Omentin-1 levels are reduced by pharmacologic doses of leptin, but remain unaffected by energy deprivation and display no day-night variation

International Journal of Obesity

Volumn 39, Issue 2, 2015, Pages 260-264

  Hamnvik, O P R ^a   Thakkar, B ^a,b   Chamberland, J ^a   Aronis, K ^a   Schneider, B ^a   Mantzoros, C S ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GLYCOSYLATED PROTEIN; INTERLEUKIN 6; METRELEPTIN; OMENTIN 1; PLACEBO; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; UNCLASSIFIED DRUG; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; ITLN1 PROTEIN, HUMAN; LECTIN; LEPTIN; TUMOR NECROSIS FACTOR;

ADIPOSE TISSUE; ADULT; ARTICLE; BARIATRIC SURGERY; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG DOSE INCREASE; ENERGY EXPENDITURE; EX VIVO STUDY; FEMALE; HUMAN; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; WEIGHT REDUCTION; ANALOGS AND DERIVATIVES; BLOOD; DIET RESTRICTION; DOSE RESPONSE; DRUG EFFECTS; ENERGY METABOLISM; METABOLISM; OBESITY;

BARIATRIC SURGERY; CIRCADIAN RHYTHM; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; FASTING; GPI-LINKED PROTEINS; HUMANS; INTERLEUKIN-6; LECTINS; LEPTIN; OBESITY; TUMOR NECROSIS FACTOR-ALPHA; WEIGHT LOSS;

EID: 84922624344     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2014.106     Document Type: Article

References (34)

