Somatic MED12 mutations are associated with poor prognosis markers in chronic lymphocytic leukemia

Oncotarget

Volumn 6, Issue 3, 2015, Pages 1884-1888

  Kämpjärvi, Kati ^a   Järvinen, Tiina M ^b   Heikkinen, Tuomas ^a   Ruppert, Amy S ^b   Senter, Leigha ^b   Hoag, Kevin W ^b   Dufva, Olli ^a   Kontro, Mika ^c   Rassenti, Laura ^d   Hertlein, Erin ^b   Kipps, Thomas J ^d   Porkka, Kimmo ^c   Byrd, John C ^b   de la Chapelle, Albert ^b   Vahteristo, Pia ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b OHIO STATE UNIVERSITY   (United States)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Cancer genetics; Chronic lymphocytic leukemia; MED12; Prognosis; Somatic mutation

Indexed keywords

CYCLIN C; CYCLIN DEPENDENT KINASE 8; IMMUNOGLOBULIN HEAVY CHAIN; PROTEIN KINASE ZAP 70; MED12 PROTEIN, HUMAN; MEDIATOR COMPLEX;

ADULT; AGED; ARTICLE; CHRONIC LYMPHATIC LEUKEMIA; CODON; ENZYME ACTIVITY; EXON; FEMALE; GENETIC SCREENING; HUMAN; LEUKEMOGENESIS; MAJOR CLINICAL STUDY; MALE; MED12 GENE; MISSENSE MUTATION; PROGNOSIS; PROTEIN EXPRESSION; SOMATIC MUTATION; TUMOR GENE; VERY ELDERLY; AMINO ACID SEQUENCE; GENETICS; METABOLISM; MIDDLE AGED; MOLECULAR GENETICS; MUTATION;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; FEMALE; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MEDIATOR COMPLEX; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; PROGNOSIS;

EID: 84922702326     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2753     Document Type: Article

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