메뉴 건너뛰기




Volumn 30, Issue 1, 2015, Pages 28-36

Which set of embryo variables is most predictive for live birth? A prospective study in 6252 single embryo transfers to construct an embryo score for the ranking and selection of embryos

Author keywords

embryo morphology; embryo score; embryo transfer; implantation potential; prediction

Indexed keywords

ARTICLE; BLASTOMA; COHORT ANALYSIS; CONTROLLED STUDY; EMBRYO; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; GROUPS BY AGE; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; LIVE BIRTH; MAJOR CLINICAL STUDY; PREGNANCY; PREGNANCY RATE; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; CYTOLOGY; EMBRYO DEVELOPMENT; IN VITRO FERTILIZATION; MULTIVARIATE ANALYSIS; ODDS RATIO; STATISTICAL MODEL;

EID: 84922467136     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/deu295     Document Type: Article
Times cited : (59)

References (48)
  • 1
    • 81055124854 scopus 로고    scopus 로고
    • Trophectoderm morphology: An important parameter for predicting live birth after single blastocyst transfer
    • AhlstromA, Westin C, Reismer E, WiklandM, HardarsonT. Trophectoderm morphology: an important parameter for predicting live birth after single blastocyst transfer. Hum Reprod 2011;26:3289-3296.
    • (2011) Hum Reprod , vol.26 , pp. 3289-3296
    • Ahlstroma Westin, C.1    Reismer, E.2    Hardarsont, W.3
  • 2
    • 79957533987 scopus 로고    scopus 로고
    • The Istanbul consensus workshop on embryo assessment: Proceedings of an expert meeting
    • Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Embryology
    • Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Embryology. The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting. Hum Reprod 2011;26: 1270-1283.
    • (2011) Hum Reprod , vol.26 , pp. 1270-1283
  • 3
    • 0033051679 scopus 로고    scopus 로고
    • Temporal and spatial aspects of fragmentation in early human embryos: Possible effects on developmental competence and association with the differential elimination of regulatory proteins from polarized domains
    • Antczak M, Van Blerkom J. Temporal and spatial aspects of fragmentation in early human embryos: possible effects on developmental competence and association with the differential elimination of regulatory proteins from polarized domains. Hum Reprod 1999;14:429-447.
    • (1999) Hum Reprod , vol.14 , pp. 429-447
    • Antczak, M.1    Van Blerkom, J.2
  • 5
    • 32944464054 scopus 로고    scopus 로고
    • Randomized comparison of two different blastocyst grading systems
    • Balaban B, Yakin K, Urman B. Randomized comparison of two different blastocyst grading systems. Fertil Steril 2006;85:559-563.
    • (2006) Fertil Steril , vol.85 , pp. 559-563
    • Balaban, B.1    Yakin, K.2    Urman, B.3
  • 6
    • 84874850952 scopus 로고    scopus 로고
    • Antimullerian hormone levels are strongly associated with live-birth rates after assisted reproduction
    • Brodin T, Hadziosmanovic N, Berglund L, Olovsson M, Holte J. Antimullerian hormone levels are strongly associated with live-birth rates after assisted reproduction. J Clin Endocrinol Metab 2013;98:1107-1114.
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. 1107-1114
    • Brodin, T.1    Hadziosmanovic, N.2    Berglund, L.3    Olovsson, M.4    Holte, J.5
  • 10
    • 33847109797 scopus 로고    scopus 로고
    • Use and misuse of the receiver operating characteristic curve in risk prediction
    • Cook NR. Use and misuse of the receiver operating characteristic curve in risk prediction. Circulation 2007;115:928-935.
    • (2007) Circulation , vol.115 , pp. 928-935
    • Cook, N.R.1
  • 11
    • 0022978937 scopus 로고
    • A formula for scoring human embryo growth rates in in vitro fertilization: Its value in predicting pregnancy and in comparison with visual estimates of embryo quality
    • Cummins JM, Breen TM, Harrison KL, Shaw JM, Wilson LM, Hennessey JF. A formula for scoring human embryo growth rates in in vitro fertilization: its value in predicting pregnancy and in comparison with visual estimates of embryo quality. J In Vitro Fert Embryo Transf 1986;3:284-295.
    • (1986) J in Vitro Fert Embryo Transf , vol.3 , pp. 284-295
