Should an elderly patient with stage V CKD and dementia be started on dialysis?

Clinical Journal of the American Society of Nephrology

Volumn 9, Issue 5, 2014, Pages 971-977

  Ying, Irene ^a   Levitt, Zoe ^b   Jassal, Sarbjit Vanita ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CREATININE;

AGED; ALZHEIMER DISEASE; ARTICLE; BATH; BEHAVIOR; BENEFICENCE; CAREGIVER; CASE REPORT; CHRONIC KIDNEY DISEASE; COGNITIVE DEFECT; COMMUNITY ACQUIRED PNEUMONIA; DECISION MAKING; DEMENTIA; DIALYSIS; FAMILY COUNSELING; FEMALE; GLOMERULUS FILTRATION RATE; GROOMING; HEALTH CARE PLANNING; HEALTH SERVICE; HUMAN; HUMAN RIGHTS; HYPERPHOSPHATEMIA; HYPERTENSION; IRON DEFICIENCY ANEMIA; KIDNEY FUNCTION; MEDICAL PERSONNEL; MORTALITY; NONMALEFICENCE; PATIENT CARE; PATIENT COUNSELING; PRACTICE GUIDELINE; PREMATURE FATALISM; PREVALENCE; QUALITY OF LIFE; SCREENING TEST; SOCIAL ACCEPTANCE; SURVIVAL; TECHNOLOGY; VASCULAR DISEASE; WALKER; COMPLICATION; ETHICS; KIDNEY FAILURE, CHRONIC; PATIENT CARE PLANNING; PATIENT PARTICIPATION; RENAL REPLACEMENT THERAPY;

AGED; BENEFICENCE; DECISION MAKING; DEMENTIA; FEMALE; HUMANS; KIDNEY FAILURE, CHRONIC; PATIENT CARE PLANNING; PATIENT PARTICIPATION; PRACTICE GUIDELINES AS TOPIC; QUALITY OF LIFE; RENAL DIALYSIS; TECHNOLOGY;

EID: 84922479541     PISSN: 15559041     EISSN: 1555905X     Source Type: Journal    
DOI: 10.2215/CJN.05870513     Document Type: Article

References (49)

