory motor cortex for speech articulation. Nature 495:327-332.
7. Buccino G, Vogt S, Ritzl A, Fink GR, Zilles K, Rizzolatti G (2004): Neural circuits underlying imitation learning of hand actions: An event-related fMRI study. Neuron 42:323-334.
8. Cabinio M, Blasi V, Borroni P, Montagna M, Iadanza A, Falini A, Cerri G (2010): The shape of motor resonance: Right or left handed? NeuroImage 51:313-323.
9. Cerri G, Shimazu H, Maier MA, Lemon RN (2003): Facilitation from ventral premotor cortex of primary motor cortex outputs to macaque hand muscles. J Neurophysiol 90:832-842.
10. de Zubicaray G, Postle N, McMahon K, Meredith M, Ashton R (2010): Mirror neurons, the representation of word meaning and the foot of the third left frontal convolution. Brain Lang 112:77-84.
11. Decety J, Grèzes J, Costes N, Perani D, Jeannerod M, Procyk E, Grassi F, Fazio F (1997): Brain activity during observation of actions: Influence of action content and subject's strategy. Brain 120:1763-1777.
12. Dinstein I, Hasson U, Rubin N, Heeger DJ (2007): Brain areas selective for both observed and executed movements. J Neurophysiol 98:1415-1427.
13. Dinstein I, Thomas C, Behrmann M, Heeger DJ (2008): A mirror up to nature. Curr Biol 18:R13-R18.
14. Dronkers N (1996): A new brain region for coordinating speech articulation. Nature 384:159-116.
15. Duffau H, Capelle L, Denvil D, Gatignol P, Sichez N, Lopes M, Sichez J-P, Van Effenterrea R (2003): The role of dominant premotor cortex in language: A study using intraoperative functional mapping in awake patients. NeuroImage 20:1903-1914.
16. Duncan J, Owen AM (2000): Common regions of the human frontal lobe recruited by diverse cognitive demands. Trends Neurosci 23:475-483.
17. Espadaler J, Rogiæ M, Deletis V, Leon A, Quijada C, Conesa G (2012): Representation of cricothyroid muscles at the primary motor cortex (M1) in healthy subjects mapped by navigated transcranial magnetic stimulation (nTMS). Clin Neurophysiol 123:2205-2211.
18. Fazio P, Cantagallo A, Craighero L, D'Ausilio A, Roy AC, Pozzo T, Calzolari F, Granieri E, Fadiga L (2009): Encoding of human action in Broca's area. Brain 132:1980-1988.
19. Fedorenko E, Duncan J, Kanwisher N (2012): Language-selective and domain-general regions lie side by side within Broca's area. Curr Biol 22:2059-2062.
20. Freund HJ (1996): Functional organization of the human supplementary motor area and dorsolateral premotor cortex. Adv Neurol 70:263-269.
21. Gallese V, Fadiga L, Fogassi L, Rizzolatti G (1996): Action recognition in the premotor cortex. Brain 119:593-609.
22. Gazzola V, Keysers C (2009): The observation and execution of actions share motor and somatosensory voxels in all tested subjects: Single-subject analyses of unsmoothed fMRI data. Cereb Cortex 19:1239-1255.
23. Gazzola V, Rizzolatti G, Wicker B, Keysers C (2007): The anthropomorphic brain: The mirror neuron system responds to human and robotic actions. NeuroImage 35:1674-1684.
24. Gerardin E, Sirigu A, Lehericy S, Pauline J-B, Gaymard B, Marsault C, Agid Y, Le Bihan D (2000): Partially overlapping neural networks for real and imagined hand movements. Cereb Cortex 10:1093-1104.
25. Gerlach C, Law I, Paulson OB (2002): When action turns into words. Activation of motor-based knowledge during categorization of manipulable objects. J Cogn Neurosci 14:1230-1239.
26. Grafton ST, Arbib MA, Fadiga L, Rizzolatti G (1996): Localization of grasp representations in humans by positron emission tomography. 2. Observation compared with imagination. Exp Brain Res 112:103-111.
27. Grèzes J, Armony JL, Rowe J, Passingham RE (2003): Activations related to "mirror" and "canonical" neurones in the human brain: An fMRI study. NeuroImage 18:928-937.
28. Hauk O, Johnsrude I, Pulvermuller F (2004): Somatotopic Representation of action words in human motor and premotor cortex. Neuron 41:301-307.
29. Heim S, Eickhoff SB, Amunts K (2008): Specialization in Broca's region for semantic phonological and syntactic fluency? NeuroImage 40:1362-1368.
30. Hickok G (2012): Computational neuroanatomy of speech production. Nat Rev Neurosci 13:135-145.
31. Hillis AE, Work M, Barker PB, Jacobs MA, Breese EL, Maurer K (2004): Re-examining the brain regions crucial for orchestrating speech articulation. Brain 127:1479-1487.
32. Iacoboni M, Woods RP, Brass M, Bekkering H, Mazziotta JC, Rizzolatti G (1999): Cortical mechanisms of human imitation. Science 286:2526-2528.
33. Juch H, Zimine I, Seghier ML, Lazeyras F, Fasel JHD (2005): Anatomical variability of the lateral frontal lobe surface implication for intersubject variability in language neuroimaging. NeuroImage 24:504-514.
34. Kent RD (2000): Research on speech motor control and its disorders: A review and prospective. J Commun Disord 33:391-427.