    • Cummins, J.M.1    Breen, T.M.2    Harrison, K.L.3    Shaw, J.M.4    Wilson, L.M.5    Hennessey, J.F.6
  • 12
    • 84875579685 scopus 로고    scopus 로고
    • Increased risk of preterm birth in singleton pregnancies after blastocyst versus Day 3 embryo transfer: Canadian ART Register (CARTR) analysis
    • IVF Directors Group of Canadian Fertility and Andrology Society
    • Dar S, Librach CL, Gunby J, Bissonnette F, Cowan L, IVF Directors Group of Canadian Fertility and Andrology Society. Increased risk of preterm birth in singleton pregnancies after blastocyst versus Day 3 embryo transfer: Canadian ART Register (CARTR) analysis. Hum Reprod 2013; 28:924-928.
    • (2013) Hum Reprod , vol.28 , pp. 924-928
    • Dar, S.1    Librach, C.L.2    Gunby, J.3    Bissonnette, F.4    Cowan, L.5
  • 14
    • 0034045087 scopus 로고    scopus 로고
    • Blastocyst score affects implantation and pregnancy outcome: Towards a single blastocyst transfer
    • Gardner DK, Lane M, Stevens J, Schlenker T, Schoolcraft WB. Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer. Fertil Steril 2000;73:1155-1158.
    • (2000) Fertil Steril , vol.73 , pp. 1155-1158
    • Gardner, D.K.1    Lane, M.2    Stevens, J.3    Schlenker, T.4    Schoolcraft, W.B.5
  • 16
    • 0028792056 scopus 로고
    • Embryo score to predict implantation after in-vitro fertilization: Based on 957 single embryo transfers
    • Giorgetti C, Terriou P, Auquier P, Hans E, Spach JL, Salzmann J, Roulier R. Embryo score to predict implantation after in-vitro fertilization: based on 957 single embryo transfers. Hum Reprod 1995;10:2427-2431.
    • (1995) Hum Reprod , vol.10 , pp. 2427-2431
    • Giorgetti, C.1    Terriou, P.2    Auquier, P.3    Hans, E.4    Spach, J.L.5    Salzmann, J.6    Roulier, R.7
  • 17
    • 34447297309 scopus 로고    scopus 로고
    • Limited value of morphological assessment at days 1 and 2 to predict blastocyst development potential: A prospective study based on 4042 embryos
    • Guerif F, Le Gouge A, Giraudeau B, Poindron J, Bidault R, Gasnier O, Royere D. Limited value of morphological assessment at days 1 and 2 to predict blastocyst development potential: a prospective study based on 4042 embryos. Hum Reprod 2007;22:1973-1981.
    • (2007) Hum Reprod , vol.22 , pp. 1973-1981
    • Guerif, F.1    Le Gouge, A.2    Giraudeau, B.3    Poindron, J.4    Bidault, R.5    Gasnier, O.6    Royere, D.7
  • 18
    • 0035138041 scopus 로고    scopus 로고
    • Humanembryos with unevenly sized blastomeres have lower pregnancy and implantation rates: Indications for aneuploidy and multinucleation
    • HardarsonT, Hanson C, Sjogren A, Lundin K.Humanembryos with unevenly sized blastomeres have lower pregnancy and implantation rates: indications for aneuploidy and multinucleation. Hum Reprod 2001; 16:313-318.
    • (2001) Hum Reprod , vol.16 , pp. 313-318
    • Hardarsont Hanson, C.1    Sjogren, A.2    Lundin, K.3
  • 19
    • 0030069896 scopus 로고    scopus 로고
    • Multivariable prognostic models: Issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors
    • Harrell FE, Jr., Lee KL, Mark DB. Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med 1996;15:361-387.
    • (1996) Stat Med , vol.15 , pp. 361-387
    • Harrell, F.E.1    Lee, K.L.2    Mark, D.B.3
  • 20
    • 84888436824 scopus 로고    scopus 로고
    • Diminished effect of maternal age on implantation after preimplantation genetic diagnosis with array comparative genomic hybridization
    • PGD Practitioners Group
    • Harton GL, Munne S, Surrey M, Grifo J, Kaplan B, McCulloh DH, Griffin DK, Wells D, PGD Practitioners Group. Diminished effect of maternal age on implantation after preimplantation genetic diagnosis with array comparative genomic hybridization. Fertil Steril 2013;100:1695-1703.
    • (2013) Fertil Steril , vol.100 , pp. 1695-1703
    • Harton, G.L.1    Munne, S.2    Surrey, M.3    Grifo, J.4    Kaplan, B.5    McCulloh, D.H.6    Griffin, D.K.7    Wells, D.8
  • 21
    • 84888430066 scopus 로고    scopus 로고
    • Atime to look back: Analysis of morphokinetic characteristics of human embryo development
    • e1604
    • Herrero J, Tejera A, Albert C, Vidal C, de Los Santos MJ, Meseguer M.Atime to look back: analysis of morphokinetic characteristics of human embryo development. Fertil Steril 2013;100:1602-1609 e1604.
