Optimization of pilocarpine-mediated seizure induction in immunodeficient nodscid mice

Epilepsy Research

Volumn 109, Issue 1, 2015, Pages 114-118

  Leung, Amanda ^a,b   Ahn, Sandra ^a,b   Savvidis, George ^a,b   Kim, Yeachan ^a,b   Iskandar, Danielle ^a,b   Luna, Maria Jose ^a,b   Kim, Kwang Soo ^a,b   Cunningham, Miles ^a   Chung, Sangmi ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

Mossy fiber sprouting; NodScid mice; Pilocarpine; Seizure; Temporal lobe epilepsy

Indexed keywords

PILOCARPINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DOSE RESPONSE; ELECTROENCEPHALOGRAM; EPILEPTIC STATE; FEMALE; HISTOLOGY; IMMUNE DEFICIENCY; MALE; MOSSY FIBER SPROUTING; MOUSE; MOUSE STRAIN; NERVE SPROUTING; NONHUMAN; PROCESS OPTIMIZATION; RECURRENT DISEASE; SURVIVAL RATE; TEMPORAL LOBE EPILEPSY; ANIMAL; DISEASE MODEL; ELECTRODE IMPLANT; ELECTROENCEPHALOGRAPHY; HIPPOCAMPAL MOSSY FIBER; IMMUNOHISTOCHEMISTRY; PATHOLOGY; PATHOPHYSIOLOGY; SCID MOUSE; VIDEORECORDING;

ANIMALS; DISEASE MODELS, ANIMAL; ELECTRODES, IMPLANTED; ELECTROENCEPHALOGRAPHY; EPILEPSY, TEMPORAL LOBE; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; MICE, SCID; MOSSY FIBERS, HIPPOCAMPAL; PILOCARPINE; STATUS EPILEPTICUS; VIDEO RECORDING;

EID: 84922682865     PISSN: 09201211     EISSN: 18726844     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2014.10.016     Document Type: Article

References (22)

1. Baraban S.C., Southwell D.G., Estrada R.C., Jones D.L., Sebe J.Y., Alfaro-Cervello C., Garcia-Verdugo J.M., Rubenstein J.L., Alvarez-Buylla A. Reduction of seizures by transplantation of cortical GABAergic interneuron precursors into Kv1.1 mutant mice. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:15472-15477.
2. Borges K., Gearing M., McDermott D.L., Smith A.B., Almonte A.G., Wainer B.H., Dingledine R. Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model. Exp. Neurol. 2003, 182:21-34.
3. Christoph C.H. Temporal lobe resection - does the prospect of seizure freedom outweigh the cognitive risks?. Nat. Clin. Pract. Neurol. 2008, 4:66-67.
4. Costa-Ferro Z.S., Souza B.S., Leal M.M., Kaneto C.M., Azevedo C.M., da Silva I.C., Soares M.B., Ribeiro-dos-Santos R., Dacosta J.C. Transplantation of bone marrow mononuclear cells decreases seizure incidence, mitigates neuronal loss and modulates pro-inflammatory cytokine production in epileptic rats. Neurobiol. Dis. 2012, 46:302-313.
5. Cramer J.A., Mintzer S., Wheless J., Mattson R.H. Adverse effects of antiepileptic drugs: a brief overview of important issues. Expert Rev. Neurother. 2010, 10:885-891.
6. Curia G., Longo D., Biagini G., Jones R.S., Avoli M. The pilocarpine model of temporal lobe epilepsy. J. Neurosci. Methods 2008, 172:143-157.
7. Engel J. A Proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE task force on classification and terminology. Epilepsia 2001, 42:796-803.
8. Engel J. Epilepsy in the world today: medical point of view. Epilepsia 2002, 43(Suppl. 6):12-13.
9. Fabene P.F., Laudanna C., Constantin G. Leukocyte trafficking mechanisms in epilepsy. Mol. Immunol. 2013, 55:100-104.
10. Fine A., Meldrum B.S., Patel S. Modulation of experimentally induced epilepsy by intracerebral grafts of fetal GABAergic neurons. Neuropsychologia 1990, 28:627-634.
11. Groticke I., Hoffmann K., Loscher W. Behavioral alterations in the pilocarpine model of temporal lobe epilepsy in mice. Exp. Neurol. 2007, 207:329-349.
12. Hattiangady B., Rao M.S., Shetty A.K. Grafting of striatal precursor cells into hippocampus shortly after status epilepticus restrains chronic temporal lobe epilepsy. Exp. Neurol. 2008, 212:468-481.
13. Hunt R.F., Girskis K.M., Rubenstein J.L., Alvarez-Buylla A., Baraban S.C. GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior. Nat. Neurosci. 2013, 16:692-697.
14. Lindvall O., Bjorklund A. Intracerebral grafting of inhibitory neurons. A new strategy for seizure suppression in the central nervous system. Adv. Neurol. 1992, 57:561-569.
15. Loscher W., Ebert U., Lehmann H., Rosenthal C., Nikkhah G. Seizure suppression in kindling epilepsy by grafts of fetal GABAergic neurons in rat substantia nigra. J. Neurosci. Res. 1998, 51:196-209.
16. Louboutin J.P., Chekmasova A., Marusich E., Agrawal L., Strayer D.S. Role of CCR5 and its ligands in the control of vascular inflammation and leukocyte recruitment required for acute excitotoxic seizure induction and neural damage. FASEB J. 2011, 25:737-753.
17. Marchi N., Granata T., Janigro D. Inflammatory pathways of seizure disorders. Trends Neurosci. 2014, 37:55-65.
18. Mazzuferi M., Kumar G., Rospo C., Kaminski R.M. Rapid epileptogenesis in the mouse pilocarpine model: video-EEG, pharmacokinetic and histopathological characterization. Exp. Neurol. 2012, 238:156-167.
19. Racine R.J. Modification of seizure activity by electrical stimulation II. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 1972, 32:281-294.
20. Shamim S., Wiggs E., Heiss J., Sato S., Liew C., Solomon J., Theodore W.H. Temporal lobectomy: resection volume, neuropsychological effects, and seizure outcome. Epilepsy Behav. 2009, 16:311-314.
21. Shibley H., Smith B.N. Pilocarpine-induced status epilepticus results in mossy fiber sprouting and spontaneous seizures in C57BL/6 and CD-1 mice. Epilepsy Res. 2002, 49:109-120.
22. Winawer M.R., Makarenko N., McCloskey D.P., Hintz T.M., Nair N., Palmer A.A., Scharfman H.E. Acute and chronic responses to the convulsant pilocarpine in DBA/2J and A/J mice. Neuroscience 2007, 149:465-475.