1. Kurella M, Chertow GM, Luan J, Yaffe K: Cognitive impairment in chronic kidney disease. J Am Geriatr Soc 52: 1863-1869, 2004.
2. Kurella M, Chertow GM, Fried LF, Cummings SR, Harris T, Simonsick E, Satterfield S, Ayonayon H, Yaffe K: Chronic kidney disease and cognitive impairment in the elderly: The health, aging, and body composition study. J Am Soc Nephrol 16: 2127-2133, 2005.
3. Murray AM, Pederson SL, Tupper DE, Hochhalter AK, Miller WA, Li Q, Zaun D, Collins AJ, Kane R, Foley RN: Acute variation in cognitive function in hemodialysis patients: A cohort study with repeated measures. Am J Kidney Dis 50: 270-278, 2007.
4. Weiner DE, Bartolomei K, Scott T, Price LL, Griffith JL, Rosenberg I, Levey AS, Folstein MF, Sarnak MJ: Albuminuria, cognitive functioning, and white matter hyperintensities in homebound elders. Am J Kidney Dis 53: 438-447, 2009.
5. McQuillan R, Jassal SV: Neuropsychiatric complications of chronic kidney disease. Nat Rev Nephrol 6: 471-479, 2010.
6. Yaffe K, Ackerson L, Kurella Tamura M, Le Blanc P, Kusek JW, Sehgal AR, Cohen D, Anderson C, Appel L, Desalvo K, Ojo A, Seliger S, Robinson N, Makos G, Go AS; Chronic Renal Insufficiency Cohort Investigators: Chronic kidney disease and cognitive function in older adults: Findings from the chronic renal insufficiency cohort cognitive study. J Am Geriatr Soc 58: 338-345, 2010.
7. Kurella Tamura M, Xie D, Yaffe K, Cohen DL, Teal V, Kasner SE, Messé SR, Sehgal AR, Kusek J, DeSalvo KB, Cornish-Zirker D, Cohan J, Seliger SL, Chertow GM, Go AS: Vascular risk factors and cognitiveimpairment in chronic kidney disease: The Chronic Renal InsufficiencyCohort (CRIC)study. Clin J AmSoc Nephrol 6: 248-256, 2011.
8. Yamamoto Y, Ohara T, Nagakane Y, Tanaka E, Morii F, Koizumi T, Akiguchi I: Chronic kidney disease, 24-h blood pressure and small vessel diseases are independently associated with cognitive impairment in lacunar infarct patients. Hypertens Res 34: 1276-1282, 2011.
9. Seliger SL, Weiner DE: Cognitive impairment in dialysis patients: Focus on the blood vessels? Am J Kidney Dis 61: 187-190, 2013.
10. Murray AM, Tupper DE, Knopman DS, Gilbertson DT, Pederson SL, Li S, Smith GE, Hochhalter AK, Collins AJ, Kane RL: Cognitive impairment in hemodialysis patients is common. Neurology 67: 216-223, 2006.
11. Kurella M, Yaffe K, Shlipak MG, Wenger NK, Chertow GM: Chronic kidney disease andcognitive impairment in menopausal women. Am J Kidney Dis 45: 66-76, 2005.
12. Kurella M, Mapes DL, Port FK, Chertow GM: Correlates and outcomes of dementia among dialysis patients: The Dialysis Outcomes and Practice Patterns Study. Nephrol Dial Transplant 21: 2543-2548, 2006.
13. Rakowski DA, Caillard S, Agodoa LY, Abbott KC: Dementia as a predictor of mortality in dialysis patients. Clin J Am Soc Nephrol 1: 1000-1005, 2006.
14. Griva K, Stygall J, Hankins M, Davenport A, Harrison M, Newman SP: Cognitive impairment and 7-year mortality in dialysis patients. Am J Kidney Dis 56: 693-703, 2010.
15. Raphael KL, Wei G, Greene T, Baird BC, Beddhu S: Cognitive function and the risk of death in chronic kidney disease. Am J Nephrol 35: 49-57, 2012.
16. Bowling CB, O’Hare AM: Managing older adults with CKD: Individualized versus disease-based approaches. Am J Kidney Dis 59: 293-302, 2012.
17. Murtagh FE, Addington-Hall J, Higginson IJ: The prevalence of symptoms in end-stage renal disease: A systematic review. Adv Chronic Kidney Dis 14: 82-99, 2007.
18. Bourbonnais FF, Tousignant KF: The pain experience of patients on maintenance hemodialysis. Nephrol Nurs J 39: 13-19, quiz 20, 2012.
19. Renal Physicians Association: Shared Decision-Making in the Appropriate Initiation of and Withdrawal from Dialysis Clinical Practice Guideline, 2nd Ed., Rockville, MD, Renal Physicians Association, 2010.
20. Barger-Lux MJ, Heaney RP: For better and worse: The technological imperative in health care. Soc Sci Med 22: 1313-1320, 1986.
21. Katz MH, Grady D, Redberg RF: Undertreatment improves, but overtreatment does not. JAMA Intern Med 173: 93, 2013.
22. Kaufman SR, Shim JK, Russ AJ: Revisiting the biomedicalization of aging: Clinical trends and ethical challenges. Gerontologist 44: 731-738, 2004.
23. Fuchs VR: The growing demand for medical care. N Engl J Med 279: 190-195, 1968.
24. Meeker MA, Jezewski MA: Family decision making at end of life. Palliat Support Care 3: 131-142, 2005.