1. Liu J, Fox CS, Hickson D, Bidulescu A, Carr JJ, Taylor HA. Fatty liver, abdominal visceral fat, and cardiometabolic risk factors: the Jackson Heart Study. Arterioscler Thromb Vasc Biol 2011; 31: 2715-2722.
2. Liu J, Fox CS, Hickson DA, May WD, Hairston KG, Carr JJ et al. Impact of abdominal visceral and subcutaneous adipose tissue on cardiometabolic risk factors: the Jackson Heart Study. J Clin Endocrinol Metab 2010; 95: 5419-5426.
3. Fox CS, Massaro JM, Hoffmann U, Pou KM, Maurovich-Horvat P, Liu CY et al. Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation 2007; 116: 39-48.
4. Schaffler A, Neumeier M, Herfarth H, Furst A, Scholmerich J, Buchler C. Genomic structure of human omentin, a new adipocytokine expressed in omental adipose tissue. Biochim Biophys Acta 2005; 1732: 96-102.
5. Yang RZ, Lee MJ, Hu H, Pray J, Wu HB, Hansen BC et al. Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action. Am J Physiol Endocrinol Metab 2006; 290: E1253-E1261.
6. Tan BK, Adya R, Farhatullah S, Lewandowski KC, O'Hare P, Lehnert H et al. Omentin-1, a novel adipokine, is decreased in overweight insulin-resistant women with polycystic ovary syndrome: ex vivo and in vivo regulation of omentin-1 by insulin and glucose. Diabetes 2008; 57: 801-808.
7. Barth S, Klein P, Horbach T, Dotsch J, Rauh M, Rascher W et al. Expression of neuropeptide Y, omentin and visfatin in visceral and subcutaneous adipose tissues in humans: relation to endocrine and clinical parameters. Obesity Facts 2010; 3: 245-251.
8. Auguet T, Quintero Y, Riesco D, Morancho B, Terra X, Crescenti A et al. New adipokines vaspin and omentin. Circulating levels and gene expression in adipose tissue from morbidly obese women. BMC Med Genet 2011; 12: 60.
9. Fain JN, Sacks HS, Buehrer B, Bahouth SW, Garrett E, Wolf RY et al. Identification of omentin mRNA in human epicardial adipose tissue: comparison to omentin in subcutaneous, internal mammary artery periadventitial and visceral abdominal depots. Int J Obes 2008; 32: 810-815.
10. de Souza Batista CM, Yang RZ, Lee MJ, Glynn NM, Yu DZ, Pray J et al. Omentin plasma levels and gene expression are decreased in obesity. Diabetes 2007; 56: 1655-1661.
11. Shibata R, Takahashi R, Kataoka Y, Ohashi K, Ikeda N, Kihara S et al. Association of a fat-derived plasma protein omentin with carotid artery intima-media thickness in apparently healthy men. Hypertens Res 2011; 34: 1309-1312.
12. Moreno-Navarrete JM, Ortega F, Castro A, Sabater M, Ricart W, Fernandez-Real JM. Circulating omentin as a novel biomarker of endothelial dysfunction. Obesity 2011; 19: 1552-1559.
13. Moreno-Navarrete JM, Catalan V, Ortega F, Gomez-Ambrosi J, Ricart W, Fruhbeck G et al. Circulating omentin concentration increases after weight loss. Nutr Metab 2010; 7: 27.
14. Saremi A, Asghari M, Ghorbani A. Effects of aerobic training on serum omentin-1 and cardiometabolic risk factors in overweight and obese men. J Sports Sci 2010; 28: 993-998.
15. El-Mesallamy HO, El-Derany MO, Hamdy NM. Serum omentin-1 and chemerin levels are interrelated in patients with Type 2 diabetes mellitus with or without ischaemic heart disease. Diabet Med 2011; 28: 1194-1200.
16. Pan HY, Guo L, Li Q. Changes of serum omentin-1 levels in normal subjects and in patients with impaired glucose regulation and with newly diagnosed and untreated type 2 diabetes. Diabetes Res Clin Pract 2010; 88: 29-33.
17. Choi JH, Rhee EJ, Kim KH, Woo HY, Lee WY, Sung KC. Plasma omentin-1 levels are reduced in non-obese women with normal glucose tolerance and polycystic ovary syndrome. Eur J Endocrinol 2011; 165: 789-796.
18. Liu R, Wang X, Bu P. Omentin-1 is associated with carotid atherosclerosis in patients with metabolic syndrome. Diabetes Res Clin Pract 2011; 93: 21-25.
19. Yan P, Liu D, Long M, Ren Y, Pang J, Li R. Changes of serum omentin levels and relationship between omentin and adiponectin concentrations in type 2 diabetes mellitus. Exp Clin Endocrinol Diabetes 2011; 119: 257-263.
20. Yamawaki H, Tsubaki N, Mukohda M, Okada M, Hara Y. Omentin, a novel adipokine, induces vasodilation in rat isolated blood vessels. Biochem Biophys Res Commun 2010; 393: 668-672.
21. Van de Voorde J, Pauwels B, Boydens C, Decaluwe K. Adipocytokines in relation to cardiovascular disease. Metabolism 2013; 62: 1513-1521.
22. Brunetti L, Orlando G, Ferrante C, Recinella L, Leone S, Chiavaroli A et al. Orexigenic effects of omentin-1 related to decreased CART and CRH gene expression and increased norepinephrine synthesis and release in the hypothalamus. Peptides 2013; 44: 66-74.
23. Brunetti L, Di Nisio C, Recinella L, Chiavaroli A, Leone S, Ferrante C et al. Effects of vaspin, chemerin and omentin-1 on feeding behavior and hypothalamic peptide gene expression in the rat. Peptides 2011; 32: 1866-1871.
24. Kazama K, Usui T, Okada M, Hara Y, Yamawaki H. Omentin plays an antiinflammatory role through inhibition of TNF-alpha-induced superoxide production in vascular smooth muscle cells. Eur J Pharmacol 2012; 686: 116-123.
25. Zhong X, Li X, Liu F, Tan H, Shang D. Omentin inhibits TNF-alpha-induced expression of adhesion molecules in endothelial cells via ERK/NF-kappaB pathway. Biochem Biophys Res Commun 2012; 425: 401-406.
26. Yamawaki H. Vascular effects of novel adipocytokines: focus on vascular contractility and inflammatory responses. Biol Pharm Bull 2011; 34: 307-310.
27. Yamawaki H, Kuramoto J, Kameshima S, Usui T, Okada M, Hara Y. Omentin, a novel adipocytokine inhibits TNF-induced vascular in flammation in human endothelial cells. Biochem Biophys Res Commun 2011; 408: 339-343.
28. Chan JL, Heist K, DePaoli AM, Veldhuis JD, Mantzoros CS. The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men. J Clin Invest 2003; 111: 1409-1421.
29. Kershaw EE, Flier JS. Adipose tissue as an endocrine organ. J Clin Endocrinol Metab 2004; 89: 2548-2556.
30. Montague CT, Prins JB, Sanders L, Digby JE, O'Rahilly S. Depot- and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution. Diabetes 1997; 46: 342-347.
31. Batra A, Okur B, Glauben R, Erben U, Ihbe J, Stroh T et al. Leptin: a critical regulator of CD4+ T-cell polarization in vitro and in vivo. Endocrinology 2010; 151: 56-62.
32. Tan BK, Adya R, Farhatullah S, Chen J, Lehnert H, Randeva HS. Metformin treatment may increase omentin-1 levels in women with polycystic ovary syndrome. Diabetes 2010; 59: 3023-3031.
33. Shaker M, Mashhadani ZI, Mehdi AA. Effect of treatment with metformin on omentin-1, ghrelin and other biochemical, clinical features in PCOS patients. Oman Med J 2010; 25: 289-293.
34. Korner J, Punyanitya M, Taveras C, McMahon DJ, Kim HJ, Inabnet W et al. Sex differences in visceral adipose tissue post-bariatric surgery compared to matched non-surgical controls. Int J Body Compos Res 2008; 6: 93-99.