메뉴 건너뛰기




Volumn 95, Issue 4, 2015, Pages 590-604

Vibrio choleraeMARTX toxin heterologous translocation of beta-lactamase and roles of individual effector domains on cytoskeleton dynamics

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; BACTERIAL TOXIN; BETA LACTAMASE; MULTIFUNCTIONAL AUTOPROCESSING REPEATS IN TOXIN; PROTEIN CDC42; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; RTXA PROTEIN, VIBRIO CHOLERAE;

EID: 84922602285     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/mmi.12879     Document Type: Article
Times cited : (37)

References (49)
  • 1
    • 84922667784 scopus 로고    scopus 로고
    • Identification of essential residues in the Rho-inactivation domain of the multifunctional autoprocessing RTX toxin of Vibrio cholerae and its interplay with other effectors
    • ProQuest, UMI Dissertations Publishing: Ann Arbor, MI.
    • Ahrens, S. (2014) Identification of essential residues in the Rho-inactivation domain of the multifunctional autoprocessing RTX toxin of Vibrio cholerae and its interplay with other effectors. ProQuest, UMI Dissertations Publishing: Ann Arbor, MI., pp. 144.
    • (2014) , pp. 144
    • Ahrens, S.1
  • 2
    • 84872325245 scopus 로고    scopus 로고
    • Identification of a His-Asp-Cys catalytic triad essential for function of the Rho inactivation domain (RID) of Vibrio cholerae MARTX toxin
    • Ahrens, S., Geissler, B., and Satchell, K.J. (2013) Identification of a His-Asp-Cys catalytic triad essential for function of the Rho inactivation domain (RID) of Vibrio cholerae MARTX toxin. J Biol Chem 288: 1397-1408.
    • (2013) J Biol Chem , vol.288 , pp. 1397-1408
    • Ahrens, S.1    Geissler, B.2    Satchell, K.J.3
  • 3
    • 79953298400 scopus 로고    scopus 로고
    • Identification of V.cholerae type three secretion system effector proteins
    • Alam, A., Miller, K.A., Chaand, M., Butler, J.S., and Dziejman, M. (2011) Identification of V.cholerae type three secretion system effector proteins. Infect Immun 79: 1728-1740.
    • (2011) Infect Immun , vol.79 , pp. 1728-1740
    • Alam, A.1    Miller, K.A.2    Chaand, M.3    Butler, J.S.4    Dziejman, M.5
  • 4
    • 84922605535 scopus 로고    scopus 로고
    • Cytotoxicity of the Vibrio vulnificus MARTX toxin Effector DUF5 is linked to the C2A Subdomain
    • Antic, I., Biancucci, M., and Satchell, K.J. (2014) Cytotoxicity of the Vibrio vulnificus MARTX toxin Effector DUF5 is linked to the C2A Subdomain. Proteins 82: 2643-2656.
    • (2014) Proteins , vol.82 , pp. 2643-2656
    • Antic, I.1    Biancucci, M.2    Satchell, K.J.3
  • 5
    • 9244243093 scopus 로고    scopus 로고
    • Vibrio cholerae strains with mutations in an atypical type I secretion system accumulate RTX toxin intracellularly
    • Boardman, B.K., and Satchell, K.J. (2004) Vibrio cholerae strains with mutations in an atypical type I secretion system accumulate RTX toxin intracellularly. J Bacteriol 186: 8137-8143.
    • (2004) J Bacteriol , vol.186 , pp. 8137-8143
    • Boardman, B.K.1    Satchell, K.J.2
  • 6
    • 84869842318 scopus 로고    scopus 로고
    • Unique substrates secreted by the type VI secretion system of Francisella tularensis during intramacrophage infection
    • Broms, J.E., Meyer, L., Sun, K., Lavander, M., and Sjostedt, A. (2012) Unique substrates secreted by the type VI secretion system of Francisella tularensis during intramacrophage infection. PLoS ONE 7: e50473.
    • (2012) PLoS ONE , vol.7 , pp. e50473
    • Broms, J.E.1    Meyer, L.2    Sun, K.3    Lavander, M.4    Sjostedt, A.5
  • 7
    • 3843065509 scopus 로고    scopus 로고
    • Identification of the secretion and translocation domain of the enteropathogenic and enterohemorrhagic Escherichia coli effector Cif, using TEM-1 beta-lactamase as a new fluorescence-based reporter
    • Charpentier, X., and Oswald, E. (2004) Identification of the secretion and translocation domain of the enteropathogenic and enterohemorrhagic Escherichia coli effector Cif, using TEM-1 beta-lactamase as a new fluorescence-based reporter. J Bacteriol 186: 5486-5495.
