A novel method for synthetic vaccine construction based on protein assembly

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Liu, Zhida ^a,b   Zhou, Hang ^a,b   Wang, Wenjun ^a,b   Tan, Wenjie ^c   Fu, Yang Xin ^d   Zhu, Mingzhao ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c BEIJING HOSPITAL   (China)

^d UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN; PROTEIN BINDING; PROTEIN SUBUNIT; RECOMBINANT VACCINE;

AMINO ACID SEQUENCE; BINDING SITE; CHEMISTRY; DRUG DESIGN; IMMUNOLOGY; MOLECULAR GENETICS; PROCEDURES; PROTEIN ENGINEERING; PROTEIN SUBUNIT; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; BINDING SITES; DRUG DESIGN; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN SUBUNITS; PROTEINS; SEQUENCE ANALYSIS, PROTEIN; VACCINES, SYNTHETIC;

EID: 84922624397     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep07266     Document Type: Article

References (32)

1. Baxby, D. Edward Jenner's Inquiry; a bicentenary analysis. Vaccine 17, 301-307 (1999
2. Moyle, P. M. & Toth, I.Modern subunit vaccines: development, components, and research opportunities. ChemMedChem 8, 360-376, doi:10.1002/ cmdc.201200487 (2013
3. Koff, W. C., Gust, I. D. & Plotkin, S. A. Toward a Human Vaccines Project. Nat Immunol 15, 589-592, doi:10.1038/ni.2871 (2014
4. Sette, A. & Rappuoli, R. Reverse vaccinology: developing vaccines in the era of genomics. Immunity 33, 530-541, doi:10.1016/j.immuni.2010.09.017 (2010
5. Zakeri, B, et al. Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin. Proc Natl Acad Sci U S A 109, E690-697, doi:10.1073/pnas.1115485109 (2012
6. Oke, M, et al. The Scottish Structural Proteomics Facility: targets, methods and outputs. J Struct Funct Genomics 11, 167-180, doi:10.1007/s10969-010-9090-y (2010
7. Hagan, R. M. et al.NMRspectroscopic and theoretical analysis of a spontaneously formed Lys-Asp isopeptide bond. Angew Chem Int Ed Engl 49, 8421-8425, doi:10.1002/anie.201004340 (2010
8. Palucka, K., Banchereau, J. &Mellman, I. Designing vaccines based on biology of human dendritic cell subsets. Immunity 33, 464-478, doi:10.1016/ j.immuni.2010.10.007 (2010
9. Banchereau, J. & Steinman, R. M. Dendritic cells and the control of immunity. Nature 392, 245-252, doi:10.1038/32588 (1998
10. Figdor, C. G., de Vries, I. J., Lesterhuis, W. J. & Melief, C. J. Dendritic cell immunotherapy: mapping the way. Nat Med 10, 475-480, doi:10.1038/nm1039 (2004
11. Tacken, P. J., de Vries, I. J., Torensma, R. & Figdor, C. G. Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting. Nat Rev Immunol 7, 790-802, doi:10.1038/nri2173 (2007
12. Villadangos, J. A. & Schnorrer, P. Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo. Nat Rev Immunol 7, 543-555, doi:10.1038/nri2103 (2007
13. Thery, C. & Amigorena, S. The cell biology of antigen presentation in dendritic cells. Curr Opin Immunol 13, 45-51 (2001
14. Shortman, K. & Heath, W. R. The CD81dendritic cell subset. Immunol Rev 234, 18-31, doi:10.1111/j.0105-2896.2009.00870.x (2010
15. Meixlsperger, S, et al. CD1411 dendritic cells produce prominent amounts of IFN-Alpha after dsRNA recognition and can be targeted via DEC-205 in humanized mice. Blood 121, 5034-5044, doi:10.1182/blood-2012-12-473413 (2013
