메뉴 건너뛰기




Volumn 10, Issue 2, 2015, Pages

Interleukin 6 receptor is an independent prognostic factor and a potential therapeutic target of ovarian cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CD11B ANTIGEN; CD14 ANTIGEN; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; PLATINUM COMPLEX; TAXANE DERIVATIVE; TOCILIZUMAB; VASCULOTROPIN A;

EID: 84922614400     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0118080     Document Type: Article
Times cited : (69)

References (33)
  • 1
    • 84859219044 scopus 로고    scopus 로고
    • Inflammation and ovarian cancer
    • PMID: 22349527
    • Maccio A, Madeddu C (2012) Inflammation and ovarian cancer. Cytokine 58: 133-147. doi: 10.1016/j. cyto.2012.01.015 PMID: 22349527
    • (2012) Cytokine , vol.58 , pp. 133-147
    • Maccio, A.1    Madeddu, C.2
  • 3
    • 0028203595 scopus 로고
    • Interleukin-6 level in serum and ascites as a prognostic factor in patients with epithelial ovarian cancer
    • PMID: 8137215
    • Plante M, Rubin SC, Wong GY, Federici MG, Finstad CL, et al. (1994) Interleukin-6 level in serum and ascites as a prognostic factor in patients with epithelial ovarian cancer. Cancer 73: 1882-1888. PMID: 8137215
    • (1994) Cancer , vol.73 , pp. 1882-1888
    • Plante, M.1    Rubin, S.C.2    Wong, G.Y.3    Federici, M.G.4    Finstad, C.L.5
  • 4
    • 0028871101 scopus 로고
    • Prognostic significance of interleukin 6 serum levels in patients with ovarian cancer
    • PMID: 7841052
    • Scambia G, Testa U, Benedetti Panici P, Foti E, Martucci R, et al. (1995) Prognostic significance of interleukin 6 serum levels in patients with ovarian cancer. British journal of cancer 71: 354-356. PMID: 7841052
    • (1995) British Journal of Cancer , vol.71 , pp. 354-356
    • Scambia, G.1    Testa, U.2    Benedetti Panici, P.3    Foti, E.4    Martucci, R.5
  • 7
    • 84865422083 scopus 로고    scopus 로고
    • Interleukin-6 signaling pathway in targeted therapy for cancer
    • PMID: 22651903
    • Guo Y, Xu F, Lu T, Duan Z, Zhang Z (2012) Interleukin-6 signaling pathway in targeted therapy for cancer. Cancer treatment reviews 38: 904-910. doi: 10.1016/j.ctrv.2012.04.007 PMID: 22651903
    • (2012) Cancer Treatment Reviews , vol.38 , pp. 904-910
    • Guo, Y.1    Xu, F.2    Lu, T.3    Duan, Z.4    Zhang, Z.5
  • 8
    • 23644442893 scopus 로고    scopus 로고
    • Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family
    • PMID: 16102523
    • Mihara M, Kasutani K, Okazaki M, Nakamura A, Kawai S, et al. (2005) Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family. International immunopharmacology 5: 1731-1740. PMID: 16102523
    • (2005) International Immunopharmacology , vol.5 , pp. 1731-1740
    • Mihara, M.1    Kasutani, K.2    Okazaki, M.3    Nakamura, A.4    Kawai, S.5
  • 9
    • 69949107746 scopus 로고    scopus 로고
    • Humanized anti-interleukin-6 receptor antibody suppresses tumor angiogenesis and in vivo growth of human oral squamous cell carcinoma
    • PMID: 19706815
    • Shinriki S, Jono H, Ota K, Ueda M, Kudo M, et al. (2009) Humanized anti-interleukin-6 receptor antibody suppresses tumor angiogenesis and in vivo growth of human oral squamous cell carcinoma. Clinical cancer research: an official journal of the American Association for Cancer Research 15: 5426-5434. doi: 10.1158/1078-0432.CCR-09-0287 PMID: 19706815
    • (2009) Clinical Cancer Research: An Official Journal of the American Association for Cancer Research , vol.15 , pp. 5426-5434
    • Shinriki, S.1    Jono, H.2    Ota, K.3    Ueda, M.4    Kudo, M.5
  • 10
    • 27144488346 scopus 로고    scopus 로고
    • Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease
    • PMID: 15998837
    • Nishimoto N, Kanakura Y, Aozasa K, Johkoh T, Nakamura M, et al. (2005) Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease. Blood 106: 2627-2632. PMID: 15998837
    • (2005) Blood , vol.106 , pp. 2627-2632
    • Nishimoto, N.1    Kanakura, Y.2    Aozasa, K.3    Johkoh, T.4    Nakamura, M.5
  • 11
    • 34447300492 scopus 로고    scopus 로고
    • Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): Evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab
    • PMID: 17485422
    • Nishimoto N, Hashimoto J, Miyasaka N, Yamamoto K, Kawai S, et al. (2007) Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab. Annals of the rheumatic diseases 66: 1162-1167. PMID: 17485422