    • (2004) J Bacteriol , vol.186 , pp. 5486-5495
    • Charpentier, X.1    Oswald, E.2
  • 8
    • 33845951878 scopus 로고    scopus 로고
    • The actin cross-linking domain of the Vibrio cholerae RTX toxin directly catalyzes the covalent cross-linking of actin
    • Cordero, C.L., Kudryashov, D.S., Reisler, E., and Satchell, K.J. (2006) The actin cross-linking domain of the Vibrio cholerae RTX toxin directly catalyzes the covalent cross-linking of actin. J Biol Chem 281: 32366-32374.
    • (2006) J Biol Chem , vol.281 , pp. 32366-32374
    • Cordero, C.L.1    Kudryashov, D.S.2    Reisler, E.3    Satchell, K.J.4
  • 9
    • 0000696532 scopus 로고
    • Cloning and expression of the gene for bacteriophage T7 RNA polymerase
    • Davanloo, P., Rosenberg, A.H., Dunn, J.J., and Studier, F.W. (1984) Cloning and expression of the gene for bacteriophage T7 RNA polymerase. Proc Natl Acad Sci USA 81: 2035-2039.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 2035-2039
    • Davanloo, P.1    Rosenberg, A.H.2    Dunn, J.J.3    Studier, F.W.4
  • 10
    • 84880053654 scopus 로고    scopus 로고
    • Analysis of Vibrio cholerae genome sequences reveals unique rtxA variants in environmental strains and an rtxA-null mutation in recent altered El Tor isolates
    • Dolores, J., and Satchell, K.J. (2013) Analysis of Vibrio cholerae genome sequences reveals unique rtxA variants in environmental strains and an rtxA-null mutation in recent altered El Tor isolates. mBio 4: e00624.
    • (2013) mBio , vol.4 , pp. e00624
    • Dolores, J.1    Satchell, K.J.2
  • 11
    • 77957667396 scopus 로고    scopus 로고
    • Inositol hexakisphosphate-induced autoprocessing of large bacterial protein toxins
    • Egerer, M., and Satchell, K.J. (2010) Inositol hexakisphosphate-induced autoprocessing of large bacterial protein toxins. PLoS Pathog 6: e1000942.
    • (2010) PLoS Pathog , vol.6 , pp. e1000942
    • Egerer, M.1    Satchell, K.J.2
  • 12
    • 0034676002 scopus 로고    scopus 로고
    • In vivo covalent crosslinking of actin by the RTX toxin of Vibrio cholerae
    • Fullner, K.J., and Mekalanos, J.J. (2000) In vivo covalent crosslinking of actin by the RTX toxin of Vibrio cholerae. EMBO J 19: 5315-5323.
    • (2000) EMBO J , vol.19 , pp. 5315-5323
    • Fullner, K.J.1    Mekalanos, J.J.2
  • 13
    • 0034819990 scopus 로고    scopus 로고
    • Vibrio cholerae-induced cellular responses of polarized T84 intestinal epithelial cells dependent of production of cholera toxin and the RTX toxin
    • Fullner, K.J., Lencer, W.I., and Mekalanos, J.J. (2001) Vibrio cholerae-induced cellular responses of polarized T84 intestinal epithelial cells dependent of production of cholera toxin and the RTX toxin. Infect Immun 69: 6310-6317.
    • (2001) Infect Immun , vol.69 , pp. 6310-6317
    • Fullner, K.J.1    Lencer, W.I.2    Mekalanos, J.J.3
  • 14
    • 0037013938 scopus 로고    scopus 로고
    • The contribution of accessory toxins of Vibrio cholerae O1 El Tor to the proinflammatory response in a murine pulmonary cholera model
    • Fullner, K.J., Boucher, J.C., Hanes, M.A., Haines, G.K., 3rd, Meehan, B.M., Walchle, C., etal. (2002) The contribution of accessory toxins of Vibrio cholerae O1 El Tor to the proinflammatory response in a murine pulmonary cholera model. J Exp Med 195: 1455-1462.
