An extracorporeal artificial placenta supports extremely premature lambs for 1 week

Journal of Pediatric Surgery

Volumn 50, Issue 1, 2015, Pages 44-49

  Bryner, Benjamin ^a   Gray, Brian ^a   Perkins, Elena ^a   Davis, Ryan ^a   Hoffman, Hayley ^a   Barks, John ^a   Owens, Gabe ^a   Bocks, Martin ^a   Rojas Peña, Alvaro ^a   Hirschl, Ronald ^a   Bartlett, Robert ^a   Mychaliska, George ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Artificial placenta; Extracorporeal life support (ECLS); Extracorporeal membrane oxygenation (ECMO); Lung development; Prematurity

Indexed keywords

DIAZEPAM; HEMOGLOBIN; HEPARIN; HYPERTENSIVE FACTOR; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; STEROID; SURFACTANT; LUNG SURFACTANT;

AIRWAY PRESSURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; ARTIFICIAL ORGAN; ARTIFICIAL PLACENTA; ARTIFICIAL VENTILATION; ASCITES; BLOOD GAS ANALYSIS; CAUSE OF DEATH; CONTROLLED STUDY; GAS EXCHANGE; HEART TAMPONADE; HEMOGLOBIN BLOOD LEVEL; HYPERCAPNIA; HYPOXIA; INTUBATION; LAMB; NEWBORN CARE; NONHUMAN; OXYGENATION; PARENTERAL NUTRITION; PREMATURITY; PRIORITY JOURNAL; SURVIVAL; TRANSTHORACIC ECHOCARDIOGRAPHY; ANIMAL; EXTRACORPOREAL OXYGENATION; FEMALE; HEMODYNAMICS; HIGH FREQUENCY VENTILATION; HUMAN; INFANT, PREMATURE, DISEASES; NEWBORN; PATHOPHYSIOLOGY; PLACENTA; PREGNANCY; PROCEDURES; RESPIRATORY INSUFFICIENCY; SHEEP;

ANIMALS; ANIMALS, NEWBORN; ARTIFICIAL ORGANS; BLOOD GAS ANALYSIS; EXTRACORPOREAL MEMBRANE OXYGENATION; FEMALE; HEMODYNAMICS; HIGH-FREQUENCY VENTILATION; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; PLACENTA; PREGNANCY; PULMONARY SURFACTANTS; RESPIRATORY INSUFFICIENCY; SHEEP;

EID: 84922505453     PISSN: 00223468     EISSN: 15315037     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2014.10.028     Document Type: Article

References (29)