25. Kaufman SR, Shim JK, Russ AJ: Old age, life extension, and the character of medical choice. J Gerontol B Psychol Sci Soc Sci 61: S175-S184, 2006.
26. Clarke G, Harrison K, Holland A, Kuhn I, Barclay S: How are treatment decisions madeabout artificial nutrition for individuals at risk of lacking capacity? A systematic literature review. PLoS ONE 8: e61475, 2013.
27. Carson RC, Juszczak M, Davenport A, Burns A: Is maximum conservative management an equivalent treatment option to dialysis for elderly patients with significant comorbid disease? Clin J Am Soc Nephrol 4: 1611-1619, 2009.
28. Hussain JA, Mooney A, Russon L: Comparison of survival analysis and palliative care involvement in patients aged over 70 years choosing conservative management or renal replacement therapy in advanced chronic kidney disease. Palliat Med 27: 829-839, 2013.
29. Say R, Murtagh M, Thomson R: Patients’ preference for involvement in medical decision making: A narrative review. Patient Educ Couns 60: 102-114, 2006.
30. Davison SN: End-of-life care preferences and needs: Perceptions of patientswith chronic kidney disease. Clin J Am Soc Nephrol 5: 195-204, 2010.
31. Schell JO, Da Silva-Gane M, Germain MJ: Recent insights into life expectancy with and without dialysis. Curr Opin Nephrol Hypertens 22: 185-192, 2013.
32. Murtagh FE, Cohen LM, Germain MJ: The “no dialysis” option. Adv Chronic Kidney Dis 18: 443-449, 2011.
33. Germain MJ, Davison SN, Moss AH: When enough is enough: The nephrologist’s responsibility in ordering dialysis treatments. Am J Kidney Dis 58: 135-143, 2011.
34. Moss AH: To dialyze or not: The patient with metastatic cancer and AKI in the intensive care unit. Clin J Am Soc Nephrol 7: 1507-1512, 2012.
35. Moss AH: Revised dialysis clinical practice guideline promotes more informed decision-making. Clin J AmSocNephrol 5:2380-2383, 2010.
36. Beauchamp TL, Childress JF: Justice. In: The Principles of Bio-medical Ethics, 5th Ed., edited by Beauchamp TL, Childress JF, Oxford, United Kingdom, Oxford University Press, 2001, pp 225-239.
37. Engelhardt HT, Wildes KW: The four principles of health care ethics and post-modernity: why a libertarian interpretation is unavoidable. In: Principles of Health Care Ethics, edited by Gillon R, New York, John Wiley & Sons, 1994, pp 135-147.
38. Fox CS, Matsushita K, Woodward M, Bilo HJ, Chalmers J, Heerspink HJ, Lee BJ, Perkins RM, Rossing P, Sairenchi T, Tonelli M, Vassalotti JA, Yamagishi K, Coresh J, de Jong PE, Wen CP, Nelson RG; Chronic Kidney Disease Prognosis Consortium: Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: A meta-analysis. Lancet 380: 1662-1673, 2012.
39. Unruh ML, Newman AB, Larive B, Dew MA, Miskulin DC, Greene T, Beddhu S, Rocco MV, Kusek JW, Meyer KB; Hemodi-alysis Study Group: The influence of age on changes in health-related quality of life over three years in a cohort undergoing hemodialysis. J Am Geriatr Soc 56: 1608-1617, 2008.
40. Coppola KM, Ditto PH, Danks JH, Smucker WD: Accuracy of primary care and hospital-based physicians’ predictions of elderly outpatients’ treatment preferences with and without advance directives. Arch Intern Med 161: 431-440, 2001.
41. Lynn J, Arkes HR, Stevens M, Cohn F, Koenig B, Fox E, Dawson NV, Phillips RS, Hamel MB, Tsevat J; Study to Understand Prognoses and Preferences and Risks of Treatment: Rethinking fundamental assumptions: SUPPORT’s implications for future reform. J Am Geriatr Soc 48[Suppl]: S214-S221, 2000.
42. Shalowitz DI, Garrett-Mayer E, Wendler D: The accuracy of surrogate decision makers: A systematic review. Arch Intern Med 166: 493-497, 2006.
43. Lyketsos CG, Steinberg M, Tschanz JT, Norton MC, Steffens DC, Breitner JC: Mental and behavioral disturbances in dementia: Findingsfrom the Cache County StudyonMemoryinAging.Am J Psychiatry 157: 708-714, 2000.
44. Lawlor B: Managing behavioural and psychological symptoms in dementia. Br J Psychiatry 181: 463-465, 2002.
45. Behrman S, Dunn M: Physical restraint of medical inpatients: Unravelling the red tape. Clin Ethics 5: 16-21, 2010.
46. Berzlanovich AM, Schöpfer J, Keil W: Deaths due to physical restraint. Dtsch Arztebl Int 109: 27-32, 2012.
47. Miles SH, Irvine P: Deaths caused by physical restraints. Ger-ontologist 32: 762-766, 1992.
48. Daniels N: Justice, health, and healthcare. Am J Bioeth 1: 2-16, 2001.
49. Martyn SR: Substituted judgment, best interests, and the need for best respect. Camb Q Healthc Ethics 3: 195-208, 1994.