    • (2002) J Exp Med , vol.195 , pp. 1455-1462
    • Fullner, K.J.1    Boucher, J.C.2    Hanes, M.A.3    Haines, G.K.4    Meehan, B.M.5    Walchle, C.6
  • 15
    • 70350179458 scopus 로고    scopus 로고
    • Genetic determination of essential residues of the Vibrio cholerae actin cross-linking domain reveals functional similarity with glutamine synthetases
    • Geissler, B., Bonebrake, A., Sheahan, K.L., Walker, M.E., and Satchell, K.J. (2009) Genetic determination of essential residues of the Vibrio cholerae actin cross-linking domain reveals functional similarity with glutamine synthetases. Mol Microbiol 73: 858-868.
    • (2009) Mol Microbiol , vol.73 , pp. 858-868
    • Geissler, B.1    Bonebrake, A.2    Sheahan, K.L.3    Walker, M.E.4    Satchell, K.J.5
  • 16
    • 77950449027 scopus 로고    scopus 로고
    • Identification of a conserved membrane localization domain within numerous large bacterial protein toxins
    • Geissler, B., Tungekar, R., and Satchell, K.J. (2010) Identification of a conserved membrane localization domain within numerous large bacterial protein toxins. Proc Natl Acad Sci USA 107: 5581-5586.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 5581-5586
    • Geissler, B.1    Tungekar, R.2    Satchell, K.J.3
  • 17
    • 70949086347 scopus 로고    scopus 로고
    • Anthrax toxin uptake by primary immune cells as determined with a lethal factor-beta-lactamase fusion protein
    • Hu, H., and Leppla, S.H. (2009) Anthrax toxin uptake by primary immune cells as determined with a lethal factor-beta-lactamase fusion protein. PLoS ONE 4: e7946.
    • (2009) PLoS ONE , vol.4 , pp. e7946
    • Hu, H.1    Leppla, S.H.2
  • 18
    • 3943108216 scopus 로고    scopus 로고
    • Structure and function of TolC: the bacterial exit duct for proteins and drugs
    • Koronakis, V., Eswaran, J., and Hughes, C. (2004) Structure and function of TolC: the bacterial exit duct for proteins and drugs. Annu Rev Biochem 73: 467-489.
    • (2004) Annu Rev Biochem , vol.73 , pp. 467-489
    • Koronakis, V.1    Eswaran, J.2    Hughes, C.3
  • 19
    • 57449094208 scopus 로고    scopus 로고
    • Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin
    • Kudryashov, D.S., Durer, Z.A., Ytterberg, A.J., Sawaya, M.R., Pashkov, I., Prochazkova, K., etal. (2008) Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin. Proc Natl Acad Sci USA 105: 18537-18542.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 18537-18542
    • Kudryashov, D.S.1    Durer, Z.A.2    Ytterberg, A.J.3    Sawaya, M.R.4    Pashkov, I.5    Prochazkova, K.6
  • 20
    • 84866667082 scopus 로고    scopus 로고
    • Glutamyl phosphate is an activated intermediate in actin crosslinking by actin crosslinking domain (ACD) toxin
    • Kudryashova, E., Kalda, C., and Kudryashov, D.S. (2012) Glutamyl phosphate is an activated intermediate in actin crosslinking by actin crosslinking domain (ACD) toxin. PLoS ONE 7: e45721.
    • (2012) PLoS ONE , vol.7 , pp. e45721
    • Kudryashova, E.1    Kalda, C.2    Kudryashov, D.S.3
  • 21
    • 84901406586 scopus 로고    scopus 로고
    • Thermodynamic properties of the effector domains of MARTX toxins suggest their unfolding for translocation across the host membrane
    • Kudryashova, E., Heisler, D., Zywiec, A., and Kudryashov, D.S. (2014) Thermodynamic properties of the effector domains of MARTX toxins suggest their unfolding for translocation across the host membrane. Mol Microbiol 92: 1056-1071.
