메뉴 건너뛰기




Volumn 34, Issue 6, 2013, Pages 616-622

Compensatory activation of estrogen receptor α signaling in acquired resistance to lapatinib of HER2-overexpressing/ERα-positive breast cancer cells

Author keywords

Breast neoplasms; erbB 2 receptor; Estrogen receptor alpha; Lapatinib; Neoplasm drug resistance

Indexed keywords

3 (4, 5 DIMETHYL 2 THIAZOLYL) 2, 5 DIPHENYLTETRAZOLIUM BROMIDE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR ALPHA; FULVESTRANT; LAPATINIB; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROGESTERONE RECEPTOR; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG;

EID: 84922686529     PISSN: 0258879X     EISSN: None     Source Type: Journal    
DOI: 10.3724/Sp.J.1008.2013.00616     Document Type: Article
Times cited : (1)

References (24)
  • 1
    • 77149145162 scopus 로고    scopus 로고
    • Characterizing the HER2/neu status and metastatic potential of breast cancerstem/ progenitor cells [J]
    • Pommier S J, Quan G G, Christante D, Muller P, Newell A E, Olson SB, et al. Characterizing the HER2/neu status and metastatic potential of breast cancerstem/ progenitor cells [J], Ann Surg 0ncol, 2010,17 613-623.
    • (2010) Ann Surg 0ncol , vol.17 , pp. 613-623
    • Pommier, S.J.1    Quan, G.G.2    Christante, D.3    Muller, P.4    Newell, A.E.5    Olson, S.B.6
  • 3
    • 82155187061 scopus 로고    scopus 로고
    • Different mechanisms for resistance to tras-tuzumab versus lapatinib in HER2-positive breast canc-ers-role of estrogen receptor and HER2 reactivation [J]
    • Wang Y C, Morrison G, Gillihan R, Guo J, Ward R M, Fu X, et al. Different mechanisms for resistance to tras-tuzumab versus lapatinib in HER2-positive breast canc-ers-role of estrogen receptor and HER2 reactivation [J], Breast Cáncer Research,2011, 13:R121.
    • (2011) Breast Cáncer Research , vol.13
    • Wang, Y.C.1    Morrison, G.2    Gillihan, R.3    Guo, J.4    Ward, R.M.5    Fu, X.6
  • 4
    • 33646746413 scopus 로고    scopus 로고
    • A modil of acquired autoresistance to a potent ErbB2 tyrosine kinase inhibitor and a therapeutic strat-egy to prevent its onset in breast cancer[J]
    • Xia W, Bacus S, Hegde P, Husain I, Strum J, Liu L, et al. A modil of acquired autoresistance to a potent ErbB2 tyrosine kinase inhibitor and a therapeutic strat-egy to prevent its onset in breast cancer[J], Proc Natl Acad Scf USA,2006,103:7795-7800.
    • (2006) Proc Natl Acad Scf USA , vol.103 , pp. 7795-7800
    • Xia, W.1    Bacus, S.2    Hegde, P.3    Husain, I.4    Strum, J.5    Liu, L.6
  • 5
    • 42649130333 scopus 로고    scopus 로고
    • Her2 cross talk and therapeutic resistance in breast cancer[J]
    • Bender L M, Nahta R. Her2 cross talk and therapeutic resistance in breast cancer[J], FrontBiosci, 2008, 13: 3906-3912.
    • (2008) FrontBiosci , vol.13 , pp. 3906-3912
    • Bender, L.M.1    Nahta, R.2
  • 6
    • 51549101729 scopus 로고    scopus 로고
    • A phase I and pharmacokinetic study of lapatinib in combination with letrozole in pa-tients with advanced cancer[J]
    • Chu QS, Cianfrocca ME, Goldstein LJ, Gale M, Mur-ray N, Loftiss J, et al. A phase I and pharmacokinetic study of lapatinib in combination with letrozole in pa-tients with advanced cancer[J], Clin Cáncer Res,2008, 14:4484-4490.
    • (2008) Clin Cáncer Res , vol.14 , pp. 4484-4490
    • Chu, Q.S.1    Cianfrocca, M.E.2    Goldstein, L.J.3    Gale, M.4    Mur-Ray, N.5    Loftiss, J.6
  • 7
    • 77952826677 scopus 로고    scopus 로고
    • Lapatinib in the treatment of hormone receptor-positive/ErbB2-positive breast cancer[J]
    • s1
    • Bauerfeind I, Elling D, Heinemann V. Lapatinib in the treatment of hormone receptor-positive/ErbB2-positive breast cancer[J], Breast Care (Basel),2010,5(s1);13-15.