    • (2007) Annals of the Rheumatic Diseases , vol.66 , pp. 1162-1167
    • Nishimoto, N.1    Hashimoto, J.2    Miyasaka, N.3    Yamamoto, K.4    Kawai, S.5
  • 13
    • 0025175532 scopus 로고
    • Constitutive production of interleukin 6 by ovarian cancer cell lines and by primary ovarian tumor cultures
    • PMID: 2208162
    • Watson JM, Sensintaffar JL, Berek JS, Martinez-Maza O (1990) Constitutive production of interleukin 6 by ovarian cancer cell lines and by primary ovarian tumor cultures. Cancer research 50: 6959-6965. PMID: 2208162
    • (1990) Cancer Research , vol.50 , pp. 6959-6965
    • Watson, J.M.1    Sensintaffar, J.L.2    Berek, J.S.3    Martinez-Maza, O.4
  • 15
    • 84875967041 scopus 로고    scopus 로고
    • Minocycline suppresses interleukine-6, its receptor system and signaling pathways and impairs migration, invasion and adhesion capacity of ovarian cancer cells: In vitro and in vivo studies
    • PMID: 23593315
    • Ataie-Kachoie P, Morris DL, Pourgholami MH (2013) Minocycline suppresses interleukine-6, its receptor system and signaling pathways and impairs migration, invasion and adhesion capacity of ovarian cancer cells: in vitro and in vivo studies. PloS one 8: e60817. doi: 10.1371/journal.pone.0060817 PMID: 23593315
    • (2013) PloS One , vol.8 , pp. e60817
    • Ataie-Kachoie, P.1    Morris, D.L.2    Pourgholami, M.H.3
  • 16
    • 34250821793 scopus 로고    scopus 로고
    • Macrophages mediate inflammation-enhanced metastasis of ovarian tumors in mice
    • PMID: 17575137
    • Robinson-Smith TM, Isaacsohn I, Mercer CA, Zhou M, Van Rooijen N, et al. (2007) Macrophages mediate inflammation-enhanced metastasis of ovarian tumors in mice. Cancer research 67: 5708-5716. PMID: 17575137
    • (2007) Cancer Research , vol.67 , pp. 5708-5716
    • Robinson-Smith, T.M.1    Isaacsohn, I.2    Mercer, C.A.3    Zhou, M.4    Van Rooijen, N.5
  • 17
    • 34250327022 scopus 로고    scopus 로고
    • Scavenger receptor-A-targeted leukocyte depletion inhibits peritoneal ovarian tumor progression
    • PMID: 17510407
    • Bak SP, Walters JJ, Takeya M, Conejo-Garcia JR, Berwin BL (2007) Scavenger receptor-A-targeted leukocyte depletion inhibits peritoneal ovarian tumor progression. Cancer research 67: 4783-4789. PMID: 17510407
    • (2007) Cancer Research , vol.67 , pp. 4783-4789
    • Bak, S.P.1    Walters, J.J.2    Takeya, M.3    Conejo-Garcia, J.R.4    Berwin, B.L.5
  • 18
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • PMID: 14708027
    • Pollard JW (2004) Tumour-educated macrophages promote tumour progression and metastasis. Nature reviews Cancer 4: 71-78. PMID: 14708027
    • (2004) Nature Reviews Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 19
    • 65349163532 scopus 로고    scopus 로고
    • Detection of M2 macrophages and colony-stimulating factor 1 expression in serous and mucinous ovarian epithelial tumors
    • PMID: 19432671
    • Kawamura K, Komohara Y, Takaishi K, Katabuchi H, TakeyaM (2009) Detection of M2 macrophages and colony-stimulating factor 1 expression in serous and mucinous ovarian epithelial tumors. Pathology international 59: 300-305. doi: 10.1111/j.1440-1827.2009.02369.x PMID: 19432671
    • (2009) Pathology International , vol.59 , pp. 300-305
    • Kawamura, K.1    Komohara, Y.2    Takaishi, K.3    Katabuchi, H.4    Takeya, M.5
  • 20
    • 34447345507 scopus 로고    scopus 로고
    • Primary culture of ovarian surface epithelial cells and ascites-derived ovarian cancer cells from patients
    • PMID: 17406520
    • Shepherd TG, Theriault BL, Campbell EJ, NachtigalMW(2006) Primary culture of ovarian surface epithelial cells and ascites-derived ovarian cancer cells from patients. Nature protocols 1: 2643-2649. PMID: 17406520
    • (2006) Nature Protocols , vol.1 , pp. 2643-2649
    • Shepherd, T.G.1    Theriault, B.L.2    Campbell, E.J.3    Nachtigal, M.W.4
  • 21
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T))
    • PMID: 11846609
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408. PMID: 11846609
    • (2001) Method. Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 22
    • 0027369308 scopus 로고
    • Serum and ascitic fluid levels of interleukin-1, interleukin-6, and tumor necrosis factor-alpha in patients with ovarian epithelial cancer
    • PMID: 8402460