    • (2013) Fertil Steril , vol.100 , pp. 1602-1609
    • Herrero, J.1    Tejera, A.2    Albert, C.3    Vidal, C.4    De Los Santos, M.J.5    Meseguer, M.6
  • 22
    • 33846545722 scopus 로고    scopus 로고
    • Construction of an evidence-based integrated morphology cleavage embryo score for implantation potential of embryos scored and transferred on day 2 after oocyte retrieval
    • Holte J, Berglund L, Milton K, Garello C, Gennarelli G, Revelli A, Bergh T. Construction of an evidence-based integrated morphology cleavage embryo score for implantation potential of embryos scored and transferred on day 2 after oocyte retrieval. Hum Reprod 2007;22:548-557.
    • (2007) Hum Reprod , vol.22 , pp. 548-557
    • Holte, J.1    Berglund, L.2    Milton, K.3    Garello, C.4    Gennarelli, G.5    Revelli, A.6    Bergh, T.7
  • 24
    • 80052190146 scopus 로고    scopus 로고
    • Antral follicle counts are strongly associated with live-birth rates after assisted reproduction with superior treatment outcome in women with polycystic ovaries
    • Holte J, Brodin T, Berglund L, Hadziosmanovic N, Olovsson M, Bergh T. Antral follicle counts are strongly associated with live-birth rates after assisted reproduction, with superior treatment outcome in women with polycystic ovaries. Fertil Steril 2011b;96:594-599.
    • (2011) Fertil Steril , vol.96 , pp. 594-599
    • Holte, J.1    Brodin, T.2    Berglund, L.3    Hadziosmanovic, N.4    Olovsson, M.5    Bergh, T.6
  • 26
    • 84887061667 scopus 로고    scopus 로고
    • Using the ovarian sensitivity index to define poor, normal, and high response after controlled ovarian hyperstimulation in the long gonadotropin-releasing hormone-agonist protocol: Suggestions for a new principle to solve an old problem
    • Huber M, Hadziosmanovic N, Berglund L, Holte J. Using the ovarian sensitivity index to define poor, normal, and high response after controlled ovarian hyperstimulation in the long gonadotropin-releasing hormone-agonist protocol: suggestions for a new principle to solve an old problem. Fertil Steril 2013;100:1270-1276.
    • (2013) Fertil Steril , vol.100 , pp. 1270-1276
    • Huber, M.1    Hadziosmanovic, N.2    Berglund, L.3    Holte, J.4
  • 27
    • 77957191234 scopus 로고    scopus 로고
    • Blastocyst versus cleavage stage transfer in in vitro fertilization: Differences in neonatal outcome?
    • Kallen B, Finnstrom O, Lindam A, Nilsson E, Nygren KG, Olausson PO. Blastocyst versus cleavage stage transfer in in vitro fertilization: differences in neonatal outcome? Fertil Steril 2010;94:1680-1683.
    • (2010) Fertil Steril , vol.94 , pp. 1680-1683
    • Kallen, B.1    Finnstrom, O.2    Lindam, A.3    Nilsson, E.4    Nygren, K.G.5    Olausson, P.O.6
  • 30
    • 84875294415 scopus 로고    scopus 로고
    • Morphological systems of human embryo assessment and clinical evidence
    • Machtinger R, Racowsky C. Morphological systems of human embryo assessment and clinical evidence. Reprod Biomed Online 2013;26:210-221.
    • (2013) Reprod Biomed Online , vol.26 , pp. 210-221
    • Machtinger, R.1    Racowsky, C.2
  • 33
    • 11144288616 scopus 로고    scopus 로고
    • Penalized maximum likelihood estimation to directly adjust diagnostic and prognostic prediction models for overoptimism: A clinical example
    • Moons KG, Donders AR, Steyerberg EW, Harrell FE. Penalized maximum likelihood estimation to directly adjust diagnostic and prognostic prediction models for overoptimism: a clinical example. J Clin Epidemiol 2004;57:1262-1270.
    • (2004) J Clin Epidemiol , vol.57 , pp. 1262-1270
    • Moons, K.G.1    Donders, A.R.2    Steyerberg, E.W.3    Harrell, F.E.4
  • 34
    • 68949200299 scopus 로고    scopus 로고
    • Is there an advantage in scoring early embryos on more than one day?
    • Racowsky C, Ohno-Machado L, Kim J, Biggers JD. Is there an advantage in scoring early embryos on more than one day? Hum Reprod 2009; 24:2104-2113.
    • (2009) Hum Reprod , vol.24 , pp. 2104-2113
    • Racowsky, C.1    Ohno-Machado, L.2    Kim, J.3    Biggers, J.D.4
  • 35
    • 34247481887 scopus 로고    scopus 로고