1. Martin JA, Hamilton BE, Ventura SJ, et al. Births: final data for 2010. Natl Vital Stat Rep 2012;61:1-72.
2. Ray KN, Lorch SA. Hospitalization of early preterm, late preterm, and term infants during the first year of life by gestational age. Hosp Pediatr 2013;3:194-203.
3. Boyle EM, Poulsen G, Field DJ, et al. Effects of gestational age at birth on health outcomes at 3 and 5 years of age: population based cohort study. Br Med J 2012;344: e896.
4. Lawn L, McCance RA. Ventures with an artificial placenta. I. Principles and preliminary results. Proc R Soc Lond B Biol Sci 1962;155:500-9.
5. ZapolWM, Kolobow T, Pierce Jevurek GG, et al. Artificial placenta: two days of total extrauterine support of the isolated premature lamb fetus. Science 1969;166:617-8.
6. Callaghan JCME, Hug HE. Studies on lambs of the development of an artificial placenta. Can J Surg 1965;8:208-13.
7. Liggins GC, Howie RN. A controlled trial of antepartum glucocorticoid treatment for prevention of the respiratory distress syndrome in premature infants. Pediatrics 1972;50:515-25.
8. Butler W, Bohn D, Bryan A, et al. Ventilation by high-frequency oscillation in humans. Anesth Analg 1980;59:577-84.
9. Kuwabara Y, Okai T, Imanishi Y, et al. Development of extrauterine fetal incubation system using extracorporeal membrane oxygenator. Artif Organs 1987;11:224-7.
10. YasufukuM, Hisano K, Sakata M, et al. Arterio-venous extracorporealmembrane oxygenation of fetal goat incubated in artificial amniotic fluid (artificial placenta): influence on lung growth and maturation. J Pediatr Surg 1998;33(3):442-8.
11. Awad JA, Cloutier R, Fournier L, et al. Pumpless respiratory assistance using a membrane oxygenator as an artificial placenta: a preliminary study in newborn and preterm lambs. J Investig Surg 1995;8(1):21-30.
12. Reoma JL, Rojas A, Kim AC, et al. Development of an artificial placenta I: pumpless arterio-venous extracorporeal life support in a neonatal sheep model. J Pediatr Surg 2009;44:53-9.
13. Gray BW, El-Sabbagh A, ZakemSJ, et al. Development of an artificial placenta V: 70 h veno-venous extracorporeal life support after ventilatory failure in premature lambs. J Pediatr Surg 2013;48:145-53.
14. Burri PH. Fetal and postnatal development of the lung. Annu Rev Physiol 1984;46: 617-28.
15. Gray BW, El-Sabbagh A, Rojas-Pena A, et al. Development of an artificial placenta IV: 24 hour venovenous extracorporeal life support in premature lambs. ASAIO J 2012; 58:148-54.
16. El-Sabbagh A, Shaffer A, Gray B, et al. Development of an artificial placenta VI: a focus on cerebral oxygenation in a veno-venous extracorporeal life support premature lamb model. Presented at the 58th Annual Conference of the American Society for Artificial Internal Organs. San Francisco, California, June 23-26, 2012; 2012.
17. Unno N, Kuwabara Y, Okai T, et al. Development of an artificial placenta: survival of isolated goat fetuses for three weeks with umbilical arteriovenous extracorporeal membrane oxygenation. Artif Organs 1993;17:996-1003.
18. Docimo SG, Crone RK, Davies P, et al. Pulmonary development in the fetal lamb: morphometric study of the alveolar phase. Anat Rec 1991;229:495-8.
19. Gothberg S, Parker TA, Abman SH, et al. High-frequency oscillatory ventilation and partial liquid ventilation after acute lung injury in premature lambs with respiratory distress syndrome. Crit Care Med 2000;28:2450-6.
20. Kinsella JP, Parker TA, Galan H, et al. Independent and combined effects of inhaled nitric oxide, liquid perfluorochemical, and high-frequency oscillatory ventilation in premature lambs with respiratory distress syndrome. Am J Respir Crit Care Med 1999;159:1220-7.
21. Balasubramaniam J, Del Bigio MR. Animal models of germinal matrix hemorrhage. J Child Neurol 2006;21:365-71.
22. Mallard C, Welin A-K, Peebles D, et al. White matter injury following systemic endotoxemia or asphyxia in the fetal sheep. Neurochem Res 2003;28:215-23.
23. Back S, Riddle A, Dean J, et al. The instrumented fetal sheep as a model of cerebral white matter injury in the premature infant. Neurotherapeutics 2012;9:359-70.
24. Kadri H, Mawla AA, Kazah J. The incidence, timing, and predisposing factors of germinal matrix and intraventricular hemorrhage (GMH/IVH) in preterm neonates. Childs Nerv Syst 2006;22:1086-90.
25. Kaiser JR, Gauss CH, Pont MM, et al. Hypercapnia during the first 3 days of life is associated with severe intraventricular hemorrhage in very low birth weight infants. J Perinatol 2006;26:279-85.
26. Major TC, Brant DO, Burney CP, et al. The hemocompatibility of a nitric oxide generating polymer that catalyzes S-nitrosothiol decomposition in an extracorporeal circulation model. Biomaterials 2011;32:5957-69.
27. Major TC, Brant DO, Reynolds MM, et al. The attenuation of platelet and monocyte activation in a rabbit model of extracorporeal circulation by a nitric oxide releasing polymer. Biomaterials 2010;31:2736-45.
28. Stone D, Frattarelli D, Karthikeyan S, et al. Altered prostaglandin E1 dosage during extracorporeal membrane oxygenation in a newborn with ductal-dependent congenital heart disease. Pediatr Cardiol 2006;27:360-3.
29. Momma K, Nishihara S, Ota Y. Constriction of the fetal ductus arteriosus by glucocorticoid hormones. Pediatr Res 1981;15:19-21.