Asymmetric synthesis of tetrahydroisoquinolines by enzymatic Pictet-Spengler reaction

Bioscience, Biotechnology and Biochemistry

Volumn 78, Issue 4, 2014, Pages 701-707

  Nishihachijo, Masakatsu ^a   Hirai, Yoshinori ^a   Kawano, Shigeru ^a   Nishiyama, Akira ^a   Minami, Hiromichi ^b   Katayama, Takane ^b   Yasohara, Yoshihiko ^a   Sato, Fumihiko ^c   Kumagai, Hidehiko ^b  

^a KANEKA CORPORATION   (Japan)

^b ISHIKAWA PREFECTURAL UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Isoquinoline alkaloid; Norcoclaurine synthase; Pictet Spengler reaction

Indexed keywords

ALDEHYDES; ALKALOIDS; ESCHERICHIA COLI; METABOLITES; NITROGEN COMPOUNDS;

ASYMMETRIC SYNTHESIS; BENZYLISOQUINOLINE ALKALOIDS; ENANTIOMER EXCESS; ISOQUINOLINES; PICTET-SPENGLER REACTIONS; SUBSTRATE SPECIFICITY; SYNTHASES; TETRAHYDROISOQUINOLINES;

ENZYMES;

COPTIS JAPONICA; ESCHERICHIA COLI;

1,2,3,4-TETRAHYDROISOQUINOLINE; LIGASE; NORCOCLAURINE SYNTHASE; TETRAHYDROISOQUINOLINE DERIVATIVE;

CHEMISTRY; COPTIS; ENZYME SPECIFICITY; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; LIGHT RELATED PHENOMENA; METABOLISM; STEREOISOMERISM; SYNTHESIS;

CARBON-NITROGEN LIGASES; CHEMISTRY TECHNIQUES, SYNTHETIC; COPTIS; ESCHERICHIA COLI; OPTICAL PROCESSES; STEREOISOMERISM; SUBSTRATE SPECIFICITY; TETRAHYDROISOQUINOLINES;

EID: 84922782409     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1080/09168451.2014.890039     Document Type: Article

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