    • Late stages of embryo progression are a much better predictor of clinical pregnancy than early cleavage in intracytoplasmic sperm injection and in vitro fertilization cycles with blastocyst-stage transfer
    • Rehman KS, Bukulmez O, Langley M, Carr BR, Nackley AC, Doody KM, Doody KJ. Late stages of embryo progression are a much better predictor of clinical pregnancy than early cleavage in intracytoplasmic sperm injection and in vitro fertilization cycles with blastocyst-stage transfer. Fertil Steril 2007;87:1041-1052.
    • (2007) Fertil Steril , vol.87 , pp. 1041-1052
    • Rehman, K.S.1    Bukulmez, O.2    Langley, M.3    Carr, B.R.4    Nackley, A.C.5    Doody, K.M.6    Doody, K.J.7
  • 37
    • 0037674976 scopus 로고    scopus 로고
    • The biological basis of non-invasive strategies for selection of human oocytes and embryos
    • Scott L. The biological basis of non-invasive strategies for selection of human oocytes and embryos. Hum Reprod Update 2003;9:237-249.
    • (2003) Hum Reprod Update , vol.9 , pp. 237-249
    • Scott, L.1
  • 38
    • 33749257662 scopus 로고    scopus 로고
    • Prediction of embryo developmental potential and pregnancy based on early stage morphological characteristics
    • Sjoblom P, Menezes J, Cummins L, Mathiyalagan B, CostelloMF. Prediction of embryo developmental potential and pregnancy based on early stage morphological characteristics. Fertil Steril 2006;86:848-861.
    • (2006) Fertil Steril , vol.86 , pp. 848-861
    • Sjoblom, P.1    Menezes, J.2    Cummins, L.3    Mathiyalagan, B.4    Costello, M.F.5
  • 39
  • 40
    • 0023222560 scopus 로고
    • Ultrastructural and autoradiographic observations on multinucleated blastomeres of human cleaving embryos obtained by in-vitro fertilization
    • Tesarik J, Kopecny V, Plachot M, Mandelbaum J. Ultrastructural and autoradiographic observations on multinucleated blastomeres of human cleaving embryos obtained by in-vitro fertilization. Hum Reprod 1987; 2:127-136.
    • (1987) Hum Reprod , vol.2 , pp. 127-136
    • Tesarik, J.1    Kopecny, V.2    Plachot, M.3    Mandelbaum, J.4
  • 44
    • 0035130981 scopus 로고    scopus 로고
    • Calculating the implantation potential of day 3 embryos in women younger than 38 years of age: A new model
    • Van Royen E, Mangelschots K, De Neubourg D, Laureys I, Ryckaert G, Gerris J. Calculating the implantation potential of day 3 embryos in women younger than 38 years of age: a new model. Hum Reprod 2001; 16:326-332.
    • (2001) Hum Reprod , vol.16 , pp. 326-332
    • Van Royen, E.1    Mangelschots, K.2    De Neubourg, D.3    Laureys, I.4    Ryckaert, G.5    Gerris, J.6
  • 46
    • 79959719101 scopus 로고    scopus 로고
    • Utility of the national embryo morphology data collection by the Society for Assisted Reproductive Technologies (SART): Correlation between day-3 morphology grade and live-birth outcome
    • Vernon M, Stern JE, Ball GD, Wininger D, Mayer J, Racowsky C. Utility of the national embryo morphology data collection by the Society for Assisted Reproductive Technologies (SART): correlation between day-3 morphology grade and live-birth outcome. Fertil Steril 2011;95:2761-2763.
    • (2011) Fertil Steril , vol.95 , pp. 2761-2763
    • Vernon, M.1    Stern, J.E.2    Ball, G.D.3    Wininger, D.4    Mayer, J.5    Racowsky, C.6
  • 47
    • 0024205301 scopus 로고
    • Models for longitudinal data: A generalized estimating equation approach
    • Zeger SL, Liang KY, Albert PS. Models for longitudinal data: a generalized estimating equation approach. Biometrics 1988;44:1049-1060.
    • (1988) Biometrics , vol.44 , pp. 1049-1060
    • Zeger, S.L.1    Liang, K.Y.2    Albert, P.S.3
  • 48
    • 0030875364 scopus 로고    scopus 로고
    • Embryo morphology or cleavage stage: How to select the best embryos for transfer after in-vitro fertilization
    • Ziebe S, Petersen K, Lindenberg S, Andersen AG, Gabrielsen A, Andersen AN. Embryo morphology or cleavage stage: how to select the best embryos for transfer after in-vitro fertilization. Hum Reprod 1997; 12:1545-1549.
    • (1997) Hum Reprod , vol.12 , pp. 1545-1549
    • Ziebe, S.1    Petersen, K.2    Lindenberg, S.3    Andersen, A.G.4    Gabrielsen, A.5    Andersen, A.N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.