An electrochemical aptasensor for thrombin detection based on the recycling of exonuclease III and double-stranded DNA-templated copper nanoparticles assisted signal amplification

Analytica Chimica Acta

Volumn 860, Issue , 2015, Pages 23-28

  Zhao, Jing ^a   Xin, Meiling ^a   Cao, Ya ^a   Yin, Yongmei ^b   Shu, Yongqian ^b   Ma, Wenli ^c  

^a SHANGHAI UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^c SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Double stranded DNA templated copper nanoparticles; Electrochemical aptasensor; Exonuclease III; Signal amplification; Thrombin

Indexed keywords

AMPLIFICATION; COPPER; DIAGNOSIS; DNA; ENZYMES; METAL IONS; METAL NANOPARTICLES;

ELECTROCHEMICAL APTASENSOR; EXONUCLEASE III; SIGNAL AMPLIFICATIONS; TEMPLATED; THROMBIN;

ELECTROCHEMICAL ELECTRODES;

1,2 PHENYLENEDIAMINE; COPPER ION; COPPER NANOPARTICLE; DOUBLE STRANDED DNA; EXODEOXYRIBONUCLEASE III; PEPTIDE APTAMER; THROMBIN; APTAMER; COPPER; DNA; EXODEOXYRIBONUCLEASE; METAL NANOPARTICLE;

3' UNTRANSLATED REGION; ARTICLE; BASE PAIRING; BIOSENSOR; BLOOD SAMPLING; CATALYSIS; CONTROLLED STUDY; DISSOLUTION; DNA TEMPLATE; ELECTROCHEMICAL APTASENSOR; LIMIT OF DETECTION; OXIDATION; SENSITIVITY AND SPECIFICITY; SIGNAL DETECTION; STEREOCHEMISTRY; CHEMISTRY; DEVICES; ELECTROCHEMICAL ANALYSIS; ELECTRODE; METABOLISM; NUCLEIC ACID HYBRIDIZATION;

APTAMERS, NUCLEOTIDE; COPPER; DNA; ELECTROCHEMICAL TECHNIQUES; ELECTRODES; EXODEOXYRIBONUCLEASES; METAL NANOPARTICLES; NUCLEIC ACID HYBRIDIZATION; THROMBIN;

EID: 84922631177     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2014.12.026     Document Type: Article

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