    • (2014) Mol Microbiol , vol.92 , pp. 1056-1071
    • Kudryashova, E.1    Heisler, D.2    Zywiec, A.3    Kudryashov, D.S.4
  • 22
    • 84856373967 scopus 로고    scopus 로고
    • An rhs gene of Pseudomonas aeruginosa encodes a virulence protein that activates the inflammasome
    • Kung, V.L., Khare, S., Stehlik, C., Bacon, E.M., Hughes, A.J., and Hauser, A.R. (2012) An rhs gene of Pseudomonas aeruginosa encodes a virulence protein that activates the inflammasome. Proc Natl Acad Sci USA 109: 1275-1280.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 1275-1280
    • Kung, V.L.1    Khare, S.2    Stehlik, C.3    Bacon, E.M.4    Hughes, A.J.5    Hauser, A.R.6
  • 23
    • 79952146186 scopus 로고    scopus 로고
    • Vibrio vulnificus Proc Natl Acad Sci USA gene recombination generates toxin variants with altered potency during intestinal infection
    • Kwak, J.S., Jeong, H.G., and Satchell, K.J. (2011) Vibrio vulnificus Proc Natl Acad Sci USA gene recombination generates toxin variants with altered potency during intestinal infection. Proc Natl Acad Sci USA 108: 1645-1650.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 1645-1650
    • Kwak, J.S.1    Jeong, H.G.2    Satchell, K.J.3
  • 24
    • 0033514473 scopus 로고    scopus 로고
    • Identification of a Vibrio cholerae RTX toxin gene cluster that is tightly linked to the cholera toxin prophage
    • Lin, W., Fullner, K.J., Clayton, R., Sexton, J.A., Rogers, M.B., Calia, K.E., etal. (1999) Identification of a Vibrio cholerae RTX toxin gene cluster that is tightly linked to the cholera toxin prophage. Proc Natl Acad Sci USA 96: 1071-1076.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 1071-1076
    • Lin, W.1    Fullner, K.J.2    Clayton, R.3    Sexton, J.A.4    Rogers, M.B.5    Calia, K.E.6
  • 25
    • 61849114089 scopus 로고    scopus 로고
    • Translocation of a Vibrio cholerae type VI secretion effector requires bacterial endocytosis by host cells
    • Ma, A.T., McAuley, S., Pukatzki, S., and Mekalanos, J.J. (2009) Translocation of a Vibrio cholerae type VI secretion effector requires bacterial endocytosis by host cells. Cell Host Microbe 5: 234-243.
    • (2009) Cell Host Microbe , vol.5 , pp. 234-243
    • Ma, A.T.1    McAuley, S.2    Pukatzki, S.3    Mekalanos, J.J.4
  • 27
    • 0022445324 scopus 로고
    • Secretion of beta-lactamase into the periplasm of Escherichia coli: evidence for a distinct release step associated with a conformational change
    • Minsky, A., Summers, R.G., and Knowles, J.R. (1986) Secretion of beta-lactamase into the periplasm of Escherichia coli: evidence for a distinct release step associated with a conformational change. Proc Natl Acad Sci USA 83: 4180-4184.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 4180-4184
    • Minsky, A.1    Summers, R.G.2    Knowles, J.R.3
  • 28
    • 34848891814 scopus 로고    scopus 로고
    • Prolonged colonization of mice by Vibrio cholerae El Tor O1 depends on accessory toxins
    • Olivier, V., Salzman, N.H., and Satchell, K.J. (2007) Prolonged colonization of mice by Vibrio cholerae El Tor O1 depends on accessory toxins. Infect Immun 75: 5043-5051.
    • (2007) Infect Immun , vol.75 , pp. 5043-5051
    • Olivier, V.1    Salzman, N.H.2    Satchell, K.J.3
  • 29
    • 70350220388 scopus 로고    scopus 로고
    • Successful small intestine colonization of adult mice by Vibrio cholerae requires ketamine anesthesia and accessory toxins
    • Olivier, V., Queen, J., and Satchell, K.J. (2009) Successful small intestine colonization of adult mice by Vibrio cholerae requires ketamine anesthesia and accessory toxins. PLoS ONE 4: e7352.
    • (2009) PLoS ONE , vol.4 , pp. e7352
    • Olivier, V.1    Queen, J.2    Satchell, K.J.3
  • 30
    • 1942487190 scopus 로고    scopus 로고
    • Improvement of pCVD442, a suicide plasmid for gene allele exchange in bacteria
    • Philippe, N., Alcaraz, J.P., Coursange, E., Geiselmann, J., and Schneider, D. (2004) Improvement of pCVD442, a suicide plasmid for gene allele exchange in bacteria. Plasmid 51: 246-255.
    • (2004) Plasmid , vol.51 , pp. 246-255
    • Philippe, N.1    Alcaraz, J.P.2    Coursange, E.3    Geiselmann, J.4    Schneider, D.5
  • 31
    • 59749095481 scopus 로고    scopus 로고
    • Sec- and Tat-dependent translocation of beta-lactamases across the Escherichia coli inner membrane
    • Pradel, N., Delmas, J., Wu, L.F., Santini, C.L., and Bonnet, R. (2009) Sec- and Tat-dependent translocation of beta-lactamases across the Escherichia coli inner membrane. Antimicrob Agents Chemother 53: 242-248.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 242-248
    • Pradel, N.1    Delmas, J.2    Wu, L.F.3    Santini, C.L.4    Bonnet, R.5
  • 32
    • 53049108644 scopus 로고    scopus 로고
    • Structure-function analysis of inositol hexakisphosphate-induced autoprocessing of the Vibrio cholerae multifunctional autoprocessing RTX toxin
    • Prochazkova, K., and Satchell, K.J. (2008) Structure-function analysis of inositol hexakisphosphate-induced autoprocessing of the Vibrio cholerae multifunctional autoprocessing RTX toxin. J Biol Chem 283: 23656-23664.