    • (2010) Breast Care (Basel) , vol.5 , pp. 13-15
    • Bauerfeind, I.1    Elling, D.2    Heinemann, V.3
  • 9
    • 78650492709 scopus 로고    scopus 로고
    • Lapatinib for breast cáncer: A review of the current literature[J]
    • Macfarlane R J, Gelmon K A. Lapatinib for breast cáncer: a review of the current literature[J]. Expert 0pin Drug Saf,2011,10:109-121.
    • (2011) Expert 0pin Drug Saf , vol.10 , pp. 109-121
    • Macfarlane, R.J.1    Gelmon, K.A.2
  • 10
    • 76449104021 scopus 로고    scopus 로고
    • Molecular predictors of response to trastuzumab and lapatinib in breast cáncer [J]
    • Esteva F J, Yu D, Hung M C, Hortobagyi G N. Molecular predictors of response to trastuzumab and lapatinib in breast cáncer [J]. Nat Rev Clin 0ncol, 2010, 7: 98-107.
    • (2010) Nat Rev Clin 0ncol , vol.7 , pp. 98-107
    • Esteva, F.J.1    Yu, D.2    Hung, M.C.3    Hortobagyi, G.N.4
  • 11
    • 46449113024 scopus 로고    scopus 로고
    • Efficacy and safety of lapatinib as first-line therapy for ErbB2-amplified locally advancedor metastatic breast cáncer[J]
    • Gómez H L, Do val D C, Chavez M A, Ang P C, Aziz Z, Nag S, et al. Efficacy and safety of lapatinib as first-line therapy for ErbB2-amplified locally advancedor metastatic breast cáncer[J], J Clin 0ncol,2008,26:2999-3005
    • (2008) J Clin 0ncol , vol.26 , pp. 2999-3005
    • Gómez, H.L.1    Do val, D.C.2    Chavez, M.A.3    Ang, P.C.4    Aziz, Z.5    Nag, S.6
  • 12
    • 56449111358 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase hyper-activation results in lapatinib resistance that is reversed by the mT0R/phosphatidylinositol3-kinase inhibitor NVP-BEZ235[J]
    • Eichhorn P J, Gili M, Scaltriti M, Serra V, Guzman M, Nijkamp W, et al. Phosphatidylinositol 3-kinase hyper-activation results in lapatinib resistance that is reversed by the mT0R/phosphatidylinositol3-kinase inhibitor NVP-BEZ235[J], Cáncer Res,2008,68:9221-9230.
    • (2008) Cáncer Res , vol.68 , pp. 9221-9230
    • Eichhorn, P.J.1    Gili, M.2    Scaltriti, M.3    Serra, V.4    Guzman, M.5    Nijkamp, W.6
  • 14
    • 33846552656 scopus 로고    scopus 로고
    • Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3 [J]
    • Sergina N V, Rausch M, Wang D, Blair J, Hann B, Shokat KM, et al. Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3 [J], Nature,2007,445:437-441.
    • (2007) Nature , vol.445 , pp. 437-441
    • Sergina, N.V.1    Rausch, M.2    Wang, D.3    Blair, J.4    Hann, B.5    Shokat, K.M.6
  • 15
    • 79955658799 scopus 로고    scopus 로고
    • Resistance to HER2 inhibitors: Is addition better than substitution? Rationale for the hypothetical concept of drug sedimen-tation[J]
    • Campone M, Juin P, André F, Bachelot T. Resistance to HER2 inhibitors: is addition better than substitution? Rationale for the hypothetical concept of drug sedimen-tation[J], Crit Rev 0ncol Hematol,2011,78:195-205.
    • (2011) Crit Rev 0ncol Hematol , vol.78 , pp. 195-205
    • Campone, M.1    Juin, P.2    André, F.3    Bachelot, T.4
  • 16
    • 70149109569 scopus 로고    scopus 로고
    • Novll mechanism of lapatinib resistance in HER2-positive breast tumor cells: Activation of AXL [J]
    • Liu L, Greger J, Shi H, Liu Y, Greshock J, Annan R, et al. Novll mechanism of lapatinib resistance in HER2-positive breast tumor cells: activation of AXL [J]. Cáncer Res,2009,69:6871-6878.
    • (2009) Cáncer Res , vol.69 , pp. 6871-6878
    • Liu, L.1    Greger, J.2    Shi, H.3    Liu, Y.4    Greshock, J.5    Annan, R.6
  • 17
    • 79953162369 scopus 로고    scopus 로고
    • Switching addictions between HER2 and FGFR2 in HER2-positive breast tumor cells: FG-FR2 as a potential target for salvage after lapatinib faü-ure[J]