16. Bonifaz, L. C, et al. In vivo targeting of antigens tomaturing dendritic cells via the DEC-205 receptor improves T cell vaccination. J Exp Med 199, 815-824, doi:10.1084/jem.20032220 (2004
17. Johnson, T. S, et al. Inhibition of melanoma growth by targeting of antigen to dendritic cells via an anti-DEC-205 single-chain fragment variable molecule. Clin Cancer Res 14, 8169-8177, doi:10.1158/1078-0432.CCR-08-1474 (2008
18. Nchinda, G, et al. The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells. J Clin Invest 118, 1427-1436, doi:10.1172/JCI34224 (2008
19. Boscardin, S. B, et al. Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses. J Exp Med 203, 599-606, doi:10.1084/jem.20051639 (2006
20. Lahoud, M. H, et al. Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype. J Immunol 187, 842-850, doi:10.4049/jimmunol.1101176 (2011
21. Dhodapkar, M. V, et al. Induction of antigen-specific immunity with a vaccine targeting NY-ESO-1 to the dendritic cell receptor DEC-205. Sci Transl Med 6, 232ra251, doi:10.1126/scitranslmed.3008068 (2014
22. Holbrook, M. R., Shope, R. E. & Barrett, A. D. Use of recombinant E protein domain III-based enzyme-linked immunosorbent assays for differentiation of tick-borne encephalitis serocomplex flaviviruses from mosquito-borne flaviviruses. J Clin Microbiol 42, 4101-4110, doi:10.1128/JCM.42.9.4101-4110.2004 (2004
23. Mandl, C. W., Guirakhoo, F., Holzmann, H., Heinz, F. X. & Kunz, C. Antigenic structure of the flavivirus envelope protein E at the molecular level, using tickborne encephalitis virus as a model. J Virol 63, 564-571 (1989
24. Li, L., Fierer, J. O., Rapoport, T. A. & Howarth, M. Structural analysis and optimization of the covalent association between SpyCatcher and a peptide Tag. J Mol Biol 426, 309-317, doi:10.1016/j.jmb.2013.10.021 (2014
25. Peiris, J. S., Guan, Y. & Yuen, K. Y. Severe acute respiratory syndrome. Nat Med 10, S88-97, doi:10.1038/nm1143 (2004
26. Michaelis, M., Doerr, H. W. & Cinatl, J., Jr. An influenza A H1N1 virus revival -pandemic H1N1/09 virus. Infection 37, 381-389, doi:10.1007/s15010-009-9181-5 (2009
27. Zaki, A. M., van Boheemen, S., Bestebroer, T. M., Osterhaus, A. D. & Fouchier, R. A. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med 367, 1814-1820, doi:10.1056/NEJMoa1211721 (2012
28. Kang, H. J. & Baker, E. N. Intramolecular isopeptide bonds: protein crosslinks built for stress?. Trends Biochem Sci 36, 229-237, doi:10.1016/j.tibs.2010.09.007 (2011
29. Popp, M. W., Antos, J. M., Grotenbreg, G. M., Spooner, E. & Ploegh, H. L. Sortagging: a versatile method for protein labeling. Nat Chem Biol 3, 707-708, doi:10.1038/nchembio.2007.31 (2007
30. Zettler, J., Schutz, V. &Mootz, H. D. The naturally split Npu DnaE intein exhibits an extraordinarily high rate in the protein trans-splicing reaction. FEBS Lett 583, 909-914, doi:10.1016/j.febslet.2009.02.003 (2009
31. Fierer, J. O., Veggiani, G. & Howarth, M. SpyLigase peptide-peptide ligation polymerizes affibodies to enhance magnetic cancer cell capture. Proc Natl Acad Sci U S A 111, E1176-1181, doi:10.1073/pnas.1315776111 (2014
32. Larsen, J. E., Lund, O. & Nielsen, M. Improved method for predicting linear B-cell epitopes. Immunome Res 2, 2, doi:10.1186/1745-7580-2-2 (2006