35. Koechlin E, Jubault T (2006): Broca's area and the hierarchical organization of human behavior. Neuron 50:963-974.
36. Kraskov A, Dancause N, Quallo MM, Shepherd S, Lemon RN (2009): Corticospinal neurons in macaque ventral premotor cortex with mirror properties: A potential mechanism for action suppression? Neuron 64:922-930.
37. Kraskov A, Prabhu G, Quallo MM, Lemon RN, Brochier T (2011): Ventral premotor-motor cortex interactions in the macaque monkey during grasp: Response of single neurons to intracortical microstimulation. J Neurosci 31:8812-8821.
38. Levy F (2012): Mirror neurons, birdsong and human language: A hypothesis. Front Psychiatry 2:1-7.
39. Lüders HO, Dinner DS, Morris HH, Wyllie E, Comair YG (1995): Cortical electrical stimulation in humans. The negative motor areas. Adv Neurol 67:115-129.
40. Mantini D, Hasson U, Betti V, Perrucci MG, Romani GL, Corbetta M, Orban GA, Vanduffel1 W (2012): Interspecies activity correlations reveal functional correspondence between monkey and human brain areas. Nat Methods 9:277-282.
41. Mengotti P, Corradi-Dell'Acqua C, Negri GAL, Ukmar M, Pesavento V, Rumiati RI (2013): Selective imitation impairments differentially interact with language processing. Brain 136:2602-2618.
42. Molenberghs P, Cunnington R, Mattingley JB (2012): Brain regions with mirror properties: A meta-analysis of 125 human fMRI studies. Neurosci Biobehav Rev 36:341-349.
43. Molnar-Szakacs I, Iacoboni M, Koski L, Mazziotta JC (2005): Functional segregation within pars opercularis of the inferior frontal gyrus: Evidence from fMRI studies of imitation and action observation. Cereb Cortex 15:986-994.
44. Morin O, Grezes J (2008): What is "mirror" in the premotor cortex? A review. Clin Neurophysiol 38:189-195.
45. Moro A (2014): On the similarity between syntax and actions. Trends Cogn Sci 18:109-110.
46. Nelissen K, Luppino G, Vanduffel W, Rizzolatti G, Orban GA (2005): Observing others: Multiple action representation in the frontal lobe. Science 310:332-336.
47. Nishitani N, Hari R (2000): Temporal dynamics of cortical representation for action. Proc Natl Acad Sci USA 97:913-918.
48. Nishitani N, Hari R (2002): Viewing lip forms: Cortical dynamics. Neuron 36:1211-1220.
49. Oosterhof NN, Tipper SP, Downing PE (2013): Crossmodal and action-specific: Neuroimaging the human mirror neuron system. Trends Cogn Sci 17:311-318.
50. Papagno C, Della Sala S, Basso A (1993): Ideomotor apraxia without aphasia and aphasia without apraxia: The anatomical support for a double dissociation. J Neurol Neurosurg Psychiatry 56:286-289.
51. Petrides M, Pandya ND (2001): Comparative cytoarchitectonic analysis of the human and the macaque ventrolateral prefrontal cortex and corticocortical connection patterns in the monkey. Eur J Neurosci 16:291-310.
52. Petrides M, Cadoret G, Mackey S (2005): Orofacial somatomotor responses in the macaque monkey homologue of Broca's area. Nature 435:1235-1238.
53. Porter R, Lemon RN (1993): Corticospinal Function and Voluntary Movement. Oxford: Oxford University Press.
54. Press C, Weiskopf N, Kilner JM (2012): Dissociable roles of human inferior frontal gyrus during action execution and observation. Neuroimage 15:1671-1677.
55. Quiñones-Hinojosa A, Ojemann SG, Sanai N, Dillon WP, Berger MS (2003): Preoperative correlation of intraoperative cortical mapping with magnetic resonance imaging landmarks to predict localization of the Broca area. J Neurosurg 99:311-318.
56. Rizzolatti G, Arbib MA (1998): Language within our grasp. Trends Neurosci 21:188-204.
57. Rizzolatti G, Craighero L (2004): The mirror-neuron system. Ann Rev Neurosci 27:169-192.
58. Sereno MI, Tootell RBH (2005): From monkeys to humans: What do we now know about brain homologies? Curr Opin Neurobiol 15:135-144.
59. Skirboll SS, Ojemann GA, Berger MS, Lettich E, Winn HR (1996): Functional cortex and subcortical white matter located within gliomas. Neurosurgery 38:678-685.
60. Tandon N, Narayana S, Lancaster JL, Brown S, Dodd S, Vollmer DG, Ingham R, Ingham J, Liotti M, Fox PT (2003): CNS Resident Award: Role of the lateral premotor cortex in articulation. Clin Neurosurg 50:341-349.
61. Tettamanti M, Buccino M, Saccuman, MC, Gallese V, Danna M, Scifo P, Fazio F, Rizzolatti G, Cappa SF, Perani D (2005): Listening to action-related sentences activates fronto-parietal motor circuits. J Cogn Neurosci 17:273-281.
62. Toni I, de Lange FP, Noordzij ML, Hagoort P (2008): Language beyond action. J Physiol Paris 102:71-79.
63. Turella L, Pierno A, Tubaldi F, Castiello U (2009): Mirror neurons in humans: Consisting or confounding evidence? Brain Lang 108:10-21.