    • (2008) J Biol Chem , vol.283 , pp. 23656-23664
    • Prochazkova, K.1    Satchell, K.J.2
  • 33
    • 70350351548 scopus 로고    scopus 로고
    • Structural and molecular mechanism for autoprocessing of MARTX Toxin of Vibrio cholerae at multiple sites
    • Prochazkova, K., Shuvalova, L.A., Minasov, G., Voburka, Z., Anderson, W.F., and Satchell, K.J. (2009) Structural and molecular mechanism for autoprocessing of MARTX Toxin of Vibrio cholerae at multiple sites. J Biol Chem 284: 26557-26568.
    • (2009) J Biol Chem , vol.284 , pp. 26557-26568
    • Prochazkova, K.1    Shuvalova, L.A.2    Minasov, G.3    Voburka, Z.4    Anderson, W.F.5    Satchell, K.J.6
  • 34
    • 84864808706 scopus 로고    scopus 로고
    • Neutrophils Are essential for containment of Vibrio cholerae to the intestine during the proinflammatory phase of infection
    • Queen, J., and Satchell, K.J. (2012) Neutrophils Are essential for containment of Vibrio cholerae to the intestine during the proinflammatory phase of infection. Infect Immun 80: 2905-2913.
    • (2012) Infect Immun , vol.80 , pp. 2905-2913
    • Queen, J.1    Satchell, K.J.2
  • 35
    • 84884238469 scopus 로고    scopus 로고
    • Promotion of colonization and virulence by cholera toxin is dependent on neutrophils
    • Queen, J., and Satchell, K.J. (2013) Promotion of colonization and virulence by cholera toxin is dependent on neutrophils. Infect Immun 81: 3338-3345.
    • (2013) Infect Immun , vol.81 , pp. 3338-3345
    • Queen, J.1    Satchell, K.J.2
  • 36
    • 79551476590 scopus 로고    scopus 로고
    • Domain organization and evolution of multifunctional autoprocessing repeats-in-toxin (MARTX) toxin in Vibrio vulnificus
    • Roig, F.J., Gonzalez-Candelas, F., and Amaro, C. (2011) Domain organization and evolution of multifunctional autoprocessing repeats-in-toxin (MARTX) toxin in Vibrio vulnificus. Appl Environ Microbiol 77: 657-668.
    • (2011) Appl Environ Microbiol , vol.77 , pp. 657-668
    • Roig, F.J.1    Gonzalez-Candelas, F.2    Amaro, C.3
  • 37
    • 84904062548 scopus 로고    scopus 로고
    • TNF and MAP kinase signalling pathways
    • Sabio, G., and Davis, R.J. (2014) TNF and MAP kinase signalling pathways. Semin Immunol 26: 237-245.
    • (2014) Semin Immunol , vol.26 , pp. 237-245
    • Sabio, G.1    Davis, R.J.2
  • 38
    • 35648975533 scopus 로고    scopus 로고
    • MARTX: multifunctional-Autoprocessing RTX Toxins
    • Satchell, K.J. (2007) MARTX: multifunctional-Autoprocessing RTX Toxins. Infect Immun 75: 5079-5084.
    • (2007) Infect Immun , vol.75 , pp. 5079-5084
    • Satchell, K.J.1
  • 39
    • 79952149238 scopus 로고    scopus 로고
    • Actin crosslinking toxins of Gram-negative bacteria
    • Satchell, K.J. (2009) Actin crosslinking toxins of Gram-negative bacteria. Toxins 1: 123-133.
    • (2009) Toxins , vol.1 , pp. 123-133
    • Satchell, K.J.1
  • 40
    • 80053286819 scopus 로고    scopus 로고
    • Structure and function of MARTX toxins and other large repetitive RTX proteins
    • Satchell, K.J. (2011) Structure and function of MARTX toxins and other large repetitive RTX proteins. Annu Rev Microbiol 65: 71-90.