    • Moradi MM, Carson LF, Weinberg B, Haney AF, Twiggs LB, et al. (1993) Serum and ascitic fluid levels of interleukin-1, interleukin-6, and tumor necrosis factor-alpha in patients with ovarian epithelial cancer. Cancer 72: 2433-2440. PMID: 8402460
    • (1993) Cancer , vol.72 , pp. 2433-2440
    • Moradi, M.M.1    Carson, L.F.2    Weinberg, B.3    Haney, A.F.4    Twiggs, L.B.5
  • 23
    • 84862304990 scopus 로고    scopus 로고
    • Interleukin-6 signaling regulates anchorage-independent growth, proliferation, adhesion and invasion in human ovarian cancer cells
    • PMID: 22595649
    • Wang Y, Li L, Guo X, Jin X, Sun W, et al. (2012) Interleukin-6 signaling regulates anchorage-independent growth, proliferation, adhesion and invasion in human ovarian cancer cells. Cytokine 59: 228-236. doi: 10.1016/j.cyto.2012.04.020 PMID: 22595649
    • (2012) Cytokine , vol.59 , pp. 228-236
    • Wang, Y.1    Li, L.2    Guo, X.3    Jin, X.4    Sun, W.5
  • 24
    • 63049104211 scopus 로고    scopus 로고
    • Microenvironmental regulation of metastasis
    • PMID: 19279573
    • Joyce JA, Pollard JW (2009) Microenvironmental regulation of metastasis. Nature reviews Cancer 9: 239-252. doi: 10.1038/nrc2618 PMID: 19279573
    • (2009) Nature Reviews Cancer , vol.9 , pp. 239-252
    • Joyce, J.A.1    Pollard, J.W.2
  • 27
    • 84885951882 scopus 로고    scopus 로고
    • Mixed-polarization phenotype of ascites-associated macrophages in human ovarian carcinoma: Correlation of CD163 expression, cytokine levels and early relapse
    • PMID: 23784932
    • Reinartz S, Schumann T, Finkernagel F, Wortmann A, Jansen JM, et al. (2014) Mixed-polarization phenotype of ascites-associated macrophages in human ovarian carcinoma: correlation of CD163 expression, cytokine levels and early relapse. International journal of cancer Journal international du cancer 134: 32-42. doi: 10.1002/ijc.28335 PMID: 23784932
    • (2014) International Journal of Cancer Journal International Du Cancer , vol.134 , pp. 32-42
    • Reinartz, S.1    Schumann, T.2    Finkernagel, F.3    Wortmann, A.4    Jansen, J.M.5
  • 28
    • 58149218143 scopus 로고    scopus 로고
    • Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas
    • PMID: 19088723
    • Colomiere M, Ward AC, Riley C, Trenerry MK, Cameron-Smith D, et al. (2009) Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas. British journal of cancer 100: 134-144. doi: 10.1038/sj.bjc.6604794 PMID: 19088723
    • (2009) British Journal of Cancer , vol.100 , pp. 134-144
    • Colomiere, M.1    Ward, A.C.2    Riley, C.3    Trenerry, M.K.4    Cameron-Smith, D.5
  • 30
    • 84876117522 scopus 로고    scopus 로고
    • Humanised antihuman IL-6R antibody with interferon inhibits renal cell carcinoma cell growth in vitro and in vivo through suppressed SOCS3 expression
    • PMID: 23274199
    • Oguro T, Ishibashi K, Sugino T, Hashimoto K, Tomita S, et al. (2013) Humanised antihuman IL-6R antibody with interferon inhibits renal cell carcinoma cell growth in vitro and in vivo through suppressed SOCS3 expression. European journal of cancer 49: 1715-1724. doi: 10.1016/j.ejca.2012.11.038 PMID: 23274199
    • (2013) European Journal of Cancer , vol.49 , pp. 1715-1724
    • Oguro, T.1    Ishibashi, K.2    Sugino, T.3    Hashimoto, K.4    Tomita, S.5
  • 32
    • 84873619713 scopus 로고    scopus 로고
    • Targeted anti-vascular therapies for ovarian cancer: Current evidence
    • PMID: 23385789
    • Hall M, Gourley C, McNeish I, Ledermann J, Gore M, et al. (2013) Targeted anti-vascular therapies for ovarian cancer: current evidence. British journal of cancer 108: 250-258. doi: 10.1038/bjc.2012.541 PMID: 23385789
    • (2013) British Journal of Cancer , vol.108 , pp. 250-258
    • Hall, M.1    Gourley, C.2    McNeish, I.3    Ledermann, J.4    Gore, M.5
  • 33
    • 84876998346 scopus 로고    scopus 로고
    • Chemotherapy alters monocyte differentiation to favor generation of cancer-supporting M2 macrophages in the tumor microenvironment
    • PMID: 23436796
    • Dijkgraaf EM, Heusinkveld M, Tummers B, Vogelpoel LT, Goedemans R, et al. (2013) Chemotherapy alters monocyte differentiation to favor generation of cancer-supporting M2 macrophages in the tumor microenvironment. Cancer research 73: 2480-2492. doi: 10.1158/0008-5472.CAN-12-3542 PMID: 23436796
    • (2013) Cancer Research , vol.73 , pp. 2480-2492
    • Dijkgraaf, E.M.1    Heusinkveld, M.2    Tummers, B.3    Vogelpoel, L.T.4    Goedemans, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.