OCT imaging of macrophages: A bright spot in the study of inflammation in human atherosclerosis

JACC: Cardiovascular Imaging

Volumn 8, Issue 1, 2015, Pages 73-75

  Tearney, Guillermo J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Intravascular imaging; Macrophage; Optical coherence tomography; Vulnerable plaque

Indexed keywords

CHLORDANE; CHOLESTEROL; COLLAGEN; ELASTIN;

ADVENTITIA; ALGORITHM; ARTERY MEDIA; ARTERY WALL; ATHEROSCLEROSIS; BLOOD VESSEL WALL; CADAVER; CORONARY ARTERY; CRYSTAL; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; HISTOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; INTIMA; LIGHT SCATTERING; MACROPHAGE; MORPHOLOGY; NOTE; OPTICAL COHERENCE TOMOGRAPHY; PHAGOCYTOSIS; PRIORITY JOURNAL; RADIATION ATTENUATION; RISK FACTOR; CORONARY BLOOD VESSEL; PATHOLOGY;

CORONARY VESSELS; HUMANS; MACROPHAGES; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84922496101     PISSN: 1936878X     EISSN: 18767591     Source Type: Journal    
DOI: 10.1016/j.jcmg.2014.09.019     Document Type: Editorial

References (11)

1. Tearney GJ, Yabushita H, Houser SL, et al. Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography. Circulation 2003;107:113-9.
2. Nakano M, Vorpahl M, Otsuka F, et al. Ex vivo assessment of vascular response to coronary stents by optical frequency domain imaging. J Am Coll Cardiol Img 2012;5:71-82.
3. Kashiwagi M, Liu L, Chu KK, et al. Feasibility of the assessment of cholesterol crystals in human macrophages using micro optical coherence tomography. PloS One 2014;9:e102669.
4. Liu L, Gardecki JA, Nadkarni SK, et al. Imaging the subcellular structure of human coronary atherosclerosis using micro-optical coherence tomography. Nat Med 2011;17:1010-4.
5. Raffel OC, Tearney GJ, Gauthier DD, Halpern EF, Bouma BE, Jang IK. Relationship between a systemic inflammatory marker, plaque inflammation, and plaque characteristics determined by intravascular optical coherence tomography. Arterioscler Thromb Vasc Biol 2007;27:1820-7.
6. Goto I, Itoh T, Kimura T, et al. Morphological and quantitative analysis of vascular wall and neointimal hyperplasia after coronary stenting: comparison of bare-metal and sirolimus-eluting stents using optical coherence tomography. Circ J 2011;75:1633-40.
7. Raffel OC, Merchant FM, Tearney GJ, et al. In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography. Eur Heart J 2008;29: 1721-8.
8. MacNeill BD, Jang IK, Bouma BE, et al. Focal and multi-focal plaque macrophage distributions in patients with acute and stable presentations of coronary artery disease. J Am Coll Cardiol 2004; 44:972-9.
9. Tearney GJ, Regar E, Akasaka T, et al. Consensus standards for acquisition, measurement, and reporting of intravascular optical coherence tomography studies: a report from the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation. J Am Coll Cardiol 2012;59: 1058-72.
10. Tahara S, Morooka T, Wang Z, et al. Intravascular optical coherence tomography detection of atherosclerosis and inflammation in murine aorta. Arterioscler Thromb Vasc Biol 2012;32:1150-7.
11. Phipps JE, Vela D, Hoyt T, et al. Macrophages and intravascular OCT bright spots: a quantitative study. J Am Coll Cardiol Img 2015;8:63-72.