The hemocompatibility of a nitric oxide generating polymer that catalyzes S-nitrosothiol decomposition in an extracorporeal circulation model

Biomaterials

Volumn 32, Issue 26, 2011, Pages 5957-5969

  Major, Terry C ^a   Brant, David O ^a   Burney, Charles P ^a   Amoako, Kagya A ^a   Annich, Gail M ^a   Meyerhoff, Mark E ^b   Handa, Hitesh ^a,c   Bartlett, Robert H ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c Accord Biomaterials Inc   (United States)

Author keywords

Copper nanoparticles; Hemocompatible polymer coating; Monocyte CD11b; Nitric oxide; Platelet P selectin; S Nitroso acetylpenicillamine (SNAP)

Indexed keywords

CATALYTIC DECOMPOSITION; COPPER NANOPARTICLES; EX-VIVO; EXTRACORPOREAL CIRCULATION; HEMOCOMPATIBILITY; HEMOCOMPATIBLE POLYMER COATING; INNER WALLS; MEAN FLUORESCENCE INTENSITIES; MONOCYTE CD11B; NO CONCENTRATION; P-SELECTIN; PLASMA FIBRINOGEN LEVELS; PLATELET AGGREGATION; POLYMER COATING; POLYMERIC COATINGS; S-NITROSO ACETYLPENICILLAMINE (SNAP); S-NITROSOTHIOLS; THROMBOGENICITY; THROMBORESISTANCE; THROMBUS FORMATION; WESTERN BLOTTING;

COPPER; DIMERS; FLOW CYTOMETRY; NANOPARTICLES; NITRIC OXIDE; NITROGEN REMOVAL; PLATELETS; POLYMER FILMS; POLYMERS;

PLASTIC COATINGS;

COPPER NANOPARTICLE; FIBRINOGEN; HEPARIN; N ACETYL S NITROSOPENICILLAMINE; NANOPARTICLE; NITRIC OXIDE; PADGEM PROTEIN; POLYMER; POLYURETHAN; S NITROSOTHIOL; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DECOMPOSITION; EX VIVO STUDY; EXTRACORPOREAL CIRCULATION; FIBRINOGEN BLOOD LEVEL; FLOW CYTOMETRY; FLUORESCENCE; MATERIAL COATING; NONHUMAN; PRIORITY JOURNAL; RABBIT; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION; THROMBOGENESIS; THROMBOGENICITY; THROMBOSIS; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; EXTRACORPOREAL CIRCULATION; FIBRINOGEN; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; NITRIC OXIDE; POLYMERS; RABBITS; S-NITROSOTHIOLS;

ORYCTOLAGUS CUNICULUS;

EID: 79959915891     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.03.036     Document Type: Article

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