    • Azuma K, Tsurutani J, Sakai K, Kaneda H, Fujisaka Y, Takeda M, et al. Switching addictions between HER2 and FGFR2 in HER2-positive breast tumor cells: FG-FR2 as a potential target for salvage after lapatinib faü-ure[J], Biochem Biophys Res Commun, 2011, 407: 219-224.
    • (2011) Biochem Biophys Res Commun , vol.407 , pp. 219-224
    • Azuma, K.1    Tsurutani, J.2    Sakai, K.3    Kaneda, H.4    Fujisaka, Y.5    Takeda, M.6
  • 18
    • 85027940454 scopus 로고    scopus 로고
    • Phosphoproteomic mass spectrometry profiling links Src family kinases to escape from HER2 tyrosine kinase inhibition[J]
    • Rexer B N, Ham A J, Rinehart C, Hill S, Granja-Ingram Nde M, González-Angulo A M, et al. Phosphoproteomic mass spectrometry profiling links Src family kinases to escape from HER2 tyrosine kinase inhibition[J], 0nco-gene,2011,30;4163-4174.
    • (2011) 0nco-gene , vol.30 , pp. 4163-4174
    • Rexer, B.N.1    Ham, A.J.2    Rinehart, C.3    Hill, S.4    Granja-Ingramnde, M.5    González-Angulo, A.M.6
  • 19
    • 4544369383 scopus 로고    scopus 로고
    • Forkhead box transcription factor F0X03aregulates estrogen receptor alpha ex-pression and is repressed by the Her-2/neu/phosphati-dylinositol 3-kinase/Akt signaling pathway [J]
    • Guo S, Sonenshein G E. Forkhead box transcription factor F0X03aregulates estrogen receptor alpha ex-pression and is repressed by the Her-2/neu/phosphati-dylinositol 3-kinase/Akt signaling pathway [J]. Mol Cell Biol,2004,24: 8681-8690.
    • (2004) Mol Cell Biol , vol.24 , pp. 8681-8690
    • Guo, S.1    Sonenshein, G.E.2
  • 20
    • 0041343273 scopus 로고    scopus 로고
    • Roles of the P--3K and MEK pathways in Ras-mediated chemoresis-tance in breast cáncer cells[J]
    • Jin W, Wu L, Liang K, Liu B, Lu Y, Fan Z. Roles of the P--3K and MEK pathways in Ras-mediated chemoresis-tance in breast cáncer cells[J], British J Cáncer, 2003, 89:185-191.
    • (2003) British J Cáncer , vol.89 , pp. 185-191
    • Jin, W.1    Wu, L.2    Liang, K.3    Liu, B.4    Lu, Y.5    Fan, Z.6
  • 21
    • 0037030521 scopus 로고    scopus 로고
    • MAP kinase/ estrogen receptor cross-talk enhances estrogen-mediated signaling and tumor growth but does not confer tamoxifen resistance [J]
    • Atanaskova N, Keshamouni V G, Krueger J S, Schwartz J A, Miller F, Reddy K B. MAP kinase/ estrogen receptor cross-talk enhances estrogen-mediated signaling and tumor growth but does not confer tamoxifen resistance [J]. 0ncogene,2002,21: 4000-4008.
    • (2002) 0ncogene , vol.21 , pp. 4000-4008
    • Atanaskova, N.1    Keshamouni, V.G.2    Krueger, J.S.3    Schwartz, J.A.4    Miller, F.5    Reddy, K.B.6
  • 22
    • 34147105901 scopus 로고    scopus 로고
    • Cross-talk between ER and HER2 in breast carcinoma[J]
    • Zora N, Dragica N. Cross-talk between ER and HER2 in breast carcinoma[J]. Archive 0ncol, 2006, 14: 146-150.
    • (2006) Archive 0ncol , vol.14 , pp. 146-150
    • Zora, N.1    Dragica, N.2
  • 23
    • 15744393640 scopus 로고    scopus 로고
    • Regulation of signal transduction pathways by estrogen and progesterone[J]
    • Edwards D P. Regulation of signal transduction pathways by estrogen and progesterone[J], Ann Rev Phyii-ol,2005, 67: 335-376.
    • (2005) Ann Rev Phyii-ol , vol.67 , pp. 335-376
    • Edwards, D.P.1
  • 24
    • 33947401482 scopus 로고    scopus 로고
    • Inte-gration of rapid signaling events with steroid hormone receptor action in breast and prostate cáncer[J]
    • Lange C A, Gioeli D, Hammes S R, Marker P C. Inte-gration of rapid signaling events with steroid hormone receptor action in breast and prostate cáncer[J]. Ann Rev Physiol,2007,69:171-199.
    • (2007) Ann Rev Physiol , vol.69 , pp. 171-199
    • Lange, C.A.1    Gioeli, D.2    Hammes, S.R.3    Marker, P.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.