    • (2011) Annu Rev Microbiol , vol.65 , pp. 71-90
    • Satchell, K.J.1
  • 41
    • 34047255098 scopus 로고    scopus 로고
    • Inactivation of small Rho GTPases by the multifunctional RTX toxin from Vibrio cholerae
    • Sheahan, K.L., and Satchell, K.J. (2007) Inactivation of small Rho GTPases by the multifunctional RTX toxin from Vibrio cholerae. Cell Microbiol 9: 1324-1335.
    • (2007) Cell Microbiol , vol.9 , pp. 1324-1335
    • Sheahan, K.L.1    Satchell, K.J.2
  • 42
    • 3042750470 scopus 로고    scopus 로고
    • Identification of a domain within the multifunctional Vibrio cholerae RTX toxin that covalently cross-links actin
    • Sheahan, K.L., Cordero, C.L., and Satchell, K.J. (2004) Identification of a domain within the multifunctional Vibrio cholerae RTX toxin that covalently cross-links actin. Proc Natl Acad Sci USA 101: 9798-9803.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 9798-9803
    • Sheahan, K.L.1    Cordero, C.L.2    Satchell, K.J.3
  • 43
    • 34249058418 scopus 로고    scopus 로고
    • Autoprocessing of the Vibrio cholerae RTX toxin by the cysteine protease domain
    • Sheahan, K.L., Cordero, C.L., and Satchell, K.J. (2007) Autoprocessing of the Vibrio cholerae RTX toxin by the cysteine protease domain. EMBO J 26: 2552-2561.
    • (2007) EMBO J , vol.26 , pp. 2552-2561
    • Sheahan, K.L.1    Cordero, C.L.2    Satchell, K.J.3
  • 44
    • 67650290548 scopus 로고    scopus 로고
    • Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin
    • Shen, A., Lupardus, P.J., Albrow, V.E., Guzzetta, A., Powers, J.C., Garcia, K.C., and Bogyo, M. (2009) Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin. Nat Chem Biol 5: 469-478.
    • (2009) Nat Chem Biol , vol.5 , pp. 469-478
    • Shen, A.1    Lupardus, P.J.2    Albrow, V.E.3    Guzzetta, A.4    Powers, J.C.5    Garcia, K.C.6    Bogyo, M.7
  • 45
    • 0029145073 scopus 로고
    • Rho family members: activators of MAP kinase cascades
    • Vojtek, A.B., and Cooper, J.A. (1995) Rho family members: activators of MAP kinase cascades. Cell 82: 527-529.
    • (1995) Cell , vol.82 , pp. 527-529
    • Vojtek, A.B.1    Cooper, J.A.2
  • 46
    • 77958133862 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE
    • Vossenkamper, A., Marches, O., Fairclough, P.D., Warnes, G., Stagg, A.J., Lindsay, J.O., etal. (2010) Inhibition of NF-kappaB signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. J Immunol 185: 4118-4127.
    • (2010) J Immunol , vol.185 , pp. 4118-4127
    • Vossenkamper, A.1    Marches, O.2    Fairclough, P.D.3    Warnes, G.4    Stagg, A.J.5    Lindsay, J.O.6
  • 47
    • 84898907292 scopus 로고    scopus 로고
    • Vibrio vulnificus biotype 3 multifunctional autoprocessing RTX toxin is an adenylate cyclase toxin essential for virulence in mice
    • Ziolo, K.J., Jeong, H.G., Kwak, J.S., Yang, S., Lavker, R.M., and Satchell, K.J. (2014) Vibrio vulnificus biotype 3 multifunctional autoprocessing RTX toxin is an adenylate cyclase toxin essential for virulence in mice. Infect Immun 82: 2148-2157.
    • (2014) Infect Immun , vol.82 , pp. 2148-2157
    • Ziolo, K.J.1    Jeong, H.G.2    Kwak, J.S.3    Yang, S.4    Lavker, R.M.5    Satchell, K.J.6
  • 48
    • 0032472195 scopus 로고    scopus 로고
    • Quantitation of transcription and clonal selection of single living cells with beta-lactamase as reporter
    • Zlokarnik, G., Negulescu, P.A., Knapp, T.E., Mere, L., Burres, N., Feng, L., etal. (1998) Quantitation of transcription and clonal selection of single living cells with beta-lactamase as reporter. Science 279: 84-88.
    • (1998) Science , vol.279 , pp. 84-88
    • Zlokarnik, G.1    Negulescu, P.A.2    Knapp, T.E.3    Mere, L.4    Burres, N.5    Feng, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.